DUBbing cancer: Deubiquitylating enzymes involved in epigenetics, DNA damage and the cell cycle as therapeutic targets by Benedikt M Kessler, Adán Pinto Fernández

Get full text

Ubiquitomics: An Overview and Future by George Vere, Rachel Kealy, Benedikt M. Kessler, Adan Pinto-Fernandez

Get full text

Targeted Mass Spectrometry Reveals Interferon-Dependent Eicosanoid and Fatty Acid Alterations in Chronic Myeloid Leukaemia by Hannah C. Scott, Simeon D. Draganov, Zhanru Yu, Benedikt M. Kessler, Adán Pinto-Fernández

Get full text

ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context by Hannah B. L. Jones, Raphael Heilig, Roman Fischer, Benedikt M. Kessler, Adán Pinto-Fernández

Get full text

ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods by Hannah B. L. Jones, Raphael Heilig, Simon Davis, Roman Fischer, Benedikt M. Kessler, Adán Pinto-Fernández

Get full text

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19 by George Vere, Md Rashadul Alam, Sam Farrar, Rachel Kealy, Benedikt M. Kessler, Darragh P. O’Brien, Adán Pinto-Fernández

Get full text

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting by Cyriel S. Olie, Muhammad Riaz, Rebecca Konietzny, Philip D. Charles, Adan Pinto-Fernandez, Szymon M. Kiełbasa, A. Aartsma-Rus, Jelle J. Goeman, Benedikt M. Kessler, Vered Raz

Get full text

USP18 is an essential regulator of muscle cell differentiation and maturation by Cyriel Sebastiaan Olie, Adán Pinto-Fernández, Andreas Damianou, Iolanda Vendrell, Hailiang Mei, Bianca den Hamer, Erik van der Wal, Jessica C. de Greef, Vered Raz, Benedikt M. Kessler

Get full text

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics by Adán Pinto-Fernández, Adán Pinto-Fernández, Simon Davis, Simon Davis, Abigail B. Schofield, Abigail B. Schofield, Hannah C. Scott, Hannah C. Scott, Ping Zhang, Ping Zhang, Eidarus Salah, Eidarus Salah, Eidarus Salah, Sebastian Mathea, Sebastian Mathea, Philip D. Charles, Philip D. Charles, Andreas Damianou, Andreas Damianou, Gareth Bond, Gareth Bond, Roman Fischer, Roman Fischer, Benedikt M. Kessler, Benedikt M. Kessler

Get full text

Regulation of the endosomal SNX27-retromer by OTULIN by Aurelia Stangl, Paul R. Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T. Pfluger, Farid El Oualid, Benedikt M. Kessler, David Komander, Daniel Krappmann

Get full text

1079 Type I interferon regulation by USP18 is a key vulnerability in cancer by Feng Wang, Bing Yang, Benedikt M Kessler, Veronica Jove, Heather Wheeler, Chiachin Wilson Lee, David R Healy, Kymberly Levine, Erik C Ralph, Anand Giddabasappa, Paula Loria, Masaya Yamaguchi, Agustin Casimiro-Garcia, Adan Pinto-Fernandez, Veronique Frattini, Paul Wes

Type I interferon regulation by USP18 is a key vulnerability in cancer by Veronica Jové, Heather Wheeler, Chiachin Wilson Lee, David R. Healy, Kymberly Levine, Erik C. Ralph, Masaya Yamaguchi, Ziyue Karen Jiang, Edward Cabral, Yingrong Xu, Jeffrey Stock, Bing Yang, Anand Giddabasappa, Paula Loria, Agustin Casimiro-Garcia, Benedikt M. Kessler, Adán Pinto-Fernández, Véronique Frattini, Paul D. Wes, Feng Wang

Get full text

USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma by E Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, Linxiang Lan, Thomas M Charlton, Hannah C Scott, Andreas Damianou, George Vere, Eva M Riising, Clive Da Costa, Wojciech W Krajewski, David Guerin, Jeffrey D Kearns, Stephanos Ioannidis, Marie Katz, Crystal McKinnon, Jonathan O'Connell, Natalia Moncaut, Ian Rosewell, Emma Nye, Neil Jones, Claire Heride, Malte Gersch, Min Wu, Christopher J Dinsmore, Tim R Hammonds, Sunkyu Kim, David Komander, Sylvie Urbe, Michael J Clague, Benedikt M Kessler, Axel Behrens

Get full text