Thin Air, Thick Vessels: Historical and Current Perspectives on Hypoxic Pulmonary Hypertension gan Jason M. Young, Jason M. Young, David R. Williams, A. A. Roger Thompson, A. A. Roger Thompson

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Soluble P-Selectin and von Willebrand Factor Rise in Healthy Volunteers Following Non-exertional Ascent to High Altitude gan Helena A. Turton, Josephine Pickworth, Gordon G. Paterson, Gordon G. Paterson, Allan Lawrie, J. Kenneth Baillie, J. Kenneth Baillie, A. A. Roger Thompson, A. A. Roger Thompson, A. A. Roger Thompson

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When Innate Immunity Meets Angiogenesis—The Role of Toll-Like Receptors in Endothelial Cells and Pulmonary Hypertension gan Aneel Bhagwani, Aneel Bhagwani, A. A. Roger Thompson, Laszlo Farkas

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Pulmonary hypertension phenotypes in patients with systemic sclerosis gan Ashraful Haque, David G. Kiely, Gabor Kovacs, A.A. Roger Thompson, Robin Condliffe

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Editorial: Pulmonary Hypertension: Mechanisms and Management, History and Future gan A. A. Roger Thompson, A. A. Roger Thompson, Martin R. Wilkins, Jim M. Wild, Jim M. Wild, Jim M. Wild, David G. Kiely, David G. Kiely, David G. Kiely, Allan Lawrie, Allan Lawrie

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The Role of Neutrophils and Neutrophil Elastase in Pulmonary Arterial Hypertension gan Shalina Taylor, Shalina Taylor, Omar Dirir, Roham T. Zamanian, Roham T. Zamanian, Marlene Rabinovitch, Marlene Rabinovitch, A. A. Roger Thompson

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Mendelian Randomization Study With Clinical Follow‐Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension gan Elham Alhathli, Thomas Julian, Zain Ul Abideen Girach, A. A. Roger Thompson, Christopher Rhodes, Stefan Gräf, Niamh Errington, Martin R. Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper‐Knock

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Non-invasive detection of severe PH in lung disease using magnetic resonance imaging gan Dheyaa Alkhanfar, Dheyaa Alkhanfar, Dheyaa Alkhanfar, Krit Dwivedi, Faisal Alandejani, Yousef Shahin, Yousef Shahin, Samer Alabed, Samer Alabed, Chris Johns, Pankaj Garg, A. A. Roger Thompson, A. A. Roger Thompson, Alexander M. K. Rothman, Alexander M. K. Rothman, Abdul Hameed, Athanasios Charalampopoulos, Jim M. Wild, Jim M. Wild, Robin Condliffe, David G. Kiely, David G. Kiely, Andrew J. Swift, Andrew J. Swift

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Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry gan Kris Bauchmuller, Robin Condliffe, Jennifer Southern, Catherine Billings, Athanasios Charalampopoulos, Charlie A. Elliot, Abdul Hameed, David G. Kiely, Ian Sabroe, A.A. Roger Thompson, Ajay Raithatha, Gary H. Mills

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Selective improvement of pulmonary arterial hypertension with a dual ET/ET receptors antagonist in the apolipoprotein E model of PAH and atherosclerosis gan Lewis Renshall, Nadine Arnold, Laura West, Adam Braithwaite, Josephine Pickworth, Rachel Walker, Mabruka Alfaidi, Janet Chamberlain, Helen Casbolt, A.A. Roger Thompson, Cathy Holt, Marc Iglarz, Sheila Francis, Allan Lawrie

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A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study gan Amy Gilmour, Chloe Hughes, Yan Hui Giam, Rebecca C. Hull, Thomas Pembridge, Hani Abo-Leyah, A.A. Roger Thompson, Alison M. Condliffe, Amelia Shoemark, James D. Chalmers, Merete B. Long

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Elective lower limb orthopedic arthroplasty surgery in patients with pulmonary hypertension gan Mikaela Wardle, Amanda Nair, Sarah Saunders, Iain Armstrong, Athanasios Charalampopoulos, Charlie Elliot, Abdul Hameed, Neil Hamilton, John Harrington, Carol Keen, Robert Lewis, Ian Sabroe, A. A. Roger Thompson, Robert M. Kerry, Robin Condliffe, David G. Kiely

