Effectiveness and Safety of Tecneplase vs. Alteplase in the Acute Treatment of Ischemic Stroke by Ángel Estella, Miriam Pérez Ruiz, Juan José Serrano

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Latest developments in early diagnosis and specific treatment of severe influenza infection by Francisco Valenzuela-Sánchez, Blanca Valenzuela-Méndez, Juan Francisco Rodríguez-Gutiérrez, Ángel Estella

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Managing the Next Wave of Influenza and/or SARS-CoV-2 in the ICU—Practical Recommendations from an Expert Group for CAPA/IAPA Patients by Jose Peral, Ángel Estella, Xavier Nuvials, Alejandro Rodríguez, Iratxe Seijas, Cruz Soriano, Borja Suberviola, Rafael Zaragoza

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Microbiological diagnosis of pulmonary invasive aspergillosis in critically ill patients with severe SARS-CoV-2 pneumonia: a bronchoalveolar study by Ángel Estella, Ignacio Martín-Loeches, María Recuerda Núñez, Clara González García, Liliana Marcela Pesaresi, Alvaro Antón Escors, Maria Dolores López Prieto, Juan Manuel Sánchez Calvo

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Plasma Levels of Mid-Regional Proadrenomedullin Accurately Identify H1N1pdm09 Influenza Virus Patients with Risk of Intensive Care Admission and Mortality in the Emergency Departme... by Blanca Valenzuela-Méndez, Francisco Valenzuela-Sánchez, Juan Francisco Rodríguez-Gutiérrez, Rafael Bohollo-de-Austria, Ángel Estella, Pilar Martínez-García, María Ángela González-García, Jordi Rello

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Correction: Microbiological diagnosis of pulmonary invasive aspergillosis in critically ill patients with severe SARS-CoV-2 pneumonia: a bronchoalveolar study by Ángel Estella, Ignacio Martín-Loeches, María Recuerda Núñez, Clara González García, Liliana Marcela Pesaresi, Alvaro Antón Escors, Maria Dolores López Prieto, Juan Manuel Sánchez Calvo

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Anticipatory Antifungal Treatment in Critically Ill Patients with SARS-CoV-2 Pneumonia by Ángel Estella, María Recuerda Núñez, Carolina Lagares, Manuel Gracia Romero, Eva Torres, Juan Carlos Alados Arboledas, Álvaro Antón Escors, Clara González García, Dolores Sandar Núñez, Dolores López Prieto, Juan Manuel Sánchez Calvo

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Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts by Yasser Sakr, Bruno François, Jordi Solé-Violan, Katarzyna Kotfis, Ulrich Jaschinski, Angel Estella, Marc Leone, Stephan M. Jakob, Xavier Wittebole, Luis E. Fontes, Miguel de Melo Gurgel, Thais Midega, Jean-Louis Vincent, V. Marco Ranieri, the SOAP and ICON Investigators

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Prognostic Value of Procalcitonin and C-Reactive Protein in 1608 Critically Ill Patients with Severe Influenza Pneumonia by Raquel Carbonell, Gerard Moreno, Ignacio Martín-Loeches, Frederic Gomez-Bertomeu, Carolina Sarvisé, Josep Gómez, María Bodí, Emili Díaz, Elisabeth Papiol, Sandra Trefler, Mercedes Nieto, Angel Estella, María Jiménez Herrera, Pablo Vidal Cortés, Juan José Guardiola, Jordi Solé-Violán, Alejandro Rodríguez

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Vaccinated Patients Admitted in ICU with Severe Pneumonia Due to SARS-CoV-2: A Multicenter Pilot Study by Ángel Estella, Mª Luisa Cantón, Laura Muñoz, Isabel Rodriguez Higueras, María Recuerda Núñez, Julia Tejero Aranguren, Benito Zaya, Carmen Gómez, Rosario Amaya, Ángela Hurtado Martinez, María del Valle Odero Bernal, Carmen De la Fuente, Juan Carlos Alados, Jose Garnacho-Montero, on behalf of the Group of Infectious Diseases of the Andalusian Society of Intensive Care and Coronary Units SAMIUC

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Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review by Francisco Javier Candel, Miguel Salavert, Angel Estella, Miquel Ferrer, Ricard Ferrer, Julio Javier Gamazo, Carolina García-Vidal, Juan González del Castillo, Víctor José González-Ramallo, Federico Gordo, Manuel Mirón-Rubio, Javier Pérez-Pallarés, Cristina Pitart, José Luís del Pozo, Paula Ramírez, Pedro Rascado, Soledad Reyes, Patricia Ruiz-Garbajosa, Borja Suberviola, Pablo Vidal, Rafael Zaragoza

