Showing 1 - 20 results of 32 for search 'Adnan A. Kadi', query time: 0.08s Refine Results
  1. 1
    Liquid chromatography–tandem mass spectrometry metabolic profiling of nazartinib reveals the formation of unexpected reactive metabolites

    Liquid chromatography–tandem mass spectrometry metabolic profiling of nazartinib reveals the formation of unexpected reactive metabolites by Ali S. Abdelhameed, Mohamed W. Attwa, Adnan A. Kadi

    Published 2019-08-01
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  2. 2
    Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation

    Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation by Ali S. Abdelhameed, Mohamed W. Attwa, Adnan A. Kadi

    Published 2020-10-01
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  3. 3
    Solvent free Cannizzaro reaction applying grindstone technique

    Solvent free Cannizzaro reaction applying grindstone technique by A.F.M. Motiur Rahman, Adnan A. Kadi

    Published 2016-11-01
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  4. 4
    A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs

    A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs by Mohamed W. Attwa, Ali S. Abdelhameed, Adnan A. Kadi

    Published 2023-08-01
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  5. 5
    Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes

    Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes by Mohamed W. Attwa, Haitham AlRabiah, Adnan A. Kadi

    Published 2023-03-01
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  6. 6
    Editorial: Drug metabolism-induced organ toxicity

    Editorial: Drug metabolism-induced organ toxicity by Adnan A. Kadi, Yang Li, Abhinav Parashar, Mohamed W. Attwa

    Published 2024-01-01
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  7. 7
    An Ultrafast UPLC–MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib

    An Ultrafast UPLC–MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib by Mohamed W. Attwa, Ahmed H. Bakheit, Ali S. Abdelhameed, Adnan A. Kadi

    Published 2023-10-01
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  8. 8
    A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation

    A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation by Ali S. Abdelhameed, Mohamed W. Attwa, Nasser S. Al-Shaklia, Adnan A. Kadi

    Published 2019-06-01
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  9. 9
    A Rapid and Sensitive UPLC-MS/MS Method for Quantifying Capmatinib in Human Liver Microsomes: Evaluation of Metabolic Stability by In Silico and In Vitro Analysis

    A Rapid and Sensitive UPLC-MS/MS Method for Quantifying Capmatinib in Human Liver Microsomes: Evaluation of Metabolic Stability by In Silico and In Vitro Analysis by Mohamed W. Attwa, Ali S. Abdelhameed, Aishah M. Alsibaee, Adnan A. Kadi

    Published 2023-04-01
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  10. 10
    Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability.

    Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability. by Ali S Abdelhameed, Adnan A Kadi, Mohamed W Attwa, Haitham AlRabiah

    Published 2019-01-01
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  11. 11
    A Fast LC-MS/MS Methodology for Estimating Savolitinib in Human Liver Microsomes: Assessment of Metabolic Stability Using In Vitro Metabolic Incubation and In Silico Software Analysis

    A Fast LC-MS/MS Methodology for Estimating Savolitinib in Human Liver Microsomes: Assessment of Metabolic Stability Using In Vitro Metabolic Incubation and In Silico Software Analy... by Mohamed W. Attwa, Haitham AlRabiah, Ali S. Abdelhameed, Adnan A. Kadi

    Published 2023-08-01
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  12. 12
    Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms

    Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isof... by A. F. M. Motiur Rahman, Wencui Yin, Adnan A. Kadi, Yurngdong Jahng

    Published 2020-12-01
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  13. 13
    Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability.

    Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability. by Adnan A Kadi, Hany W Darwish, Mohamed W Attwa, Sawsan M Amer

    Published 2016-01-01
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  14. 14
    A Validated LC–MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation

    A Validated LC–MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation by Mohamed W. Attwa, Hany W. Darwish, Nasser S. Al-Shakliah, Adnan A. Kadi

    Published 2021-05-01
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  15. 15
    A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones

    A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones by Yurngdong Jahng, A. F. M. Motiur Rahman, Roushown Ali, Adnan A. Kadi

    Published 2012-01-01
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  16. 16
    Structural Analysis and Reactivity Insights of (<i>E</i>)-Bromo-4-((4-((1-(4-chlorophenyl)ethylidene)amino)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-5-((2-isopropylcyclohexyl)oxy) Furan-2(5H)-one: A Combined Approach Using Single-Crystal X-ray Diffraction, Hirshfeld Surface Analysis, and Conceptual Density Functional Theory

    Structural Analysis and Reactivity Insights of (<i>E</i>)-Bromo-4-((4-((1-(4-chlorophenyl)ethylidene)amino)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-5-((2-isopropylcyclohexyl)oxy) Fura... by Ahmed H. Bakheit, Mohamed W. Attwa, Adnan A. Kadi, Hamad M. Alkahtani

    Published 2023-08-01
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  17. 17
    In Vitro and Reactive Metabolites Investigation of Metabolic Profiling of Tyrosine Kinase Inhibitors Dubermatinib in HLMs by LC–MS/MS

    In Vitro and Reactive Metabolites Investigation of Metabolic Profiling of Tyrosine Kinase Inhibitors Dubermatinib in HLMs by LC–MS/MS by Nasser S. Al-Shakliah, Adnan A. Kadi, Hatem A. Abuelizz, Rashad Al-Salahi

    Published 2023-06-01
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  18. 18
    Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry

    Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry by Adnan A. Kadi, Sawsan M. Amer, Hany W. Darwish, Mohamed W. Attwa

    Published 2018-05-01
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  19. 19
    LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate

    LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate by Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish, Mohamed W. Attwa

    Published 2017-12-01
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  20. 20
    Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening

    Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening by Mohamed W. Attwa, Haitham AlRabiah, Gamal A. E. Mostafa, Adnan A. Kadi

    Published 2023-10-01
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