Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures by Tatsuya Ikenoue, Francesco A. Aprile, Francesco A. Aprile, Pietro Sormanni, Michele Vendruscolo

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Natural Inhibitors of Amyloid Aggregation by Paolo Tortora, Francesco A. Aprile

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A Facile Method to Produce N-Terminally Truncated α-Synuclein by Rebecca J. Thrush, Rebecca J. Thrush, Devkee M. Vadukul, Francesco A. Aprile, Francesco A. Aprile

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Structure of a low-population intermediate state in the release of an enzyme product by Alfonso De Simone, Francesco A Aprile, Anne Dhulesia, Christopher M Dobson, Michele Vendruscolo

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P1563: INTRACELLULAR IRON OVERLOAD IMPAIRS HSC FUNCTION BY AFFECTING MITOCHONDRIAL FITNESS IN ΒETA-THALASSEMIA by S. Sighinolfi, A. Aprile, L. Cassina, M. Panzeri, S. Beretta, M. Storto, A. Boletta, I. Merelli, G. Ferrari

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A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF by Alessandra Bigi, Liliana Napolitano, Devkee M. Vadukul, Fabrizio Chiti, Cristina Cecchi, Francesco A. Aprile, Roberta Cascella

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The relationship between aggregation and toxicity of polyglutamine-containing ataxin-3 in the intracellular environment of Escherichia coli. by Gaetano Invernizzi, Francesco A Aprile, Antonino Natalello, Andrea Ghisleni, Amanda Penco, Annalisa Relini, Silvia M Doglia, Paolo Tortora, Maria E Regonesi

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P1519: EXPLORING THE ROLE OF FGF23 IN BETA-THALASSEMIA: A NOVEL THERAPEUTIC TARGET TO AMELIORATE ALTERED INTERACTIONS BETWEEN HSC AND BONE MARROW NICHE by L. Raggi, A. Aprile, S. Bolamperti, I. Villa, M. Storto, G. Morello, S. Marktel, C. Tripodo, M. D. Cappellini, I. Motta, A. Rubinacci, G. Ferrari

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P1397: CHRONICALLY REDUCED LEVELS OF THROMBOPOIETIN IMPAIR HEMATOPOIETIC STEM CELL FUNCTION AND MEGAKARYOCYTE BONE MARROW NICHE by A. Aprile, M. Storto, A. Malara, A. Gulino, L. Raggi, S. Sighinolfi, S. Beretta, I. Merelli, S. Marktel, M. Ponzoni, C. Tripodo, A. Balduini, G. Ferrari

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Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain. by Francesco A Aprile, Anne Dhulesia, Florian Stengel, Cintia Roodveldt, Justin L P Benesch, Paolo Tortora, Carol V Robinson, Xavier Salvatella, Christopher M Dobson, Nunilo Cremades

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Rationally Designed Antibodies as Research Tools to Study the Structure–Toxicity Relationship of Amyloid-β Oligomers by Ryan Limbocker, Benedetta Mannini, Rodrigo Cataldi, Shianne Chhangur, Aidan K. Wright, Ryan P. Kreiser, J. Alex Albright, Sean Chia, Johnny Habchi, Pietro Sormanni, Janet R. Kumita, Francesco S. Ruggeri, Christopher M. Dobson, Fabrizio Chiti, Francesco A. Aprile, Michele Vendruscolo

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Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression by Suman De, Daniel R. Whiten, Francesco S. Ruggeri, Craig Hughes, Margarida Rodrigues, Dimitrios I. Sideris, Christopher G. Taylor, Francesco A. Aprile, Serge Muyldermans, Tuomas P. J. Knowles, Michele Vendruscolo, Clare Bryant, Kaj Blennow, Ingmar Skoog, Silke Kern, Henrik Zetterberg, David Klenerman

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The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes by Federica Raguseo, Yiran Wang, Jessica Li, Marija Petrić Howe, Rubika Balendra, Anouk Huyghebaert, Devkee M. Vadukul, Diana A. Tanase, Thomas E. Maher, Layla Malouf, Roger Rubio-Sánchez, Francesco A. Aprile, Yuval Elani, Rickie Patani, Lorenzo Di Michele, Marco Di Antonio

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