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Ten Issues for Updating in Community-Acquired Pneumonia: An Expert Review by Francisco Javier Candel, Miguel Salavert, Miren Basaras, Marcio Borges, Rafael Cantón, Emilia Cercenado, Catian Cilloniz, Ángel Estella, Juan M. García-Lechuz, José Garnacho Montero, Federico Gordo, Agustín Julián-Jiménez, Francisco Javier Martín-Sánchez, Emilio Maseda, Mayra Matesanz, Rosario Menéndez, Manuel Mirón-Rubio, Raúl Ortiz de Lejarazu, Eva Polverino, Pilar Retamar-Gentil, Luis Alberto Ruiz-Iturriaga, Susana Sancho, Leyre Serrano

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Mortality comparison between the first and second/third waves among 3,795 critical COVID-19 patients with pneumonia admitted to the ICU: A multicentre retrospective cohort study by Raquel Carbonell, Silvia Urgelés, Alejandro Rodríguez, María Bodí, Ignacio Martín-Loeches, Jordi Solé-Violán, Emili Díaz, Josep Gómez, Sandra Trefler, Montserrat Vallverdú, Josefa Murcia, Antonio Albaya, Ana Loza, Lorenzo Socias, Juan Carlos Ballesteros, Elisabeth Papiol, Lucía Viña, Susana Sancho, Mercedes Nieto, Maria del Carmen Lorente, Oihane Badallo, Virginia Fraile, Fernando Arméstar, Angel Estella, Laura Sanchez, Isabel Sancho, Antonio Margarit, Gerard Moreno

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Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain by Alejandro Rodríguez, Manuel Ruiz-Botella, Ignacio Martín-Loeches, María Jimenez Herrera, Jordi Solé-Violan, Josep Gómez, María Bodí, Sandra Trefler, Elisabeth Papiol, Emili Díaz, Borja Suberviola, Montserrat Vallverdu, Eric Mayor-Vázquez, Antonio Albaya Moreno, Alfonso Canabal Berlanga, Miguel Sánchez, María del Valle Ortíz, Juan Carlos Ballesteros, Lorena Martín Iglesias, Judith Marín-Corral, Esther López Ramos, Virginia Hidalgo Valverde, Loreto Vidaur Vidaur Tello, Susana Sancho Chinesta, Francisco Javier Gonzáles de Molina, Sandra Herrero García, Carmen Carolina Sena Pérez, Juan Carlos Pozo Laderas, Raquel Rodríguez García, Angel Estella, Ricard Ferrer, on behalf of COVID-19 SEMICYUC Working Group

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Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational... by Luis Felipe Reyes, Alejandro Rodriguez, Yuli V. Fuentes, Sara Duque, Esteban García-Gallo, Alirio Bastidas, Cristian C. Serrano-Mayorga, Elsa D. Ibáñez-Prada, Gerard Moreno, Paula C. Ramirez-Valbuena, Gustavo Ospina-Tascon, Glenn Hernandez, Edwin Silva, Ana Maria Díaz, Manuel Jibaja, Magdalena Vera-Alarcon, Emili Díaz, María Bodí, Jordi Solé-Violán, Ricard Ferrer, Antonio Albaya-Moreno, Lorenzo Socias, William Figueroa, Jose L. Lozano-Villanueva, Fabio Varón-Vega, Ángel Estella, Ana Loza-Vazquez, Ruth Jorge-García, Isabel Sancho, Manu Shankar-Hari, Ignacio Martin-Loeches, LIVEN-Covid-19, SEMICYUC Study Group

