Manolis Kellis
Manolis Kellis (; born 1977) is a professor of Computer Science and Computational Biology at the Massachusetts Institute of Technology (MIT) and a member of the Broad Institute of MIT and Harvard. He is the head of the Computational Biology Group at MIT and is a Principal Investigator in the Computer Science and Artificial Intelligence Lab (CSAIL) at MIT.Kellis is known for his contributions to genomics, human genetics, epigenomics, gene regulation, genome evolution, disease mechanism, and single-cell genomics. He co-led the NIH Roadmap Epigenomics Project effort to create a comprehensive map of the human epigenome, the comparative analysis of 29 mammals to create a comprehensive map of conserved elements in the human genome, the ENCODE, GENCODE, and modENCODE projects to characterize the genes, non-coding elements, and circuits of the human genome and model organisms. A major focus of his work is understanding the effects of genetic variations on human disease, with contributions to obesity, diabetes, Alzheimer's disease, schizophrenia, and cancer. Provided by Wikipedia
Showing 181 - 200 results of 221 for search 'Kellis, Manolis', query time: 0.05s
Refine Results
-
181
A User's Guide to the Encyclopedia of DNA Elements (ENCODE) by Bernstein, Bradley E., Epstein, Charles B., Shoresh, Noam, Ernst, Jason, Mikkelsen, Tarjei Sigurd, Kheradpour, Pouya, Zhang, Xiaolan, Wang, Li, Issner, Robbyn, Coyne, Michael J., Durham, Timothy, Ku, Manching, Truong, Thanh, Ward, Lucas D., Altshuler, Robert Charles, Lin, Michael F., Kellis, Manolis, ENCODE Project Consortium
Published 2011
Get full text
Get full text
Get full text
Article -
182
Unlocking the Secrets of the Genome by Celniker, Susan E., Dillon, Laura A. L., Gerstein, Mark B., Gunsalus, Kristin C., Henikoff, Steven, Karpen, Gary H., Kellis, Manolis, Lai, Eric C., Lieb, Jason D., MacAlpine, David M., Micklem, Gos, Piano, Fabio, Snyder, Michael, Stein, Lincoln, White, Kevin P., Waterston, Robert H.
Published 2012
Article -
183
The Tasmanian Devil Transcriptome Reveals Schwann Cell Origins of a Clonally Transmissible Cancer by Murchison, Elizabeth P., Tovar, Cesar, Hsu, Arthur, Bender, Hannah S., Kheradpour, Pouya, Rebbeck, Clare A., Obendorf, David, Conlan, Carly, Bahlo, Melanie, Blizzard, Catherine A., Pyecroft, Stephen, Kreiss, Alexandre, Kellis, Manolis, Stark, Alexander, Harkins, Timothy T., Graves, Jennifer A. Marshall, Woods, Gregory M., Hannon, Gregory J., Papenfuss, Anthony T.
Published 2014
Article -
184
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans by Claussnitzer, Melina, Dankel, Simon N., Kim, Kyoung-Han, Quon, Gerald, Meuleman, Wouter, Haugen, Christine, Glunk, Viktoria, Sousa, Isabel S., Beaudry, Jacqueline L., Puviindran, Vijitha, Liu, Jannel, Svensson, Per-Arne, Hsu, Yi-Hsiang, Drucker, Daniel J., Mellgren, Gunnar, Hui, Chi-Chung, Hauner, Hans, Kellis, Manolis, Abdennur, Nezar Alexander
Published 2016
Get full text
Get full text
Get full text
Get full text
Article -
185
Survey of variation in human transcription factors reveals prevalent DNA binding changes by Vedenko, A., Kurland, J. V., Rogers, J. M., Gisselbrecht, S. S., Woodard, J., Mariani, L., Kock, K. H., Inukai, S., Siggers, T., Shokri, L., Gordan, R., Sahni, N., Cotsapas, C., Hao, T., Yi, S., Vidal, M., Hill, D. E., Barrera, Luis Alberto, Rossin, Elizabeth, Kellis, Manolis, Daly, Mark J., Bulyk, Martha L.
Published 2017
Get full text
Article -
186
Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity by Shim, Woo Jun, Sinniah, Enakshi, Xu, Jun, Vitrinel, Burcu, Alexanian, Michael, Andreoletti, Gaia, Shen, Sophie, Sun, Yuliangzi, Balderson, Brad, Boix, Carles, Peng, Guangdun, Jing, Naihe, Wang, Yuliang, Kellis, Manolis, Tam, Patrick P.L., Smith, Aaron, Piper, Michael, Christiaen, Lionel, Nguyen, Quan, Bodén, Mikael, Palpant, Nathan J.
