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  1. 1
    A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3

    A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3 per Ana C. Valencia-Olvera, Deebika Balu, Shreya Bellur, Thomas McNally, Yaseen Saleh, Don Pham, Shivesh Ghura, Jason York, Jan O. Johansson, Mary Jo LaDu, Leon Tai

    Publicat 2023-12-01
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  2. 2
    Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment

    Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment per Dean Gilham, Sylwia Wasiak, Brooke D. Rakai, Li Fu, Laura M. Tsujikawa, Christopher D. Sarsons, Agostina Carestia, Kenneth Lebioda, Jan O. Johansson, Michael Sweeney, Kamyar Kalantar-Zadeh, Ewelina Kulikowski

    Publicat 2023-06-01
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  3. 3
    Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease

    Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease per Sylwia Wasiak, Dean Gilham, Emily Daze, Laura M. Tsujikawa, Christopher Halliday, Stephanie C. Stotz, Brooke D. Rakai, Li Fu, Ravi Jahagirdar, Michael Sweeney, Jan O. Johansson, Norman C. W. Wong, Ewelina Kulikowski

    Publicat 2020-01-01
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  4. 4
    Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-Cov-2 Infection In Vitro

    Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-Cov-2 Infection In Vitro per Dean Gilham, Audrey L. Smith, Li Fu, Dalia Y. Moore, Abenaya Muralidharan, St. Patrick M. Reid, Stephanie C. Stotz, Jan O. Johansson, Michael Sweeney, Norman C. W. Wong, Ewelina Kulikowski, Dalia El-Gamal

    Publicat 2021-04-01
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