A nanoluciferase SFTSV for rapid screening antivirals and real-time visualization of virus infection in miceResearch in context by Huan Xu, Xiaoqin Jian, Yuxi Wen, Mengwei Xu, Runming Jin, Xiaoyan Wu, Fen Zhou, Junyuan Cao, Gengfu Xiao, Ke Peng, Yuanchao Xie, Hongbo Chen, Leike Zhang

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Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth by Hsuan-Yuan Wang, Leike Li, Cody S. Nelson, Richard Barfield, Sarah Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J. C. Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R. Permar

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A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial by Leike Li, Daniel C. Freed, Yaping Liu, Fengsheng Li, Diane F. Barrett, Wei Xiong, Xiaohua Ye, Stuart P. Adler, Richard E. Rupp, Dai Wang, Ningyan Zhang, Tong-Ming Fu, Zhiqiang An

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Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection by Sarah M. Valencia, Eric Rochat, Melissa J. Harnois, Maria Dennis, Helen S. Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan (Sherry) Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R. Permar

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Comparison of the Fungal Community, Chemical Composition, Antioxidant Activity, and Taste Characteristics of Fu Brick Tea in Different Regions of China by Yulian Chen, Yulian Chen, Jiaxu Chen, Jiaxu Chen, Ruyang Chen, Leike Xiao, Xing Wu, Lin Hu, Zongjun Li, Yuanliang Wang, Mingzhi Zhu, Mingzhi Zhu, Zhonghua Liu, Zhonghua Liu, Yu Xiao, Yu Xiao

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A 3D View of Orion. I. Barnard's Loop by Michael M. Foley, Alyssa Goodman, Catherine Zucker, John C. Forbes, Ralf Konietzka, Cameren Swiggum, João Alves, John Bally, Juan D. Soler, Josefa E. Großschedl, Shmuel Bialy, Michael Y. Grudić, Reimar Leike, Torsten Enßlin

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Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo-controlled, phase 1b trialResearch in context by Fuxiang Wang, Wen Xiao, Yimin Tang, Mengli Cao, Dan Shu, Tetsuya Asakawa, Yechun Xu, Xiangrui Jiang, Leike Zhang, Wei Wang, Jianxing Tang, Yuansheng Huang, Yang Yang, Yumei Yang, Renhong Tang, Jingshan Shen, Hongzhou Lu

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LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions by Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

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Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment by Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju

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Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir by Xiangrui Jiang, Haixia Su, Weijuan Shang, Feng Zhou, Yan Zhang, Wenfeng Zhao, Qiumeng Zhang, Hang Xie, Lei Jiang, Tianqing Nie, Feipu Yang, Muya Xiong, Xiaoxing Huang, Minjun Li, Ping Chen, Shaoping Peng, Gengfu Xiao, Hualiang Jiang, Renhong Tang, Leike Zhang, Jingshan Shen, Yechun Xu

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Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry by Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke Guddat, Hongli Chen, Leike Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang

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Magnetic-driven hydrogel microrobots for promoting osteosarcoma chemo-therapy with synthetic lethality strategy by Yining Tao, Yining Tao, Leike Li, Xiyu Yang, Xiyu Yang, Shiyu Yin, Shiyu Yin, Zhanxiang Zhang, Haoyu Wang, Haoyu Wang, Ruochen Pu, Ruochen Pu, Zongyi Wang, Zongyi Wang, Qi Zhang, Haoran Mu, Haoran Mu, Chenqiong Wu, Jin He, Jin He, Liu Yang, Liu Yang

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A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates by Chang Guo, Yanan Peng, Lin Lin, Xiaoyan Pan, Mengqi Fang, Yun Zhao, Keyan Bao, Runhan Li, Jianbao Han, Jiaorong Chen, Tian-Zhang Song, Xiao-Li Feng, Yahong Zhou, Gan Zhao, Leike Zhang, Yongtang Zheng, Ping Zhu, Haiying Hang, Linqi Zhang, Zhaolin Hua, Hongyu Deng, Baidong Hou

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Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 by Rui Xiong, Leike Zhang, Shiliang Li, Yuan Sun, Minyi Ding, Yong Wang, Yongliang Zhao, Yan Wu, Weijuan Shang, Xiaming Jiang, Jiwei Shan, Zihao Shen, Yi Tong, Liuxin Xu, Yu Chen, Yingle Liu, Gang Zou, Dimitri Lavillete, Zhenjiang Zhao, Rui Wang, Lili Zhu, Gengfu Xiao, Ke Lan, Honglin Li, Ke Xu

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Repurposing of Rutan showed effective treatment for COVID-19 disease by Shavkat I. Salikhov, Ibrokhim Y. Abdurakhmonov, Yuliya I. Oshchepkova, Jamolitdin F. Ziyavitdinov, Nodir Sh. Berdiev, Haji Akber Aisa, Jingshan Shen, Yechun Xu, H. Eric Xu, Xiangrui Jiang, Leike Zhang, Natalia L. Vypova, Dilshod Sh. Allaberganov, Nigora A. Tagayalieva, Erkin I. Musabaev, Gulnara A. Ibadova, Ilxom B. Rajabov, Lyubov M. Lokteva

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Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 by Rui Xiong, Leike Zhang, Shiliang Li, Yuan Sun, Minyi Ding, Yong Wang, Yongliang Zhao, Yan Wu, Weijuan Shang, Xiaming Jiang, Jiwei Shan, Zihao Shen, Yi Tong, Liuxin Xu, Yu Chen, Yingle Liu, Gang Zou, Dimitri Lavillete, Zhenjiang Zhao, Rui Wang, Lili Zhu, Gengfu Xiao, Ke Lan, Honglin Li, Ke Xu

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Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 by Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Gengfu Xiao, Zihe Rao, Lu Lu, Leike Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu

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