Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics by Fernandez-Mercado, M, Yip, B, Pellagatti, A, Davies, C, Larrayoz, M, Kondo, T, Pérez, C, Killick, S, McDonald, E, Odero, MD, Agirre, X, Prósper, F, Calasanz, M, Wainscoat, J, Boultwood, J

PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia by Chase, A, Pellagatti, A, Singh, S, Score, J, Tapper, W, Lin, F, Hoade, Y, Bryant, C, Trim, N, Yip, B, Zoi, K, Rasi, C, Forsberg, L, Dumanski, J, Boultwood, J, Cross, N

Differential expression of genes related to JAK-STAT pathway activation or megakaryocyte differentiation/maturation in CD34+cells from patients with refractory anemia with ringed s... by Malcovati, L, Pietra, D, Della Porta, MG, Pellagatti, A, Travaglino, E, Boveri, E, Galli, A, Rumi, E, Passamonti, F, Cremonesi, L, Invenizzi, R, Boultwood, J, Hellstroem-Lindberg, E, Wainscoat, J, Cazzola, M

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts by Boultwood, J, Pellagatti, A, Nikpour, M, Pushkaran, B, Fidler, C, Cattan, H, Littlewood, T, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Giagounidis, A, Bowen, D, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J

Phospholipase C beta1 (PI-PLCbeta1)/Cyclin D3/protein kinase C (PKC) alpha signaling modulation during iron-induced oxidative stress in myelodysplastic syndromes (MDS) by Cappellini, A, Mongiorgi, S, Finelli, C, Fazio, A, Ratti, S, Marvi, MV, Curti, A, Salvestrini, V, Pellagatti, A, Billi, AM, Suh, P-G, McCubrey, JA, Boultwood, J, Manzoli, L, Cocco, L, Follo, MY

Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1 mutant myelodysplastic syndromes by Dolatshad, H, Repapi, E, Steeples, V, Roy, S, Scifo, L, Armstrong, R, Shaw, J, Yip, B, Taylor, S, Boultwood, J, Liberante, F, Llorian, M, Killick, S, Kusec, R, Mills, K, Savage, K, Smith, C, Pellagatti, A

COMPREHENSIVE ANALYSIS OF MUTATION STATUS, GENE EXPRESSION PROFILES, BLOOD AND BONE MARROW COUNTS AND OUTCOME IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES by Pellagatti, A, Gerstung, M, Papaemmanuil, E, Malcovati, L, Giagounidis, A, Della Porta, MG, Jadersten, M, Dolatshad, H, Verma, A, Cross, N, Vyas, P, Killick, S, Hellstrom-Lindberg, E, Cazzola, M, Campbell, P, Boultwood, J

Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS. by Keerthivasan, G, Mei, Y, Zhao, B, Zhang, L, Harris, C, Gao, J, Basiorka, A, Schipma, M, McElherne, J, Yang, J, Verma, A, Pellagatti, A, Boultwood, J, List, A, Williams, D, Ji, P

Progression in patients with low- and intermediate1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations. by Scharenberg, C, Giai, V, Pellagatti, A, Saft, L, Dimitriou, M, Jansson, M, Jädersten, M, Grandien, A, Douagi, I, Neuberg, D, LeBlanc, K, Boultwood, J, Karimi, M, Jacobsen, S, Woll, P, Hellström-Lindberg, E

Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes. by Pellagatti, A, Benner, A, Mills, K, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Verma, A, McDonald, E, Killick, S, Hellström-Lindberg, E, Bullinger, L, Wainscoat, J, Boultwood, J

Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. by Malcovati, L, Della Porta, MG, Pietra, D, Boveri, E, Pellagatti, A, Gallì, A, Travaglino, E, Brisci, A, Rumi, E, Passamonti, F, Invernizzi, R, Cremonesi, L, Boultwood, J, Wainscoat, J, Hellström-Lindberg, E, Cazzola, M

Gene expression and risk of leukemic transformation in myelodysplasia by Shiozawa, Y, Malcovati, L, Gallì, A, Pellagatti, A, Karimi, M, Sato-Otsubo, A, Sato, Y, Suzuki, H, Yoshizato, T, Yoshida, K, Shiraishi, Y, Chiba, K, Makishima, H, Boultwood, J, Hellström-Lindberg, E, Miyano, S, Cazzola, M, Ogawa, S

Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability. by Savage, K, Gorski, J, Barros, E, Irwin, G, Manti, L, Powell, A, Pellagatti, A, Lukashchuk, N, McCance, D, McCluggage, W, Schettino, G, Salto-Tellez, M, Boultwood, J, Richard, D, McDade, S, Harkin, D

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia. by Boultwood, J, Perry, J, Pellagatti, A, Fernandez-Mercado, M, Fernandez-Santamaria, C, Calasanz, M, Larrayoz, M, Garcia-Delgado, M, Giagounidis, A, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J

Identification of aberrant splicing events in myelodysplastic syndrome patients with splicing factor gene mutations by Pellagatti, A, Steeples, V, Sharma, E, Repapi, E, Yip, B, Armstrong, R, Dolatshad, H, Lockstone, H, Taylor, S, Giagounidis, A, Vyas, P, Papaemmanuil, E, Woll, P, Killick, S, Malcovati, L, Hellstrom-Lindberg, E, Cazzola, M, Smith, C, Boultwood, J

Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q by Adema, V, Palomo, L, Walter, W, Mallo, M, Hutter, S, La Framboise, T, Arenillas, L, Meggendorfer, M, Radivoyevitch, T, Xicoy, B, Pellagatti, A, Haferlach, C, Boultwood, J, Kern, W, Visconte, V, Sekeres, M, Barnard, J, Haferlach, T, Solé, F, Maciejewski, JP

Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline by Hennrich, M, Romanov, N, Horn, P, Jaeger, S, Eckstein, V, Steeples, V, Ye, F, Ding, X, Poisa-Beiro, L, Lai, M, Lang, B, Boultwood, J, Luft, T, Zaugg, J, Pellagatti, A, Bork, P, Aloy, P, Gavin, A, Ho, A

Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes by Follo, M, Pellagatti, A, Armstrong, R, Ratti, S, Mongiorgi, S, De Fanti, S, Bochicchio, M, Russo, D, Gobbi, M, Miglino, M, Parisi, S, Martinelli, G, Cavo, M, Luiselli, D, McCubrey, J, Suh, P, Manzoli, L, Boultwood, J, Finelli, C, Cocco, L

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes. by Yip, B, Steeples, V, Repapi, E, Armstrong, R, Llorian, M, Roy, S, Shaw, J, Dolatshad, H, Taylor, S, Verma, A, Bartenstein, M, Vyas, P, Cross, N, Malcovati, L, Cazzola, M, Hellström-Lindberg, E, Ogawa, S, Smith, C, Pellagatti, A, Boultwood, J

High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potent... by Papaemmanuil, E, Gerstung, M, Malcovati, L, Tauro, S, Gundem, G, Van Loo, P, Pellagatti, A, Groves, M, Cross, N, Gambacorti-Passerini, C, Green, A, Boultwood, J, Vyas, P, Hellstrom-Lindberg, E, Bowen, D, Cazzola, M, Stratton, MR, Campbell, P