NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease by Schwerd, T, Bryant, RV, Pandey, S, Capitani, M, Meran, L, Cazier, JB, Jung, J, Mondal, K, Parkes, M, Mathew, CG, Fiedler, K, McCarthy, DJ, Sullivan, PB, Rodrigues, A, Travis, SPL, Moore, C, Sambrook, J, Ouwehand, WH, Roberts, DJ, Danesh, J, Russell, RK, Wilson, DC, Kelsen, JR, Cornall, R, Denson, LA, Kugathasan, S, Knaus, UG, Serra, EG, Anderson, CA, Duerr, RH, McGovern, DP, Cho, J, Powrie, F, Li, VS, Muise, AM, Uhlig, HH

The Radio to GeV Afterglow of GRB 221009A by Tanmoy Laskar, Kate D. Alexander, Raffaella Margutti, Tarraneh Eftekhari, Ryan Chornock, Edo Berger, Yvette Cendes, Anne Duerr, Daniel A. Perley, Maria Edvige Ravasio, Ryo Yamazaki, Eliot H. Ayache, Thomas Barclay, Rodolfo Barniol Duran, Shivani Bhandari, Daniel Brethauer, Collin T. Christy, Deanne L. Coppejans, Paul Duffell, Wen-fai Fong, Andreja Gomboc, Cristiano Guidorzi, Jamie A. Kennea, Shiho Kobayashi, Andrew Levan, Andrei P. Lobanov, Brian D. Metzger, Eduardo Ros, Genevieve Schroeder, P. K. G. Williams

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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models by Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L. McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrian Plaza, Aranzazu Sierra-Ramirez, Manuel Perez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J. Hofer, Christoph Magnes, Frank Madeo, Janet S. Duerr, Oscar J. Pozo, Maximo-Ibo Galindo, Isabel del Pino, Riekelt H. Houtkooper, Diego Megias, Jose Viña, Mari Carmen Gomez-Cabrera, Pablo J. Fernandez-Marcos

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Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans by Kelly E. Seaton, Aaron Deal, Xue Han, Shuying S. Li, Ashley Clayton, Jack Heptinstall, Ann Duerr, Mary A. Allen, Xiaoying Shen, Sheetal Sawant, Nicole L. Yates, Paul Spearman, Gavin Churchyard, Paul A. Goepfert, Janine Maenza, Glenda Gray, Giuseppe Pantaleo, Laura Polakowski, Harriet L. Robinson, Shannon Grant, April K. Randhawa, Ying Huang, Cecilia Morgan, Nicole Grunenberg, Shelly Karuna, Peter B. Gilbert, M. Juliana McElrath, Yunda Huang, Georgia D. Tomaras, NIAID HIV Vaccine Trials Network (HVTN) 076, 088, 086, 096, 097, 205 Study Teams

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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients by Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman Van Vleck, Girish Nadkarni, Lee A. Denson, Harry Ostrer, Adam P. Levine, Elena R. Schiff, Anthony W. Segal, Subra Kugathasan, Peter D. Stenson, David N. Cooper, L. Philip Schumm, Scott Snapper, Mark J. Daly, Talin Haritunians, Richard H. Duerr, Mark S. Silverberg, John D. Rioux, Steven R. Brant, Dermot P. B. McGovern, Judy H. Cho, Yuval Itan

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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study by Cleynen, I, Boucher, G, Jostins, L, Schumm, LP, Zeissig, S, Ahmad, T, Andersen, V, Andrews, JM, Annese, V, Brand, S, Brant, SR, Cho, JH, Daly, MJ, Dubinsky, M, Duerr, RH, Ferguson, LR, Franke, A, Gearry, RB, Goyette, P, Hakonarson, H, Halfvarson, J, Hov, JR, Huang, H, Kennedy, NA, Kupcinskas, L, Lawrance, IC, Lee, JC, Satsangi, J, Schreiber, S, Théâtre, E, Van Der Meulen-De Jong, AE, Weersma, RK, Wilson, DC, International Inflammatory Bowel Disease Genetics Consortium, Parkes, M, Vermeire, S, Rioux, JD, Mansfield, J, Silverberg, MS, Radford-Smith, G, McGovern, DPB, Barrett, JC, Lees, CW

