Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study by F. Lauzier, N. K. Adhikari, A. Seely, K. K. Y. Koo, E. P. Belley-Côté, K. E. A. Burns, D. J. Cook, F. D’Aragon, B. Rochwerg, M. E. Kho, S. J. W. Oczkowksi, E. H. Duan, M. O. Meade, A. G. Day, F. Lamontagne, for ACCADEMY (Academy of Critical Care – Development, Evaluation, and Methodology)

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