Published 2022
Article -
187
An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells by Zhang, Zhizhuo, Chng, Kern Rei, Lingadahalli, Shreyas, Chen, Zikai, Liu, Mei Hui, Do, Huy Hoang, Cai, Shaojiang, Rinaldi, Nicola, Poh, Huay Mei, Li, Guoliang, Sung, Ying Ying, Heng, Charlie L., Core, Leighton J., Tan, Si Kee, Ruan, Xiaoan, Lis, John T., Kellis, Manolis, Ruan, Yijun, Sung, Wing-Kin, Cheung, Edwin
Published 2020
Article -
188
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy by Kousi, Maria, Söylemez, Onuralp, Ozanturk, Aysegül, Mourtzi, Niki, Akle, Sebastian, Jungreis, Irwin, Muller, Jean, Cassa, Christopher A, Brand, Harrison, Mokry, Jill Anne, Wolf, Maxim Y, Sadeghpour, Azita, McFadden, Kelsey, Lewis, Richard A, Talkowski, Michael E, Dollfus, Hélène, Kellis, Manolis, Davis, Erica E, Sunyaev, Shamil R, Katsanis, Nicholas
Published 2021
Article -
189
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy by Kousi, Maria, Söylemez, Onuralp, Ozanturk, Aysegül, Mourtzi, Niki, Akle, Sebastian, Jungreis, Irwin, Muller, Jean, Cassa, Christopher A, Brand, Harrison, Mokry, Jill Anne, Wolf, Maxim Y., Sadeghpour, Azita, McFadden, Kelsey, Lewis, Richard A, Talkowski, Michael E, Dollfus, Hélène, Kellis, Manolis, Davis, Erica E, Sunyaev, Shamil R, Katsanis, Nicholas
Published 2022
Article -
190
Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster by Slattery, Matthew, Ma, Lijia, Spokony, Rebecca F., Arthur, Robert K., Kheradpour, Pouya, Kundaje, Anshul, Negre, Nicolas, Crofts, Alex, Ptashkin, Ryan, Zieba, Jennifer, Ostapenko, Alexander, Suchy, Sarah, Victorsen, Alec, Jameel, Nader, Grundstad, A. Jason, Gao, Wenxuan, Moran, Jennifer R., Rehm, E. Jay, Grossman, Robert L., Kellis, Manolis, White, Kevin P.
Published 2014
Article -
191
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments by Lopes, Noella, McIntyre, Claire, Martin, Stefania, Raverdeau, Mathilde, Sumaria, Nital, Kohlgruber, Ayano C, Fiala, Gina J, Agudelo, Leandro Z, Dyck, Lydia, Kane, Harry, Douglas, Aaron, Cunningham, Stephen, Prendeville, Hannah, Loftus, Roisin, Carmody, Colleen, Pierre, Philippe, Kellis, Manolis, Brenner, Michael, Argüello, Rafael J, Silva-Santos, Bruno, Pennington, Daniel J, Lynch, Lydia
Published 2022
Article -
192
Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures by Wang, Xinchen, Rizki, Gizem, Mills, Robert, de Wit, Elzo, Subramanian, Vidya, Nguyen, Xinh-Xinh, Ye, Jiangchuan, Leyton-Mange, Jordan, van der Harst, Pim, de Laat, Wouter, Newton-Cheh, Christopher, Kellis, Manolis, Tucker, Nathan R., Krijger, Peter H. L., Bartell, Eric R., Dolmatova, Elena V., Ellinor, Patrick T., Milan, David J., Boyer, Laurie Ann
Published 2016
Get full text
Get full text
Article -
193
Dynamics of the Epigenetic Landscape During Erythroid Differentiation after Gata1 Restoration by Wu, Weisheng, Cheng, Yong, Keller, Cheryl A., Ernst, Jason, Kumar, Swathi Ashok, Mishra, Tejaswini, Morrissey, Christapher, Dorman, Christine M., Chen, Kuan-Bei, Drautz, Daniela, Giardine, Belinda, Shibata, Yoichiro, Song, Lingyun, Pimkin, Max, Crawford, Gregory E., Furey, Terrence S., Kellis, Manolis, Miller, Webb, Taylor, James, Schuster, Stephan C., Zhang, Yu, Chiaromonte, Francesca, Blobel, Gerd A., Weiss, Mitchell J., Hardison, Ross C.
