Topoisomerase II Poisons for Glioblastoma; Existing Challenges and Opportunities to Personalize Therapy by Amol Mehta, Chidiebere U. Awah, Adam M. Sonabend

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Cell-Based Therapies for the Treatment of Traumatic Brain Injury: Promises and Trajectories by Karl J. Habashy, Saad Omais, Benedikt Haupt, Adam M. Sonabend, Christopher S. Ahuja

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The possibility of cancer immune editing in gliomas. A critical review by Víctor A. Arrieta, Bernardo Cacho-Díaz, Junfei Zhao, Raul Rabadan, Li Chen, Adam M. Sonabend

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Myeloid Cell Classification and Therapeutic Opportunities Within the Glioblastoma Tumor Microenvironment in the Single Cell-Omics Era by Collin J. Larkin, Víctor A. Arrieta, Víctor A. Arrieta, Víctor A. Arrieta, Hinda Najem, Hinda Najem, Gongbo Li, Gongbo Li, Peng Zhang, Peng Zhang, Jason Miska, Jason Miska, Peiwen Chen, Peiwen Chen, Charles David James, Charles David James, Adam M. Sonabend, Adam M. Sonabend, Amy B. Heimberger, Amy B. Heimberger

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Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm by Hongxu Ding, Eugene F. Douglass, Adam M. Sonabend, Angeliki Mela, Sayantan Bose, Christian Gonzalez, Peter D. Canoll, Peter A. Sims, Mariano J. Alvarez, Andrea Califano

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Assessing the Safety of Craniotomy for Resection of Primary Central Nervous System Lymphoma: A Nationwide Inpatient Sample Analysis by Jonathan Yun, Jingyan Yang, Michael Cloney, Amol Mehta, Suprit Singh, Fabio Massaiti Iwamoto, Alfred I. Neugut, Alfred I. Neugut, Alfred I. Neugut, Adam M. Sonabend

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Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment by Víctor A. Arrieta, Crismita Dmello, Daniel J. McGrail, Daniel J. Brat, Catalina Lee-Chang, Amy B. Heimberger, Dhan Chand, Roger Stupp, Adam M. Sonabend

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Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma by David Hou, Hanxiao Wan, Hanxiao Wan, Joshua L. Katz, Si Wang, Brandyn A. Castro, Brandyn A. Castro, Gustavo I. Vazquez-Cervantes, Victor A. Arrieta, Silpol Dhiantravan, Hinda Najem, Aida Rashidi, Tzu-yi Chia, Tarlan Arjmandi, Tarlan Arjmandi, Jimena Collado, Leah Billingham, Aurora Lopez-Rosas, Yu Han, Adam M. Sonabend, Adam M. Sonabend, Amy B. Heimberger, Amy B. Heimberger, Peng Zhang, Peng Zhang, Jason Miska, Jason Miska, Catalina Lee-Chang, Catalina Lee-Chang

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IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM by Stephen Gottschalk, Maciej S Lesniak, Irina V Balyasnikova, Jason Miska, Catalina Lee-Chang, Markella Zannikou, Joseph T Duffy, Rebecca N Levine, Maggie Seblani, Qianli Liu, Aaron Presser, Victor A Arrieta, Christopher J Chen, Adam M Sonabend, Craig M Horbinski

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Repeated blood–brain barrier opening with a nine-emitter implantable ultrasound device in combination with carboplatin in recurrent glioblastoma: a phase I/II clinical trial by Alexandre Carpentier, Roger Stupp, Adam M. Sonabend, Henry Dufour, Olivier Chinot, Bertrand Mathon, François Ducray, Jacques Guyotat, Nathalie Baize, Philippe Menei, John de Groot, Jeffrey S. Weinberg, Benjamin P. Liu, Eric Guemas, Carole Desseaux, Charlotte Schmitt, Guillaume Bouchoux, Michael Canney, Ahmed Idbaih

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STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma by Peng Zhang, Aida Rashidi, Junfei Zhao, Caylee Silvers, Hanxiang Wang, Brandyn Castro, Abby Ellingwood, Yu Han, Aurora Lopez-Rosas, Markella Zannikou, Crismita Dmello, Rebecca Levine, Ting Xiao, Alex Cordero, Adam M. Sonabend, Irina V. Balyasnikova, Catalina Lee-Chang, Jason Miska, Maciej S. Lesniak

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Single institution validation of a modified graded prognostic assessment of patients with breast cancer brain metastases by Cheng-Hung Tai, Cheng-Chia Wu, Mark E Hwang, Anurag Saraf, Christopher Grubb, Ashish Jani, Matthew E Lapa, Jacquelyn I S Andrews, Steven R Isaacson, Adam M Sonabend, Sameer A Sheth, Guy M McKhann, Michael B Sisti, Jeffrey N Bruce, Simon K Cheng, Eileen P Connolly, Tony JC Wang

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Patient-specific metrics of invasiveness reveal significant prognostic benefit of resection in a predictable subset of gliomas. by Anne L Baldock, Sunyoung Ahn, Russell Rockne, Sandra Johnston, Maxwell Neal, David Corwin, Kamala Clark-Swanson, Greg Sterin, Andrew D Trister, Hani Malone, Victoria Ebiana, Adam M Sonabend, Maciej Mrugala, Jason K Rockhill, Daniel L Silbergeld, Albert Lai, Timothy Cloughesy, Guy M McKhann, Jeffrey N Bruce, Robert C Rostomily, Peter Canoll, Kristin R Swanson

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Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade by Crismita Dmello, Junfei Zhao, Li Chen, Andrew Gould, Brandyn Castro, Victor A. Arrieta, Daniel Y. Zhang, Kwang-Soo Kim, Deepak Kanojia, Peng Zhang, Jason Miska, Ragini Yeeravalli, Karl Habashy, Ruth Saganty, Seong Jae Kang, Jawad Fares, Connor Liu, Gavin Dunn, Elizabeth Bartom, Matthew J. Schipma, Patrick D. Hsu, Mahmoud S. Alghamri, Maciej S. Lesniak, Amy B. Heimberger, Raul Rabadan, Catalina Lee-Chang, Adam M. Sonabend

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Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression by Hinda Najem, Martina Ott, Cynthia Kassab, Arvind Rao, Ganesh Rao, Anantha Marisetty, Adam M. Sonabend, Craig Horbinski, Roel Verhaak, Anand Shankar, Santhoshi N. Krishnan, Frederick S. Varn, Víctor A. Arrieta, Pravesh Gupta, Sherise D. Ferguson, Jason T. Huse, Gregory N. Fuller, James P. Long, Daniel E. Winkowski, Ben A. Freiberg, Charles David James, Leonidas C. Platanias, Maciej S. Lesniak, Jared K. Burks, Amy B. Heimberger

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Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas by Víctor A. Arrieta, Andrew Gould, Kwang-Soo Kim, Karl J. Habashy, Crismita Dmello, Gustavo I. Vázquez-Cervantes, Irina Palacín-Aliana, Graysen McManus, Christina Amidei, Cristal Gomez, Silpol Dhiantravan, Li Chen, Daniel Y. Zhang, Ruth Saganty, Meghan E. Cholak, Surya Pandey, Matthew McCord, Kathleen McCortney, Brandyn Castro, Rachel Ward, Miguel Muzzio, Guillaume Bouchoux, Carole Desseaux, Michael Canney, Alexandre Carpentier, Bin Zhang, Jason M. Miska, Maciej S. Lesniak, Craig M. Horbinski, Rimas V. Lukas, Roger Stupp, Catalina Lee-Chang, Adam M. Sonabend

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