Fine-mapping inflammatory bowel disease loci to single-variant resolution by Huang, H, Fang, M, Jostins, L, Umićević Mirkov, M, Boucher, G, Anderson, C, Andersen, V, Cleynen, I, Cortes, A, Crins, F, D'Amato, M, Deffontaine, V, Dmitrieva, J, Docampo, E, Elansary, M, Farh, K, Franke, A, Gori, A, Goyette, P, Halfvarson, J, Haritunians, T, Knight, J, Lawrance, I, Lees, C, Louis, E, Mariman, R, Meuwissen, T, Mni, M, Momozawa, Y, Parkes, M, Spain, S, Théâtre, E, Trynka, G, Satsangi, J, Van Sommeren, S, Vermeire, S, Xavier, R, International Inflammatory Bowel Disease Genetics Consortium, Weersma, R, Duerr, R, Mathew, C, Rioux, J, McGovern, D, Cho, J, Georges, M, Daly, M, Barrett, J

Immune Correlates of Disease Progression in Linked HIV-1 Infection by Michael Tuen, Jude S. Bimela, Jude S. Bimela, Andrew N. Banin, Andrew N. Banin, Shilei Ding, Shilei Ding, Gordon W. Harkins, Svenja Weiss, Vincenza Itri, Allison R. Durham, Stephen F. Porcella, Sonal Soni, Luzia Mayr, Josephine Meli, Josephine Meli, Judith N. Torimiro, Judith N. Torimiro, Marcel Tongo, Marcel Tongo, Xiaohong Wang, Xiang-Peng Kong, Arthur Nádas, Daniel E. Kaufmann, Daniel E. Kaufmann, Daniel E. Kaufmann, Zabrina L. Brumme, Zabrina L. Brumme, Aubin J. Nanfack, Aubin J. Nanfack, Aubin J. Nanfack, Thomas C. Quinn, Thomas C. Quinn, Susan Zolla-Pazner, Andrew D. Redd, Andrew D. Redd, Andrés Finzi, Andrés Finzi, Andrés Finzi, Miroslaw K. Gorny, Phillipe N. Nyambi, Phillipe N. Nyambi, Ralf Duerr

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Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohortsResearch in context by Stephanie J.W. Shoop-Worrall, Saskia Lawson-Tovey, Lucy R. Wedderburn, Kimme L. Hyrich, Nophar Geifman, Aline Kimonyo, Alyssia McNeece, Andrew Dick, Andrew Morris, Annie Yarwood, Athimalaipet Ramanan, Bethany R. Jebson, Chris Wallace, Daniela Dastros-Pitei, Damian Tarasek, Elizabeth Ralph, Emil Carlsson, Emily Robinson, Emma Sumner, Fatema Merali, Fatjon Dekaj, Helen Neale, Hussein Al-Mossawi, Jacqui Roberts, Jenna F. Gritzfeld, Joanna Fairlie, John Bowes, John Ioannou, Kimme L. Hyrich, Lucy R. Wedderburn, Melissa Kartawinata, Melissa Tordoff, Michael Barnes, Michael W. Beresford, Michael Stadler, Nophar Geifman, Paul Martin, Rami Kallala, Sandra Ng, Samantha Smith, Sarah Clarke, Saskia Lawson-Tovey, Soumya Raychaudhuri, Stephanie J.W. Shoop-Worrall, Stephen Eyre, Sumanta Mukherjee, Teresa Duerr, Thierry Sornasse, Vasiliki Alexiou, Victoria J. Burton, Wei-Yu Lin, Wendy Thomson, Zoe Wanstall

