China Kadoorie Biobank
The China Kadoorie Biobank is acquiring genomic data on half a million Chinese participants. In 2022 Genome-wide genotyping had been conducted for more than 100,000 participants using custom-designed Axiom® arrays.It collected questionnaire and physical data and blood samples on 510,000 men and women aged between 30 and 79 from 10 regions in China between 2004-2008 with the aim of investigating chronic diseases (e.g. heart attack, stroke, diabetes, and cancer). Participants have been linked to mortality registers and nationwide health systems and a sub-group of 25,000 are retested every few years. It is a joint venture by the University of Oxford’s Clinical Trial Service Unit & Epidemiological Studies Unit and the Chinese Academy of Medical Sciences.
Research based on the biobank published by the American Thoracic Society in 2018 found that respiratory disease hospitalization or death were 36% higher among people who used wood or coal for cooking compared to those who used electricity or gas.
A study published in Heart based on the biobank found that people who ate an egg a day had a lower incidence of cardiovascular disease overall than those who ate no eggs. They had a 25% lower incidence of hemorrhagic stroke, and a 12% reduction in risk of ischemic heart disease.
A study published in 2022 examined the relative risk of mortality associated with five individual and combined lifestyle factors - never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, and healthy body shape - and established that they could be associated with substantial gains in life expectancy in the Chinese population. Provided by Wikipedia
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61
Seasonal variation in blood pressure and its relationship with outdoor temperature in 10 diverse regions of China: the China Kadoorie Biobank. by Lewington, S, Li, L, Sherliker, P, Guo, Y, Millwood, I, Bian, Z, Whitlock, G, Yang, L, Collins, R, Chen, J, Wu, X, Wang, S, Hu, Y, Jiang, L, Yang, L, Lacey, B, Peto, R, Chen, Z, China Kadoorie Biobank study collaboration
Published 2012Journal article -
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Association between fresh fruit consumption and the risk of chronic obstructive pulmonary disease-related hospitalization and death in Chinese adults: A prospective cohort study by Xin Huang, Jiachen Li, Weihua Cao, Jun Lyu, Yu Guo, Pei Pei, Qingmei Xia, Huaidong Du, Yiping Chen, Yang Ling, Rene Kerosi, Rebecca Stevens, Xujun Yang, Junshi Chen, Canqing Yu, Zhengming Chen, Liming Li, on behalf of China Kadoorie Biobank, Peifang Wei
Published 2023-10-01
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A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits by Yunqing Zhu, Zhenhuang Zhuang, Jun Lv, Dianjianyi Sun, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Yiping Chen, Huaidong Du, Fang Liu, Rebecca Stevens, Junshi Chen, Zhengming Chen, Liming Li, Canqing Yu, On behalf of the China Kadoorie Biobank Collaborative Group
Published 2024-03-01
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Genetic influences on alcohol flushing in East Asian populations by Yoonsu Cho, Kuang Lin, Su-Hyun Lee, Canqing Yu, Dan Schmidt Valle, Daniel Avery, Jun Lv, Keumji Jung, Liming Li, George Davey Smith, China Kadoorie Biobank Collaborative Group, Dianjianyi Sun, Zhengming Chen, Iona Y. Millwood, Gibran Hemani, Robin G. Walters
Published 2023-10-01
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Association of egg consumption, metabolic markers, and risk of cardiovascular diseases: A nested case-control study by Lang Pan, Lu Chen, Jun Lv, Yuanjie Pang, Yu Guo, Pei Pei, Huaidong Du, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Weiwei Gong, Junshi Chen, Canqing Yu, Zhengming Chen, Liming Li, on behalf of China Kadoorie Biobank Collaborative Group
Published 2022-05-01
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Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries. by Andrew B Linden, Robert Clarke, Imen Hammami, Jemma C Hopewell, Yu Guo, William N Whiteley, Kuang Lin, Iain Turnbull, Yiping Chen, Canqing Yu, Jun Lv, Alison Offer, Derrick Bennett, Robin G Walters, Liming Li, Zhengming Chen, Sarah Parish, China Kadoorie Biobank Collaborative Group
Published 2022-04-01
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Device-measured movement behaviours in over 20,000 China Kadoorie Biobank participants by Yuanyuan Chen, Shing Chan, Derrick Bennett, Xiaofang Chen, Xianping Wu, Yalei Ke, Jun Lv, Dianjianyi Sun, Lang Pan, Pei Pei, Ling Yang, Yiping Chen, Junshi Chen, Zhengming Chen, Liming Li, Huaidong Du, Canqing Yu, Aiden Doherty, on behalf of the China Kadoorie Biobank Collaborative Group
Published 2023-11-01
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Multimorbidity patterns and association with mortality in 0.5 million Chinese adults by Junning Fan, Zhijia Sun, Canqing Yu, Yu Guo, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Dianjianyi Sun, Yuanjie Pang, Jun Zhang, Simon Gilbert, Daniel Avery, Junshi Chen, Zhengming Chen, Jun Lyu, Liming Li, Jing Ni, On Behalf of the China Kadoorie Biobank Collaborative Group
