Manolis Kellis
Manolis Kellis (; born 1977) is a professor of Computer Science and Computational Biology at the Massachusetts Institute of Technology (MIT) and a member of the Broad Institute of MIT and Harvard. He is the head of the Computational Biology Group at MIT and is a Principal Investigator in the Computer Science and Artificial Intelligence Lab (CSAIL) at MIT.Kellis is known for his contributions to genomics, human genetics, epigenomics, gene regulation, genome evolution, disease mechanism, and single-cell genomics. He co-led the NIH Roadmap Epigenomics Project effort to create a comprehensive map of the human epigenome, the comparative analysis of 29 mammals to create a comprehensive map of conserved elements in the human genome, the ENCODE, GENCODE, and modENCODE projects to characterize the genes, non-coding elements, and circuits of the human genome and model organisms. A major focus of his work is understanding the effects of genetic variations on human disease, with contributions to obesity, diabetes, Alzheimer's disease, schizophrenia, and cancer. Provided by Wikipedia
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141
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis by Carlevaro-Fita, Joana, Lanzós, Andrés, Feuerbach, Lars, Hong, Chen, Mas-Ponte, David, Pedersen, Jakob Skou, Johnson, Rory, Kellis, Manolis, PCAWG Drivers and Functional Interpretation Group
Published 2021
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142
A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane by Guillén-Samander, Andrés, Wu, Yumei, Pineda, S Sebastian, García, Francisco J, Eisen, Julia N, Leonzino, Marianna, Ugur, Berrak, Kellis, Manolis, Heiman, Myriam, De Camilli, Pietro
Published 2023
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143
The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse by Grote, Phillip, Wittler, Lars, Hendrix, David A., Koch, Frederic, Beisaw, Arica, Macura, Karol, Kellis, Manolis, Werber, Martin, Herrmann, Bernhard G., Wahrisch, Sandra, Blass, Gaby
Published 2014
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144
Soft X-Ray Tomography Reveals Gradual Chromatin Compaction and Reorganization during Neurogenesis In Vivo by Le Gros, Mark A., Clowney, E. Josephine, Magklara, Angeliki, Yen, Angela, Markenscoff-Papadimitriou, Eirene, Colquitt, Bradley, Myllys, Markko, Kellis, Manolis, Lomvardas, Stavros, Larabell, Carolyn A.
Published 2017
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145
Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes by Miyamoto, Kei, Allen, George E., Jullien, Jerome, Otani, Tomoki, Bradshaw, Charles R., Livesey, Frederick J., Gurdon, John B., Nguyen, Khoi Thien, Kumar, Dinesh, Kellis, Manolis
Published 2018
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147
An integrated encyclopedia of DNA elements in the human genome by Altshuler, Robert Charles, Ernst, Jason, Kellis, Manolis, Kheradpour, Pouya, Ward, Lucas D., Eaton, Matthew Lucas, Hendrix, David A., Jungreis, Irwin, Lin, Michael F., Washietl, Stefan
Published 2014
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148
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival by Hornshøj, Henrik, Nielsen, Morten Muhlig, Sinnott-Armstrong, Nicholas A., Świtnicki, Michał P., Juul, Malene, Madsen, Tobias, Sallari, Richard, Kellis, Manolis, Ørntoft, Torben, Hobolth, Asger, Pedersen, Jakob Skou
Published 2020
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149
Alternatives to amyloid for Alzheimer's disease therapies—a symposium report by Cable, Jennifer, Holtzman, David M., Hyman, Bradley T., Tansey, Malú Gámez, Colonna, Marco, Kellis, Manolis, Brinton, Roberta D., Albert, Marilyn, Wellington, Cheryl L., Sisodia, Sangram S., Tanzi, Rudolph E.
