Smoking induces increased apoptosis in osteoblasts: changes in bone matrix organic components by Júlia Benini Kohler, Alex Ferreira da Silva, Walleson Alves Farias, Barbara Fialho Carvalho Sampaio, Marco Aurélio Silveiro Neves, Leandro Gregorut Lima, Juliana Dias Lourenço, Alyne Riani Moreira, Alexandre Póvoa Barbosa, Iolanda de Fátima Lopes Calvo Tibério, Walcy Rosolia Teodoro, Fernanda Degobbi Tenorio Quirino dos Santos Lopes

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Factors associated with uncontrolled blood pressure in hypertensive Brazilians by Thayza de Paula Araújo, Lucas Gabriel Sulino Borges, Weimar Kunz Sebba Barroso, Andrea Araújo Brandão, Eduardo Costa Duarte Barbosa, Audes Diógenes M Feitosa, Marcus Vinícius Bolivar Malachias, Marco Mota Gomes, Celso Amodeo, Rui Manoel dos Santos Povoa, Paulo César Brandão Veiga Jardim, Renato D. Lopes, Sandro Rogério Rodrigues Batista, Priscila Valverde de Oliveira Vitorino, the researchers of Study I RBH

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Metrics of care and cardiovascular outcomes in patients with ST-elevation myocardial infarction treated with pharmacoinvasive strategy: a decade-long network in a populous city in... by Pedro Ivo De Marqui Moraes, Attilio Galhardo, Adriano Henrique Pereira Barbosa, Jose Marconi Almeida de Sousa, Claudia Maria Rodrigues Alves, Henrique Tria Bianco, Rui Manuel dos Santos Povoa, Edson Stefanini, Iran Goncalves, Dirceu Rodrigues de Almeida, Francisco Antonio Helfenstein Fonseca, Maria Cristina de Oliveira Izar, Valdir Ambrosio Moises, Renato Delascio Lopes, Antonio Carlos Carvalho, Adriano Caixeta

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Pharmacological Modulation by Low Molecular Weight Heparin of Purinergic Signaling in Cardiac Cells Prevents Arrhythmia and Lethality Induced by Myocardial Infarction by Carlos Eduardo Braga Filho, Adriano Henrique Pereira Barbosa, Lucas Antonio Duarte Nicolau, Jand Venes Rolim Medeiros, Marcelo Pires-Oliveira, Rui Manuel dos Santos Póvoa, Tânia Carmen Penãranda Govato, Hézio Jadir Fernandes Júnior, Rafael Guzella de Carvalho, Bráulio Luna-Filho, Fernando Sabia Tallo, Erisvaldo Amarante de Araújo, José Gustavo Padrão Tavares, Ricardo Mario Arida, Afonso Caricati-Neto, Francisco Sandro Menezes-Rodrigues

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Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study by Greco, M, De Corte, T, Ercole, A, Antonelli, M, Azoulay, E, Citerio, G, Morris, AC, De Pascale, G, Duska, F, Elbers, P, Einav, S, Forni, L, Galarza, L, Girbes, ARJ, Grasselli, G, Gusarov, V, Jubb, A, Kesecioglu, J, Lavinio, A, Delgado, MCM, Mellinghoff, J, Myatra, SN, Ostermann, M, Pellegrini, M, Povoa, P, Schaller, SJ, Teboul, J-L, Wong, A, De Waele, JJ, Cecconi, M, Nichol, A

Implementation of basic quality control tests for malaria medicines in Amazon Basin countries: results for the 2005–2010 period by Pribluda Victor S, Barojas Adrian, Añez Arletta, López Cecilia G, Figueroa Ruth, Herrera Roxana, Nakao Gladys, Nogueira Fernando HA, Pianetti Gerson A, Povoa Marinete M, Viana Giselle MR, Gomes Margarete S, Escobar Jose P, Sierra Olga L, Norena Susana P, Veloz Raúl, Bravo Marcy, Aldás Martha R, HindsSemple Alison, Collins Marilyn, Ceron Nicolas, Krishnalall Karanchand, Adhin Malti, Bretas Gustavo, Hernandez Nelly, Mendoza Marjorie, Smine Abdelkrim, Chibwe Kennedy, Lukulay Patrick, Evans Lawrence