Published 2022-03-01
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Genetic predisposition to type 2 diabetes and risk of subclinical atherosclerosis and cardiovascular diseases among 160,000 Chinese adults by Gan, W, Bragg, F, Walters, R, Millwood, I, Lin, K, Chen, Y, Guo, Y, Vaucher, J, Bian, Z, Bennett, D, Lv, J, Yu, C, Mahajan, A, Clarke, R, Li, L, Holmes, M, McCarthy, M, Chen, Z, China Kadoorie Biobank Collaborative Group
Published 2019Journal article -
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Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease by Jiahui Si, Lu Chen, Canqing Yu, Yu Guo, Dianjianyi Sun, Yuanjie Pang, Iona Y. Millwood, Robin G. Walters, Ling Yang, Yiping Chen, Huaidong Du, Shixian Feng, Xiaoming Yang, Daniel Avery, Junshi Chen, Zhengming Chen, Liming Liang, Liming Li, Jun Lv, the China Kadoorie Biobank Collaborative Group
Published 2023-03-01
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71
Mendelian randomisation study of body composition and depression in people of East Asian ancestry highlights potential setting-specific causality by Jessica O’Loughlin, Francesco Casanova, Zammy Fairhurst-Hunter, Amanda Hughes, Jack Bowden, Edward R. Watkins, Rachel M. Freathy, Iona Y. Millwood, Kuang Lin, Zhengming Chen, Liming Li, Jun Lv, China Kadoorie Biobank Collaborative Group, Robin G. Walters, Laura D. Howe, Karoline Kuchenbaecker, Jessica Tyrrell
Published 2023-02-01
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Fresh fruit consumption in relation to incident diabetes and diabetic vascular complications: A 7-y prospective study of 0.5 million Chinese adults by Du, H, Li, L, Bennett, D, Guo, Y, Turnbull, I, Yang, L, Bragg, F, Bian, Z, Chen, Y, Chen, J, Millwood, I, Sansome, S, Ma, L, Huang, Y, Zhang, N, Zheng, X, Sun, Q, Key, T, Collins, R, Peto, R, Chen, Z, China Kadoorie Biobank study
Published 2017Journal article -
73
Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank by Du, H, Guo, Y, Bennett, DA, Bragg, F, Bian, Z, Chadni, M, Yu, C, Chen, Y, Tan, Y, Millwood, IY, Gan, W, Yang, L, Yao, P, Luo, G, Li, J, Qin, Y, Lv, J, Lin, X, Key, T, Chen, J, Clarke, R, Li, L, Chen, Z, China Kadoorie Biobank collaborative group
Published 2020Journal article -
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Association of CETP gene variants with risk for vascular and nonvascular diseases among Chinese adults by Millwood, I, Bennett, D, Holmes, M, Boxall, R, Guo, Y, Bian, Z, Yang, L, Sansome, S, Chen, Y, Du, H, Yu, C, Hacker, A, Reilly, D, Tan, Y, Hill, M, Chen, J, Peto, R, Shen, H, Collins, R, Clarke, R, Li, L, Walters, R, Chen, Z, on behalf of the China Kadoorie Biobank Collaborative Group
Published 2017Journal article -
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Associations Between Hepatitis B Virus Infection and Risk of All Cancer Types by Song, C, Lv, J, Liu, Y, Chen, J, Ge, Z, Zhu, J, Dai, J, Du, L, Yu, C, Guo, Y, Bian, Z, Yang, L, Chen, Y, Chen, Z, Liu, J, Jiang, J, Zhu, L, Zhai, X, Jiang, Y, Ma, H, Jin, G, Shen, H, Li, L, Hu, Z, China Kadoorie Biobank Collaborative Group
Published 2019Journal article -
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Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores: evidence from the China Kadoorie Biobank by Songchun Yang, Dong Sun, Zhijia Sun, Canqing Yu, Yu Guo, Jiahui Si, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Yiping Chen, Huaidong Du, Zengchang Pang, Dan Schmidt, Rebecca Stevens, Robert Clarke, Junshi Chen, Zhengming Chen, Jun Lv, Liming Li, On Behalf of the China Kadoorie Biobank Collaborative Group, Jing Ni
Published 2023-10-01
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Cooking fuels and risk of all-cause and cardiopulmonary mortality in urban China: A prospective cohort study by Yu, K, Lv, J, Qiu, G, Yang, L, Yu, C, Guo, Y, Bian, Z, Chen, Y, Wang, C, Hu, FB, Pan, A, Chen, Z, Liang, L, Li, L, Wu, T
Published 2020Other Authors: “…China Kadoorie Biobank Study…”
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Associations of alcohol intake with subclinical carotid atherosclerosis in 22,000 Chinese adults by Zhou, T, Im, PK, Hariri, P, Du, H, Guo, Y, Lin, K, Yang, L, Yu, C, Chen, Y, Sohoni, R, Avery, D, Guan, M, Yang, M, Lv, J, Clarke, R, Li, L, Walters, RG, Chen, Z, Millwood, IY
Published 2023Other Authors: “… China Kadoorie Biobank Group…”
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Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults by Chun, M, Clarke, R, Zhu, T, Clifton, D, Bennett, D, Chen, Y, Yang, L, Chen, Z, Cairns, B
Published 2021Other Authors: “…China Kadoorie Biobank Collaborative Group…”
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Development, validation and comparison of multivariable risk scores for prediction of total stroke and stroke types in Chinese adults: a prospective study of 0.5 million adults by Chun, M, Clarke, R, Zhu, T, Clifton, D, Bennett, DA, Chen, Y, Guo, Y, Pei, P, Lv, J, Yu, C, Yang, L, Li, L, Chen, Z, Cairns, BJ
Published 2022Other Authors: “…China Kadoorie Biobank Collaborative Group…”
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