Published 2021
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150
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble by Marco, Asaf, Meharena, Hiruy S., Dileep, Vishnu, Raju, Ravikiran M., Davila Velderrain, Jose, Zhang, Amy Letao, Adaikkan, Chinnakkaruppan, Young, Jennie Zin-Ney, Gao, Fan, Kellis, Manolis, Tsai, Li-Huei
Published 2021
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151
Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution by Jungreis, Irwin, Nelson, Chase W., Ardern, Zachary, Finkel, Yaara, Krogan, Nevan J., Sato, Kei, Ziebuhr, John, Stern-Ginossar, Noam, Pavesi, Angelo, Firth, Andrew E., Gorbalenya, Alexander E., Kellis, Manolis
Published 2021
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152
High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic by Gire, Stephen, Ellis, Crystal, Calderwood, Stephen B., Qadri, Firdausi, Hensley, Lisa E., Kellis, Manolis, Ryan, Edward T., LaRocque, Regina C., Harris, Jason B., Sabeti, Pardis C., Sealfon, Rachel Sima
Published 2012
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153
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs by McCorkindale, Alexandra L., Wahle, Philipp, Werner, Sascha, Jungreis, Irwin, Menzel, Peter, Shukla, Chinmay J., Abreu, Rúben Lopes Pereira, Irizarry, Rafael A., Meyer, Irmtraud M., Kellis, Manolis, Zinzen, Robert P.
Published 2020
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154
An Epigenetic Signature for Monoallelic Olfactory Receptor Expression by Magklara, Angeliki, Yen, Angela, Colquitt, Bradley M., Clowney, E. Josephine, Allen, William, Markenscoff-Papadimitriou, Eirene, Evans, Zoe A., Kheradpour, Pouya, Mountoufaris, George, Carey, Catriona, Barnea, Gilad, Kellis, Manolis, Lomvardas, Stavros
Published 2014
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155
Rapid dissection and model-based optimization of inducible enhancers in human cells using a massively parallel reporter assay by Melnikov, Alexandre, Murugan, Anand, Zhang, Xiaolan, Tesileanu, Tiberiu, Wang, Li, Rogov, Peter, Feizi-Khankandi, Soheil, Gnirke, Andreas, Callan Jr, Curtis G., Kinney, Justin B., Kellis, Manolis, Lander, Eric S., Mikkelsen, Tarjei Sigurd, 1978-
Published 2012
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156
Evolutionary principles of modular gene regulation in yeasts by Thompson, Dawn A., Roy, Sushmita, Chan, Michelle Mei Wah, Styczynsky, Mark P., Pfiffner, Jenna, French, Courtney, Socha, Amanda, Thielke, Anne, Napolitano, Sara, Muller, Paul, Kellis, Manolis, Konieczka, Jay, Wapinski, Ilan, Regev, Aviv
Published 2014
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157
Mapping and Analysis of Chromatin State Dynamics in Nine Human Cell Types by Ernst, Jason, Kheradpour, Pouya, Mikkelsen, Tarjei Sigurd, Shoresh, Noam, Ward, Lucas D., Epstein, Charles B., Zhang, Xiaolan, Wang, Li, Issner, Robbyn, Coyne, Michael J., Ku, Manching, Durham, Timothy, Kellis, Manolis, Bernstein, Bradley E.
Published 2012
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158
Co-expression networks reveal the tissue-specific regulation of transcription and splicing by Saha, Ashis, Kim, Yungil, Gewirtz, Ariel D.H., Jo, Brian, Gao, Chuan, McDowell, Ian C., The GTEx Consortium, Engelhardt, Barbara E., Battle, Alexis, Hou, Lei, Kellis, Manolis, Liu, Yaping, Park, YongJin, Rinaldi, Nicola
Published 2022
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Single-cell dissection of the human brain vasculature by Garcia, Francisco J, Sun, Na, Lee, Hyeseung, Godlewski, Brianna, Mathys, Hansruedi, Galani, Kyriaki, Zhou, Blake, Jiang, Xueqiao, Ng, Ayesha P, Mantero, Julio, Tsai, Li-Huei, Bennett, David A, Sahin, Mustafa, Kellis, Manolis, Heiman, Myriam
Published 2022
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Integrative annotation of chromatin elements from ENCODE data by Ernst, Jason, Kellis, Manolis, Hoffman, Michael M., Wilder, Steven P., Kundaje, Anshul, Harris, Robert S., Libbrecht, Max, Giardine, Belinda, Ellenbogen, Paul M., Bilmes, Jeffrey A., Birney, Ewan, Hardison, Ross C., Dunham, Ian, Noble, William Stafford
Published 2013
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