Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial. by Maclaren, R, Groppe, M, Barnard, A, Cottriall, C, Tolmachova, T, Seymour, L, Clark, K, During, M, Cremers, F, Black, G, Lotery, A, Downes, S, Webster, A, Seabra, M

Human mesothelioma cell lines developed from malignant pleural effusions as tools to develop novel therapies and guide personalised medicine by Kanellakis, N, Asciak, R, Yao, X, Peng, Y, Mercer, R, Sherrill, T, Maldonado, F, Ebner, D, Seymour, L, Rintoul, R, Blackwell, T, Stathopoulos, G, Dong, T, Rahman, N, Psallidas, I

An oncolytic virus expressing a T-cell engager simultaneously targets cancer and immunosuppressive stromal cells by Freedman, J, Duffy, M, Lei-Rossmann, J, Muntzer, A, Scott, E, Hagel, J, Campo, L, Bryant, R, Verrill, C, Lambert, A, Miller, P, Champion, B, Seymour, L, Fisher, K

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection. by Garcia-Carbonero, R, Salazar, R, Duran, I, Osman-Garcia, I, Paz-Ares, L, Bozada, J, Boni, V, Blanc, C, Seymour, L, Beadle, J, Alvis, S, Champion, B, Calvo, E, Fisher, K

MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas. by Walls, G, Lemos, M, Javid, M, Bazan-Peregrino, M, Jeyabalan, J, Reed, A, Harding, B, Tyler, D, Stuckey, D, Piret, S, Christie, P, Ansorge, O, Clarke, K, Seymour, L, Thakker, R

Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators by Dyer, A, Di, Y, Calderon, H, Illingworth, S, Kueberuwa, G, Tedcastle, A, Jakeman, P, Chia, S, Brown, A, Silva, M, Barlow, D, Beadle, J, Hermiston, T, Ferguson, D, Champion, B, Fisher, K, Seymour, L

Adenovirus vectors induce expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1 infection by Benlahrech, A, Harris, J, Meiser, A, Papagatsias, T, Hornig, J, Hayes, P, Lieber, A, Athanasopoulos, T, Bachy, V, Daniels, R, Fisher, K, Gotch, F, Klavinskis, L, Seymour, L, Logan, K, Barbagallo, R, Dickson, G, Patterson, S

Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer. by Seymour, L, Ferry, DR, Kerr, D, Rea, D, Whitlock, M, Poyner, R, Boivin, C, Hesslewood, S, Twelves, C, Blackie, R, Schatzlein, A, Jodrell, D, Bissett, D, Calvert, H, Lind, M, Robbins, A, Burtles, S, Duncan, R, Cassidy, J

Retinal gene therapy in patients with choroideremia: Initial fi ndings from a phase 1/2 clinical trial by MacLaren, R, MacLaren, R, MacLaren, R, Groppe, M, Groppe, M, Groppe, M, Barnard, A, Cottriall, C, Tolmachova, T, Seymour, L, Reed Clark, K, During, M, Cremers, F, Black, G, Lotery, A, Downes, S, Downes, S, Webster, A, Webster, A, Seabra, M, Seabra, M

Promises and challenges of adoptive T-cell therapies for solid tumours by Morotti, M, Albukhari, A, Alsaadi, A, Artibani, M, Brenton, JD, Curbishley, SM, Dong, T, Dustin, ML, Hu, Z, McGranahan, N, Miller, ML, Santana-Gonzalez, L, Seymour, L, Shi, T, Van Loo, P, Yau, C, White, H, Wietek, N, Church, DN, Wedge, DC, Ahmed, A

Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic–hydrophilic copolymers by Read, M

Other Authors: “…Seymour, L…”

Exploring the effects of nutrient deprivation and waste accumulation on T cells and oncolytic adenoviruses; in order to create immune activators for tumour therapy by Frost, SC

Other Authors: “…Seymour, L…”

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens by Wong, S

Other Authors: “…Seymour, L…”

Exploring the interface between endoplasmic reticulum stress and oncolytic adenoviruses by Taverner, WK

Other Authors: “…Seymour, L…”

Exploring the relationship between cancer metabolism and oncolytic adenoviruses by Dyer, A

Other Authors: “…Seymour, L…”

Reprogramming the extracellular matrix to create a proinflammatory microenvironment by Caviezel, F

Other Authors: “…Seymour, L…”

Regulation of MITF and Brn2 in melanoma by Agkatsev, S

Other Authors: “…Seymour, L…”

Assessing the mechanistic synergy between cancer virotherapy and external beam radiation by Pokrovska, T

Other Authors: “…Seymour, L…”

Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

Other Authors: “…Seymour, L…”

Targeting polymer coated adenovirus to tumour-associated vasculature by Bachtarzi, H

Other Authors: “…Seymour, L…”