Published 2012
Article -
194
Histone Modifications at Human Enhancers Reflect Global Cell-Type-Specific Gene Expression by Heintzman, Nathaniel D., Hon, Gary C., Hawkins, R. David, Kheradpour, Pouya, Stark, Alexander, Harp, Lindsey F., Ye, Zhen, Lee, Leonard K., Stuart, Rhona K., Ching, Christina W., Ching, Keith A., Antosiewicz-Bourget, Jessica E., Liu, Hui, Zhang, Xinmin, Green, Roland D., Lobanenkov, Victor V., Stewart, Ron, Thomson, James A., Crawford, Gregory E., Kellis, Manolis, Ren, Bing
Published 2012
Article -
195
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters by Hung, Tiffany, Wang, Yulei, Lin, Michael F., Koegel, Ashley K., Kotake, Yojiro, Grant, Gavin D., Horlings, Hugo M., Shah, Nilay, Umbricht, Christopher, Wang, Pei, Wang, Yu, Kong, Benjamin, Langerød, Anita, Børresen-Dale, Anne-Lise, Kim, Seung K., van de Vijver, Marc, Sukumar, Saraswati, Whitfield, Michael L., Kellis, Manolis, Xiong, Yue, Wong, David J., Chang, Howard Y., Lin, Michael F.
Published 2014
Article -
196
Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells by Lee, M. N., Ye, C., Villani, A.-C., Raj, T., Li, W., Eisenhaure, Thomas, Imboywa, S. H., Chipendo, P. I., Slowikowski, K., Raddassi, K., McCabe, C., Lee, M. H., Frohlich, I. Y., Raychaudhuri, S., Stranger, B. E., Benoist, Christophe, De Jager, Philip L., Hacohen, Nir, Ran, F. Ann, Zhang, Feng, Regev, Aviv, Hafler, David A., Ward, Lucas D., Kellis, Manolis
Published 2015
Get full text
Get full text
Get full text
Article -
197
Integrative analysis of 111 reference human epigenomes by Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Yen, Angela, Kheradpour, Pouya, Zhang, Zhizhuo, Wang, Jianrong, Ward, Lucas D., Sarkar, Abhishek Kulshreshtha, Quon, Gerald, Eaton, Matthew Lucas, Wu, Yi-Chieh, Pfenning, Andreas R., Wang, Xinchen, Claussnitzer, Melina, Liu, Yaping, Bansal, Mukul S., Kim, Ah Ram, Cowper Sal-lari, Richard, Sinnott-Armstrong, Nicholas A., Gjoneska, Elizabeta, Tsai, Li-Huei, Kellis, Manolis, Feizi- Khankandi, Soheil, Boyer, Laurie Ann
Published 2016
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Article -
198
Intermediate DNA methylation is a conserved signature of genome regulation by Elliott, GiNell, Hong, Chibo, Xing, Xiaoyun, Zhou, Xin, Li, Daofeng, Coarfa, Cristian, Bell, Robert J.A., Maire, Cecile L., Ligon, Keith L., Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea D., Harris, R. Alan, Schalkwyk, Leonard C., Bilenky, Misha, Mill, Jonathan, Farnham, Peggy J., Kellis, Manolis, Marra, Marco A., Milosavljevic, Aleksandar, Hirst, Martin, Stormo, Gary D., Wang, Ting, Costello, Joseph F.
Published 2018
Article -
199
Multiple knockout mouse models reveal lincRNAs are required for life and brain development by Goff, Loyal, Kellis, Manolis, Sauvageau, Martin, Lodato, Simona, Bonev, Boyan, Groff, Abigail F., Gerhardinger, Chiara, Sanchez-Gomez, Diana B., Hacisuleyman, Ezgi, Li, Eric, Spence, Matthew, Liapis, Stephen C., Mallard, William, Morse, Michael, Swerdel, Mavis R., D'Ecclessis, Michael F., Moore, Jennifer C., Lai, Venus, Gong, Guochun, Yancopoulos, George D., Frendewey, David, Hart, Ronald P., Valenzuela, David M., Arlotta, Paola, Rinn, John L.
Published 2014
Article -
200
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers by Onengut-Gumuscu, Suna, Chen, Wei-Min, Burren, Oliver, Farber, Emily, Szpak, Michal, Schofield, Ellen, Achuthan, Premanand, Guo, Hui, Stevens, Helen, Kundaje, Anshul, Kellis, Manolis, Deloukas, Panos, Wallace, Chris, Concannon, Patrick, Cooper, Nick J., Quinlan, Aaron R., Mychaleckyj, Josyf C., Bonnie, Jessica K., Fortune, Mary D., Walker, Neil M., Ward, Lucas D., Daly, Mark J., Barrett, Jeffrey C., Cooper, Jason D., Todd, John A., Rich, Stephen S.
Published 2016
Get full text
Article