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Current challenges in the management of sepsis in ICUs in resource–poor settings and suggestions for the future by Thwaites, C, Schultz, M, Dunser, M, Dondorp, A, Adhikari, N, Iyer, S, Kwizera, A, Lubell, Y, Papali, A, Pisani, L, Riviello, B, Angus, D, Azevedo, L, Baker, T, Diaz, J, Festic, E, Haniffa, R, Jawa, R, Jacob, S, Kissoon, N, Lodha, R, Martin-Loeches, I, Lundeg, G, Misango, D, Mer, M, Mohanty, S, Murthy, S, Musa, N, Nakibuuka, J, Neto, A, Mai, N, Binh, N, Pattnaik, R, Phua, J, Preller, J, Povoa, P, Ranjit, S, Talmor, D, Thevanayagam, J

Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health by Gardiner, E, Baumgart, A, Tong, A, Elliott, JH, Azevedo, LC, Bersten, A, Cervantes, L, Chew, DP, Cho, Y, Crowe, S, Douglas, IS, Evangelidis, N, Flemyng, E, Horby, P, Howell, M, Lee, J, Lorca, E, Lynch, D, Marshall, JC, Gonzalez, AM, McKenzie, A, Manera, K, Mehta, S, Mer, M, Morris, AC, Nseir, S, Povoa, P, Reid, M, Sakr, Y, Shen, N, Smyth, AR, Snelling, T, Strippoli, GFM, Teixeira-Pinto, A, Torres, A, Viecelli, AK, Webb, S, Williamson, PR, Woc-Colburn, L, Zhang, J, Craig, JC

Core outcome measures for trials in people with coronavirus disease 2019: Respiratory failure, multiorgan failure, shortness of breath, and recovery by Tong, A, Baumgart, A, Evangelidis, N, Viecelli, AK, Carter, SA, Azevedo, LC, Cooper, T, Bersten, A, Cervantes, L, Chew, DP, Crowe, S, Douglas, IS, Flemyng, E, Elliott, JH, Hannan, E, Horby, P, Howell, M, Ju, A, Lee, J, Lorca, E, Lynch, D, Manera, KE, Marshall, JC, Gonzalez, AM, McKenzie, A, Mehta, S, Mer, M, Morris, AC, Needham, DM, Nseir, S, Povoa, P, Reid, M, Sakr, Y, Shen, N, Smyth, AR, Simpson, AJ, Snelling, T, Strippoli, GFM, Teixeira-Pinto, A, Torres, A, Turner, T, Webb, S, Williamson, PR, Woc-Colburn, L, Zhang, J, Craig, JC

Thrombophilia and Immune-Related Genetic Markers in Long COVID by Rosilene da Silva, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Flávia Póvoa da Costa, Erika Ferreira dos Santos, Fabíola Brasil Barbosa Rodrigues, Maria de Nazaré do Socorro de Almeida Viana, Mauro de Meira Leite, Andréa Luciana Soares da Silva, Mioni Thieli Magalhães de Brito, Maria Karoliny da Silva Torres, Maria Alice Freitas Queiroz, Izaura Maria Vieira Cayres Vallinoto, Daniele Freitas Henriques, Carla Pinheiro dos Santos, Giselle Maria Rachid Viana, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos

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Antibody Response to the SARS-CoV-2 Spike and Nucleocapsid Proteins in Patients with Different COVID-19 Clinical Profiles by Sinei Ramos Soares, Maria Karoliny da Silva Torres, Sandra Souza Lima, Kevin Matheus Lima de Sarges, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Adriana de Oliveira Lameira Veríssimo, Izaura Maria Vieira Cayres Vallinoto, Rosimar Neris Martins Feitosa, Juarez Antônio Simões Quaresma, Tânia do Socorro Souza Chaves, Giselle Maria Rachid Viana, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto, Andréa Nazaré Monteiro Rangel da Silva

