Showing 21 - 28 results of 28 for search 'Siggs, O', query time: 0.05s
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21
A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding. by Iavarone, C, Ramsauer, K, Kubarenko, A, Debasitis, J, Leykin, I, Weber, A, Siggs, O, Beutler, B, Zhang, P, Otten, G, D'Oro, U, Valiante, N, Mbow, M, Visintin, A
Published 2011Journal article -
22
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha. by Siggs, O, Berger, M, Krebs, P, Arnold, C, Eidenschenk, C, Huber, C, Pirie, E, Smart, N, Khovananth, K, Xia, Y, McInerney, G, Karlsson Hedestam, G, Nemazee, D, Beutler, B
Published 2010Journal article -
23
An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. by Berger, M, Krebs, P, Crozat, K, Li, X, Croker, B, Siggs, O, Popkin, D, Du, X, Lawson, B, Theofilopoulos, A, Xia, Y, Khovananth, K, Moresco, E, Satoh, T, Takeuchi, O, Akira, S, Beutler, B
Published 2010Journal article -
24
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations by Bull, K, Rimmer, A, Siggs, O, Miosge, L, Roots, C, Enders, A, Bertram, E, Crockford, T, Whittle, B, Potter, P, Simon, M, Mallon, A, Brown, S, Beutler, B, Goodnow, C, Lunter, G, Cornall, R
Published 2013Journal article -
25
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses. by Zak, D, Schmitz, F, Gold, E, Diercks, A, Peschon, J, Valvo, J, Niemistö, A, Podolsky, I, Fallen, S, Suen, R, Stolyar, T, Johnson, C, Kennedy, K, Hamilton, M, Siggs, O, Beutler, B, Aderem, A
Published 2011Journal article -
26
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events. by Colak, E, Leslie, A, Zausmer, K, Khatamzas, E, Kubarenko, A, Pichulik, T, Klimosch, SN, Mayer, A, Siggs, O, Hector, A, Fischer, R, Klesser, B, Rautanen, A, Frank, M, Hill, A, Manoury, B, Beutler, B, Hartl, D, Simmons, A, Weber, A
Published 2014Journal article -
27
Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity. by Siggs, O, Stockenhuber, A, Deobagkar-Lele, M, Bull, K, Crockford, T, Kingston, B, Crawford, G, Anzilotti, C, Steeples, V, Ghaffari, S, Czibik, G, Bellahcene, M, Watkins, H, Ashrafian, H, Davies, B, Woods, A, Carling, D, Yavari, A, Beutler, B, Cornall, R
Published 2016Journal article -
28
ENU-induced phenovariance in mice: inferences from 587 mutations. by Arnold, C, Barnes, M, Berger, M, Blasius, A, Brandl, K, Croker, B, Crozat, K, Du, X, Eidenschenk, C, Georgel, P, Hoebe, K, Huang, H, Jiang, Z, Krebs, P, La Vine, D, Li, X, Lyon, S, Moresco, E, Murray, A, Popkin, D, Rutschmann, S, Siggs, O, Smart, N, Sun, L, Tabeta, K, Webster, V, Tomisato, W, Won, S, Xia, Y, Xiao, N, Beutler, B
Published 2012Journal article