c-MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification by Abraham, Brian J., Young, Richard A.

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Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry by Abraham, Brian J., Young, Richard A.

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ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry by Durbin, Adam D., Abraham, Brian J., Lawton, Lee N., Young, Richard A., Sanda, Takaomi

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Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions by Ji, Xiong, Abraham, Brian J., Lee, Tong Ihn, Jaenisch, Rudolf, Bradner, James E., Young, Richard A., Dadon, Daniel Benjamin

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Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers by Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Weintraub, Abraham Selby, Young, Richard A.

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Models of human core transcriptional regulatory circuitries by Saint-André, Violaine, Federation, Alexander J., Lin, Charles Y., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Reddy, Jessica, Young, Richard A.

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Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements by Dowen, Jill M., Bilodeau, Steve, Orlando, David A., Hübner, Michael R., Abraham, Brian J., Spector, David L., Young, Richard A., Young, Richard A.

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Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression by Soldner, Frank, Stelzer, Yonatan, Abraham, Brian J., Latourelle, Jeanne C., Barrasa, M. Inmaculada, Goldmann, Johanna, Myers, Richard H., Jaenisch, Rudolf, Shivalila, Chikdu Shakti, Young, Richard A.

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Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes by Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Zhang, Lyndon Nuoxi, Young, Richard A.

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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes by Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A., Young, Richard A.

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Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors by Kalan, Sampada, Amat, Ramon, Schachter, Miriam Merzel, Kwiatkowski, Nicholas, Abraham, Brian J., Liang, Yanke, Zhang, Tinghu, Olson, Calla M., Larochelle, Stéphane, Gray, Nathanael S., Fisher, Robert P., Young, Richard A.

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The long noncoding RNA Wisper controls cardiac fibrosis and remodeling by Micheletti, Rudi, Plaisance, Isabelle, Abraham, Brian J., Sarre, Alexandre, Ting, Ching-Chia, Alexanian, Michael, Maric, Daniel, Maison, Damien, Nemir, Mohamed, Schroen, Blanche, González, Arantxa, Ounzain, Samir, Pedrazzini, Thierry, Young, Richard A.

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Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma by Zimmerman, Mark W, Durbin, Adam D, He, Shuning, Oppel, Felix, Shi, Hui, Tao, Ting, Li, Zhaodong, Berezovskaya, Alla, Liu, Yu, Zhang, Jinghui, Young, Richard A, Abraham, Brian J, Look, A Thomas

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High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma by Eliades, Philip, Abraham, Brian J., Ji, Zhenyu, Christensen, Camilla L., Kwiatkowski, Nicholas, Kumar, Raj, Njauw, Ching Ni, Taylor, Michael, Miao, Benchun, Zhang, Tinghu, Wong, Kwok-Kin, Gray, Nathanael S., Tsao, Hensin, Young, Richard A., Miller, David M., III

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LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J, Durbin, Adam D, Zimmerman, Mark W, Powers, John T, Missios, Pavlos, Ross, Kenneth N, Perez-Atayde, Antonio R, Bulyk, Martha L, Young, Richard A, Daley, George Q, Look, A Thomas

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LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J., Durbin, Adam D., Zimmerman, Mark W., Powers, John T., Missios, Pavlos, Ross, Kenneth N., Perez-Atayde, Antonio R., Bulyk, Martha L., Young, Richard A., Daley, George Q., Look, A. Thomas

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CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer by Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Gray, Nathanael S., Zhao, Jean J., Young, Richard A.

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EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma by Iniguez, Amanda Balboni, Stolte, Björn, Wang, Emily Jue, Conway, Amy Saur, Alexe, Gabriela, Dharia, Neekesh V., Kwiatkowski, Nicholas, Zhang, Tinghu, Abraham, Brian J., Mora, Jaume, Kalev, Peter, Leggett, Alan, Chowdhury, Dipanjan, Benes, Cyril H., Gray, Nathanael S., Stegmaier, Kimberly, Young, Richard A.

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YY1 Is a Structural Regulator of Enhancer-Promoter Loops by Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Bradner, James E., Gray, Nathanael S., Weintraub, Abraham Selby, Li, Charles Han, Zamudio Montes de Oca, Alicia, Jaenisch, Rudolf, Young, Richard A.

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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer by Betancur, Paola A., Abraham, Brian J., Yiu, Ying Y., Willingham, Stephen B., Khameneh, Farnaz, Zarnegar, Mark, Kuo, Angera H., McKenna, Kelly, Kojima, Yoko, Leeper, Nicholas J., Ho, Po, Gip, Phung, Swigut, Tomek, Sherwood, Richard I., Clarke, Michael F., Somlo, George, Weissman, Irving L., Young, Richard A.

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