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A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study by David de Gonzalo-Calvo, Marta Molinero, Iván D. Benítez, Manel Perez-Pons, Nadia García-Mateo, Alicia Ortega, Tamara Postigo, María C. García-Hidalgo, Thalia Belmonte, Carlos Rodríguez-Muñoz, Jessica González, Gerard Torres, Clara Gort-Paniello, Anna Moncusí-Moix, Ángel Estella, Luis Tamayo Lomas, Amalia Martínez de la Gándara, Lorenzo Socias, Yhivian Peñasco, Maria Del Carmen de la Torre, Elena Bustamante-Munguira, Elena Gallego Curto, Ignacio Martínez Varela, María Cruz Martin Delgado, Pablo Vidal-Cortés, Juan López Messa, Felipe Pérez-García, Jesús Caballero, José M. Añón, Ana Loza-Vázquez, Nieves Carbonell, Judith Marin-Corral, Ruth Noemí Jorge García, Carmen Barberà, Adrián Ceccato, Laia Fernández-Barat, Ricard Ferrer, Dario Garcia-Gasulla, Jose Ángel Lorente-Balanza, Rosario Menéndez, Ana Motos, Oscar Peñuelas, Jordi Riera, Jesús F. Bermejo-Martin, Antoni Torres, Ferran Barbé

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The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients by Antoni Torres, Anna Motos, Jordi Riera, Laia Fernández-Barat, Adrián Ceccato, Raquel Pérez-Arnal, Dario García-Gasulla, Oscar Peñuelas, José Angel Lorente, Alejandro Rodriguez, David de Gonzalo-Calvo, Raquel Almansa, Albert Gabarrús, Rosario Menéndez, Jesús F. Bermejo-Martin, Ricard Ferrer, Rosario Amaya Villar, José M. Añón, Carme Barberà, José Barberán, Aaron Blandino Ortiz, Elena Bustamante-Munguira, Jesús Caballero, Cristina Carbajales, Nieves Carbonell, Mercedes Catalán-González, Cristóbal Galbán, Víctor D. Gumucio-Sanguino, Maria del Carmen de la Torre, Emili Díaz, Ángel Estella, Elena Gallego, José Luis García Garmendia, José Garnacho-Montero, José M. Gómez, Arturo Huerta, Ruth Noemí Jorge García, Ana Loza-Vázquez, Judith Marin-Corral, Amalia Martínez de la Gándara, Ignacio Martínez Varela, Juan López Messa, Guillermo M. Albaiceta, Mariana Andrea Novo, Yhivian Peñasco, Juan Carlos Pozo-Laderas, Pilar Ricart, Inmaculada Salvador-Adell, Angel Sánchez-Miralles, Susana Sancho Chinesta, Lorenzo Socias, Jordi Solé-Violan, Fernando Suares Sipmann, Luis Tamayo Lomas, José Trenado, Ferran Barbé, CIBERESUCICOVID Project (COV20/00110, ISCIII)

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Prognostic implications of comorbidity patterns in critically ill COVID-19 patients: A multicenter, observational study by Iván D. Benítez, Jordi de Batlle, Gerard Torres, Jessica González, David de Gonzalo-Calvo, Adriano D.S. Targa, Clara Gort-Paniello, Anna Moncusí-Moix, Adrián Ceccato, Laia Fernández-Barat, Ricard Ferrer, Dario Garcia-Gasulla, Rosario Menéndez, Anna Motos, Oscar Peñuelas, Jordi Riera, Jesús F. Bermejo-Martin, Yhivian Peñasco, Pilar Ricart, María Cruz Martin Delgado, Luciano Aguilera, Alejandro Rodríguez, Maria Victoria Boado Varela, Fernando Suarez-Sipmann, Juan Carlos Pozo-Laderas, Jordi Solé-Violan, Maite Nieto, Mariana Andrea Novo, José Barberán, Rosario Amaya Villar, José Garnacho-Montero, Jose Luis García-Garmendia, José M. Gómez, José Ángel Lorente, Aaron Blandino Ortiz, Luis Tamayo Lomas, Esther López-Ramos, Alejandro Úbeda, Mercedes Catalán-González, Angel Sánchez-Miralles, Ignacio Martínez Varela, Ruth Noemí Jorge García, Nieves Franco, Víctor D. Gumucio-Sanguino, Arturo Huerta Garcia, Elena Bustamante-Munguira, Luis Jorge Valdivia, Jesús Caballero, Elena Gallego, Amalia Martínez de la Gándara, Álvaro Castellanos-Ortega, Josep Trenado, Judith Marin-Corral, Guillermo M Albaiceta, Maria del Carmen de la Torre, Ana Loza-Vázquez, Pablo Vidal, Juan Lopez Messa, Jose M. Añón, Cristina Carbajales Pérez, Victor Sagredo, Neus Bofill, Nieves Carbonell, Lorenzo Socias, Carme Barberà, Angel Estella, Manuel Valledor Mendez, Emili Diaz, Ana López Lago, Antoni Torres, Ferran Barbé

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