Enhancement of Skin Permeability Prediction through PBPK Modeling, Bayesian Inference, and Experiment Design by Abdullah Hamadeh, Abdulkarim Najjar, John Troutman, Andrea Edginton

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Global sensitivity analysis of Open Systems Pharmacology Suite physiologically based pharmacokinetic models by Abdulkarim Najjar, Abdullah Hamadeh, Sophia Krause, Andreas Schepky, Andrea Edginton

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Editorial: Advances in and applications of predictive toxicology: 2022 by Abdulkarim Najjar, Nynke Kramer, Iain Gardner, Thomas Hartung, Thomas Hartung, Thomas Steger-Hartmann

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Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R by Cornelius Hempel, Frank Totzke, Christoph Schächtele, Abdulkarim Najjar, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

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Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance by Tim Fischer, Abdulkarim Najjar, Frank Totzke, Christoph Schächtele, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

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Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion by Abdulkarim Najjar, Jochen Kühnl, Daniela Lange, Camille Géniès, Carine Jacques, Eric Fabian, Anne Zifle, Nicola J. Hewitt, Andreas Schepky

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Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro–in vivo extrapolation... by Engi Abdelhady Algharably, Emma Di Consiglio, Emanuela Testai, Francesca Pistollato, Anna Bal-Price, Abdulkarim Najjar, Reinhold Kreutz, Ursula Gundert-Remy

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Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure by Johanna Ebmeyer, Abdulkarim Najjar, Daniela Lange, Mareike Boettcher, Silja Voß, Katrin Brandmair, Jaqueline Meinhardt, Jochen Kuehnl, Nicola J. Hewitt, Christopher-Tilman Krueger, Andreas Schepky

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Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application by Abdulkarim Najjar, Andreas Schepky, Christopher-Tilman Krueger, Matthew Dent, Sophie Cable, Hequn Li, Sebastien Grégoire, Laurene Roussel, Audrey Noel-Voisin, Nicola J. Hewitt, Estefania Cardamone

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Increasing Accessibility of Bayesian Network-Based Defined Approaches for Skin Sensitisation Potency Assessment by Tomaz Mohoric, Anke Wilm, Stefan Onken, Andrii Milovich, Artem Logavoch, Pascal Ankli, Ghada Tagorti, Johannes Kirchmair, Andreas Schepky, Jochen Kühnl, Abdulkarim Najjar, Barry Hardy, Johanna Ebmeyer

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Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under c... by Thi-Phuong Tao, Ilka Maschmeyer, Edward L. LeCluyse, Eda Rogers, Katrin Brandmair, Silke Gerlach, Julia Przibilla, Fredy Kern, Camille Genies, Carine Jacques, Abdulkarim Najjar, Andreas Schepky, Uwe Marx, Jochen Kühnl, Nicola J. Hewitt

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