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A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis by Rivas, MA, Graham, D, Sulem, P, Stevens, C, Desch, AN, Goyette, P, Gudbjartsson, D, Jonsdottir, I, Thorsteinsdottir, U, Degenhardt, F, Mucha, S, Kurki, MI, Li, D, D'Amato, M, Annese, V, Vermeire, S, Weersma, RK, Halfvarson, J, Paavola-Sakki, P, Lappalainen, M, Lek, M, Cummings, B, Tukiainen, T, Haritunians, T, Halme, L, Koskinen, LL, Ananthakrishnan, AN, Luo, Y, Heap, GA, Visschedijk, MC, MacArthur, DG, Neale, BM, Ahmad, T, Anderson, CA, Brant, SR, Duerr, RH, Silverberg, MS, Cho, JH, Palotie, A, Saavalainen, P, Kontula, K, Färkkilä, M, McGovern, DP, Franke, A, Stefansson, K, Rioux, JD, Xavier, RJ, Daly, MJ, Barrett, J, de Lane, K, Edwards, C, Hart, A, Hawkey, C, Jostins, L, Kennedy, N, Lamb, C, Lee, J, Lees, C, Mansfield, J, Mathew, C, Mowatt, C, Newman, B, Nimmo, E, Parkes, M, Pollard, M, Prescott, N, Randall, J, Rice, D, Satsangi, J, Simmons, A, Tremelling, M, Uhlig, H, Wilson, D, Abraham, C, Achkar, JP, Bitton, A, Boucher, G, Croitoru, K, Fleshner, P, Glas, J, Kugathasan, S, Limbergen, JV, Milgrom, R, Proctor, D, Regueiro, M, Schumm, PL, Sharma, Y, Stempak, JM, Targan, SR, Wang, MH

A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease by Plagnol, V, Nalls, M, Bras, J, Hernandez, D, Sharma, M, Sheerin, U, Saad, M, Simon-Sanchez, J, Schulte, C, Lesage, S, Sveinbjornsdottir, S, Amouyel, P, Arepalli, S, Band, G, Barker, R, Bellinguez, C, Ben-Shlomo, Y, Berendse, H, Berg, D, Bhatia, K, de Bie, R, Biffi, A, Bloem, B, Bochdanovits, Z, Bonin, M, Brockmann, K, Brooks, J, Burn, D, Charlesworth, G, Chen, H, Chinnery, P, Chong, S, Clarke, C, Cookson, MR, Cooper, J, Corvol, J, Counsell, C, Damier, P, Dartigues, J, Deloukas, P, Deuschl, G, Dexter, D, van Dijk, K, Dillman, A, Durif, F, Duerr, A, Edkins, S, Evans, JR, Foltynie, T, Freeman, C, Gao, J, Gardner, M, Gibbs, JR, Goate, A, Gray, E, Guerreiro, R, Gustafsson, O, Harris, C, Hellenthal, G, van Hilten, J, Hofman, A, Hollenbeck, A, Holton, J, Hu, M, Huang, X, Huber, H, Hudson, G, Hunt, SE, Huttenlocher, J, Illig, T, Jonsson, P, Langford, C, Lees, A, Lichtner, P, Limousin, P, Lopez, G, Lorenz, D, McNeill, A, Moorby, C, Moore, M, Morris, H, Morrison, K, Mudanohwo, E, O'Sullivan, S, Pearson, J, Pearson, R, Perlmutter, J, Petursson, H, Pirinen, M, Pollak, P, Post, B, Potter, S, Ravina, B, Revesz, T, Riess, O, Rivadeneira, F, Rizzu, P, Ryten, M, Sawcer, S, Schapira, A, Scheffer, H, Shaw, K, Shoulson, I, Sidransky, E, de Silva, R, Smith, C, Spencer, C, Stefansson, H, Steinberg, S, Stockton, J, Strange, A, Su, Z, Talbot, K, Tanner, C, Tashakkori-Ghanbaria, A, Tison, F, Trabzuni, D, Traynor, B, Uitterlinden, A, Vandrovcova, J, Velseboer, D, Vidailhet, M, Vukcevic, D, Walker, R, van de Warrenburg, B, Weale, M, Wickremaratchi, M, Williams, N, Williams-Gray, C, Winder-Rhodes, S, Stefansson, K, Martinez, M, Donnelly, P, Singleton, AB, Hardy, J, Heutink, P, Brice, A, Gasser, T, Wood, N, WTCCC2

Adapting nanobody scaffolds as protein chaperones for effective crystallization and good protein behaviour in cryo-EM by Ye, M

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