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Core outcomes set for trials in people with coronavirus disease 2019 by Tong, A, Elliott, JH, Azevedo, LC, Baumgart, A, Bersten, A, Cervantes, L, Chew, DP, Cho, Y, Cooper, T, Crowe, S, Douglas, IS, Evangelidis, N, Flemyng, E, Hannan, E, Horby, P, Howell, M, Lee, J, Liu, E, Lorca, E, Lynch, D, Marshall, JC, Gonzalez, AM, McKenzie, A, Manera, KE, McLeod, C, Mehta, S, Mer, M, Morris, AC, Nseir, S, Povoa, P, Reid, M, Sakr, Y, Shen, N, Smyth, AR, Snelling, T, Strippoli, GF, Teixeira-Pinto, A, Torres, A, Turner, T, Viecelli, AK, Webb, S, Williamson, PR, Woc-Colburn, L, Zhang, J, Craig, JC, COVID-19-Core Outcomes Set (COS) Workshop Investigators

Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study by Ouriel Saura, Anahita Rouzé, Ignacio Martin-Loeches, Pedro Povoa, Louis Kreitmann, Antoni Torres, Matthieu Metzelard, Damien Du Cheyron, Fabien Lambiotte, Fabienne Tamion, Marie Labruyere, Claire Boulle Geronimi, Charles-Edouard Luyt, Martine Nyunga, Olivier Pouly, Arnaud W. Thille, Bruno Megarbane, Anastasia Saade, Eleni Magira, Jean-François Llitjos, Iliana Ioannidou, Alexandre Pierre, Jean Reignier, Denis Garot, Jean-Luc Baudel, Guillaume Voiriot, Gaëtan Plantefeve, Elise Morawiec, Pierre Asfar, Alexandre Boyer, Armand Mekontso-Dessap, Fotini Bardaka, Emili Diaz, Christophe Vinsonneau, Pierre-Edouard Floch, Nicolas Weiss, Adrian Ceccato, Antonio Artigas, David Nora, Alain Duhamel, Julien Labreuche, Saad Nseir, coVAPid Study Group

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Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the International Severe Acute Respiratory and Emerging Infection Consortium WHO... by Reyes, LF, Murthy, S, Garcia-Gallo, E, Irvine, M, Merson, L, Martin-Loeches, I, Rello, J, Taccone, FS, Fowler, RA, Docherty, AB, Kartsonaki, C, Aragao, I, Barrett, PW, Beane, A, Burrell, A, Cheng, MP, Christian, MD, Cidade, JP, Citarella, BW, Donnelly, CA, Fernandes, SM, French, C, Haniffa, R, Harrison, EM, Ho, AYW, Joseph, M, Khan, I, Kho, ME, Kildal, AB, Kutsogiannis, D, Lamontagne, F, Lee, TC, Bassi, GL, Lopez Revilla, JW, Marquis, C, Millar, J, Neto, R, Nichol, A, Parke, R, Pereira, R, Poli, S, Povoa, P, Ramanathan, K, Rewa, O, Riera, J, Shrapnel, S, Silva, MJ, Udy, A, Uyeki, T, Webb, SA

International survey to establish prioritized outcomes for trials in people with coronavirus disease 2019 by Evangelidis, N, Tong, A, Howell, M, Teixeira-Pinto, A, Elliott, JH, Azevedo, LC, Bersten, A, Cervantes, L, Chew, DP, Crowe, S, Douglas, IS, Flemyng, E, Horby, P, Lee, J, Lorca, E, Lynch, D, Marshall, JC, McKenzie, A, Mehta, S, Mer, M, Morris, AC, Nseir, S, Povoa, P, Reid, M, Sakr, Y, Shen, N, Smyth, AR, Snelling, T, Strippoli, GFM, Torres, A, Turner, T, Webb, S, Williamson, PR, Woc-Colburn, L, Zhang, J, Baumgart, A, Cabrera, S, Cho, Y, Cooper, T, Guha, C, Liu, E, Gonzalez, AM, McLeod, C, Natale, P, Saglimbene, V, Viecelli, AK, Craig, JC, COVID-19-Core Outcomes Set (COS) Survey Investigators

Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population by Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Maria de Nazaré do Socorro de Almeida Viana, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Igor Brasil Costa, Juliana Abreu Lima Nunes, Iran Barros Costa, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Sandra Souza Lima, Jeferson da Costa Lopes, Maria Karoliny da Silva Torres, Izaura Maria Vieira Cayres Vallinoto, Carlos David Araújo Bichara, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos

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Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19 by Maria Alice Freitas Queiroz, Maria Alice Freitas Queiroz, Angélica Menezes Santiago, Angélica Menezes Santiago, Wandrey Roberto dos Santos Brito, Wandrey Roberto dos Santos Brito, Keise Adrielle Santos Pereira, Keise Adrielle Santos Pereira, William Botelho de Brito, William Botelho de Brito, Maria Karoliny da Silva Torres, Maria Karoliny da Silva Torres, Jeferson da Costa Lopes, Jeferson da Costa Lopes, Erika Ferreira dos Santos, Erika Ferreira dos Santos, Flávia Póvoa da Costa, Flávia Póvoa da Costa, Kevin Matheus Lima de Sarges, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Marcos Henrique Damasceno Cantanhede, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Maria de Nazaré do Socorro de Almeida Viana, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Rosilene da Silva, Giselle Maria Rachid Viana, Tânia do Socorro Souza Chaves, Tânia do Socorro Souza Chaves, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro dos Santos, Juliana Abreu Lima Nunes, Iran Barros Costa, Iran Barros Costa, Ednelza da Silva Graça Amoras, Sandra Souza Lima, Izaura Maria Vieira Cayres-Vallinoto, Izaura Maria Vieira Cayres-Vallinoto, Igor Brasil-Costa, Igor Brasil-Costa, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto

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O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos by Rui Antunes Pereira, Marta Sousa, José Pedro Cidade, Luís Melo, Diogo Lopes, Sara Ventura, Irene Aragão, Raul Miguel de Freitas Lima Neto, Elena Molinos, Ana Marques, Nelson Cardoso, Flávio Marino, Filipa Brás Monteiro, Ana Pinho Oliveira, Rogério C Silva, André Miguel Neto Real, Bruno Sarmento Banheiro, Renato Reis, Maria Adão-Serrano, Ana Cracium, Ana Valadas, João Miguel Ribeiro, Pedro Póvoa, Camila Tapadinhas, Vítor Mendes, Luís Coelho, Raquel Maia, Paulo Telles Freitas, Isabel Amorim Ferreira, Tiago Ramires, Luís Silva Val-Flores, Mariana Cascão, Rita Alves, Simão C Rodeia, Cleide Barrigoto, Rosa Cardiga, Maria João Ferreira da Silva, Bruno Vale, Tatiana Fonseca, Ana Lúcia Rios, João Camões, Danay Pérez, Susana Cabral, Maria Inês Ribeiro, João João Mendes, João Gouveia, Susana Mendes Fernandes

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Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α by Maria Alice Freitas Queiroz, Wandrey Roberto dos Santos Brito, Keise Adrielle Santos Pereira, Leonn Mendes Soares Pereira, Ednelza da Silva Graça Amoras, Sandra Souza Lima, Erika Ferreira dos Santos, Flávia Póvoa da Costa, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Giselle Maria Rachid Viana, Tânia do Socorro Souza Chaves, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Juliana Abreu Lima Nunes, Iran Barros Costa, Izaura Maria Vieira Cayres-Vallinoto, Igor Brasil-Costa, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto

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Capítulo 13 - Hipertensão Arterial Resistente by MVB Malachias, WKSB Souza, FL Plavnik, CIS Rodrigues, AA Brandão, MFT Neves, LA Bortolotto, RJS Franco, CE Poli-de-Figueiredo, PCBV Jardim, C Amodeo, ECD Barbosa, V Koch, MAM Gomes, RB Paula, RMS Póvoa, FC Colombo, S Ferreira Filho, RD Miranda, CA Machado, F Nobre, AR Nogueira, D Mion Júnior, S Kaiser, CLM Forjaz, FA Almeida, JFV Martim, N Sass, LF Drager, E Muxfeldt, LC Bodanese, AD Feitosa, D Malta, S Fuchs, ME Magalhães, W Oigman, O Moreira Filho, AMG Pierin, GS Feitosa, MRFL Bortolotto, LBNC Magalhães, ACS Silva, JM Ribeiro, FAO Borelli, M Gus, O Passarelli Júnior, JY Toledo, GF Salles, LC Martins, TSV Jardim, ICB Guimarães, IC Antonello, E Lima Júnior, V Matsudo, GV Silva, LS Costa, A Alessi, LCN Scala, EB Coelho, D Souza, HF Lopes, MMG Gowdak, AC Cordeiro Júnior, MR Torloni, MRST Klein, PK Nogueira, LAD Lotaif, GBA Rosito, H Moreno Júnior

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