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Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the protein kinase C inhibitor ruboxistaurin gan Rebecca Dowey, Joby Cole, A.A. Roger Thompson, Rebecca C. Hull, Chenghao Huang, Jacob Whatmore, Ahmed Iqbal, Kirsty L. Bradley, Joanne McKenzie, Allan Lawrie, Alison M. Condliffe, Endre Kiss-Toth, Ian Sabroe, Lynne R. Prince

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Incremental Shuttle Walking Test Distance Is Reduced in Patients With Pulmonary Hypertension in World Health Organisation Functional Class I gan Catherine G. Billings, Robert Lewis, Iain J. Armstrong, Judith A. Hurdman, Ian A. Smith, Matthew Austin, Charlie A. Elliot, Athanasios Charalampopoulos, Ian Sabroe, Allan Lawrie, A. A. Roger Thompson, Robin Condliffe, David G. Kiely, David G. Kiely, David G. Kiely

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Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative computed tomography gan Dheyaa Alkhanfar, Yousef Shahin, Faisal Alandejani, Krit Dwivedi, Samer Alabed, Chris Johns, Allan Lawrie, A.A. Roger Thompson, Alexander M.K. Rothman, Juerg Tschirren, Johanna M. Uthoff, Eric Hoffman, Robin Condliffe, Jim M. Wild, David G. Kiely, Andrew J. Swift

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Network analysis reveals distinct clinical syndromes underlying acute mountain sickness. gan David P Hall, Ian J C MacCormick, Alex T Phythian-Adams, Nina M Rzechorzek, David Hope-Jones, Sorrel Cosens, Stewart Jackson, Matthew G D Bates, David J Collier, David A Hume, Thomas Freeman, A A Roger Thompson, John Kenneth Baillie

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A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach gan Niamh Errington, James Iremonger, Josephine A. Pickworth, Sokratis Kariotis, Christopher J. Rhodes, Alexander MK Rothman, Robin Condliffe, Charles A. Elliot, David G. Kiely, Luke S. Howard, John Wharton, A. A. Roger Thompson, Nicholas W Morrell, Martin R. Wilkins, Dennis Wang, Allan Lawrie

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Unsupervised machine learning to investigate trajectory patterns of COVID-19 symptoms and physical activity measured via the MyHeart Counts App and smart devices gan Varsha Gupta, Sokratis Kariotis, Mohammed D. Rajab, Niamh Errington, Elham Alhathli, Emmanuel Jammeh, Martin Brook, Naomi Meardon, Paul Collini, Joby Cole, Jim M. Wild, Steven Hershman, Ali Javed, A. A. Roger Thompson, Thushan de Silva, Euan A. Ashley, Dennis Wang, Allan Lawrie

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Imaging and Risk Stratification in Pulmonary Arterial Hypertension: Time to Include Right Ventricular Assessment gan Faisal Alandejani, Abdul Hameed, Abdul Hameed, Euan Tubman, Samer Alabed, Samer Alabed, Yousef Shahin, Yousef Shahin, Robert A. Lewis, Robert A. Lewis, Krit Dwivedi, Aqeeb Mahmood, Jennifer Middleton, Jennifer Middleton, Lisa Watson, Dheyaa Alkhanfar, Christopher S. Johns, Smitha Rajaram, Pankaj Garg, Robin Condliffe, Charlie A. Elliot, A. A. Roger Thompson, A. A. Roger Thompson, Alexander M. K. Rothman, Alexander M. K. Rothman, Alexander M. K. Rothman, Athanasios Charalampopoulos, Allan Lawrie, Jim M. Wild, Jim M. Wild, Andrew J. Swift, Andrew J. Swift, David G. Kiely, David G. Kiely, David G. Kiely

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A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3 gan Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Stephen Y. Chan, Delphine Gomez, Elena A. Goncharova, Laszlo Farkas

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