Systematic Review of Single-Agent vs. Multi-Agent Chemotherapy for Advanced Pancreatic Adenocarcinoma in Elderly vs. Younger Patients by Alison Lewis, Adnan Nagrial

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Small-Cell Lung Cancer—An Update on Targeted and Immunotherapies by Nicholas McNamee, Ines Pires da Silva, Adnan Nagrial, Bo Gao

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522 Transcriptomic changes in cancer patients treated with immune-checkpoint inhibitors by Golo Ahlenstiel, Adnan Nagrial, Dmitrii Shek, Joey Lai, Won-Hee Yoon, Tania Moujaber, Scott Read

Use of durvalumab in stage III non‐small‐cell lung cancer based on eligibility for the PACIFIC study by Emma Boys, Bo Gao, Rina Hui, Inês daSilva, Eric Hau, Harriet Gee, Adnan Nagrial

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177 Exploring the relationship between tumour heterogeneity and response to immunotherapy in malignant pleural mesothelioma by Golo Ahlenstiel, Matteo Carlino, Bo Gao, Adnan Nagrial, Hema Mahajan, Fabio Luciani, Dmitrii Shek, Scott Read

Immune-Checkpoint Inhibitors for Metastatic Colorectal Cancer: A Systematic Review of Clinical Outcomes by Dmitrii Shek, Liia Akhuba, Matteo S. Carlino, Adnan Nagrial, Tania Moujaber, Scott A. Read, Bo Gao, Golo Ahlenstiel

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Five‐year survival and clinical correlates among patients with advanced non‐small cell lung cancer, melanoma and renal cell carcinoma treated with immune check‐point inhibitors in... by Lauren J Brown, Ines Pires da Silva, Tania Moujaber, Bo Gao, Rina Hui, Howard Gurney, Matteo Carlino, Adnan Nagrial

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Can adjuvant pelvic radiation therapy after local excision or polypectomy for T1 and T2 rectal cancer offer an alternative option to radical surgery? by Carmen Swanton, Sapna Marcus, Jayasingham Jayamohan, Nimalan Pathma-Nathan, Toufic El-Khoury, Mark Wong, Adnan Nagrial, Drew Latty, Puma Sundaresan

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Elevated neutrophil‐to‐lymphocyte ratio (NLR) is associated with poorer progression‐free survival in unresectable stage III NSCLC treated with consolidation durvalumab by Udit Nindra, Adel Shahnam, Samuel Stevens, Abhijit Pal, Adnan Nagrial, Jenny Lee, Po Yee Yip, Tamiem Adam, Michael Boyer, Steven Kao, Victoria Bray

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Activin-A, Growth Differentiation Factor-11 and Transforming Growth Factor-β as predictive biomarkers for platinum chemotherapy in advanced non-small cell lung cancer by Jennifer Lim, Alexander Murphy, Stephen Wong, Adnan Nagrial, Deme Karikios, Dariush Daneshvar, Rachael McCloy, Angela M Steinmann, Sandra O'Toole, Venessa Chin

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Identification and Characterisation of Infiltrating Immune Cells in Malignant Pleural Mesothelioma Using Spatial Transcriptomics by Dmitrii Shek, Brian Gloss, Joey Lai, Li Ma, Hui E. Zhang, Matteo S. Carlino, Hema Mahajan, Adnan Nagrial, Bo Gao, Scott A. Read, Golo Ahlenstiel

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384 A Phase 1 study to evaluate the safety, PK, and antitumor activity of AK117, an anti-CD47 monoclonal antibody, in subjects with relapsed/refractory advanced or metastatic solid... by Yu Xia, Hui Gan, Xiaoping Jin, Amy Prawira, Jermaine Coward, Anna Mislang, Adnan Nagrial, Baiyong Li, Zhongmin Maxwell Wang, Kon Yew Kwek, Dennis Xia

Phase 1a dose escalation study of ivonescimab (AK112/SMT112), an anti-PD-1/VEGF-A bispecific antibody, in patients with advanced solid tumors by Wenjing Wang, Yu Xia, Charlotte Lemech, Adnan Nagrial, Baiyong Li, Zhongmin Maxwell Wang, Sophia Frentzas, Anna Rachelle Austria Mislang, Craig Underhill, Jermaine I G Coward

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Systematic Review of Preoperative Prognostic Biomarkers in Perihilar Cholangiocarcinoma by Rishaan Pawaskar, Kevin Zhang Huang, Helen Pham, Adnan Nagrial, Mark Wong, Siobhan O’Neill, Henry Pleass, Lawrence Yuen, Vincent W. T. Lam, Arthur Richardson, Tony Pang, Christopher B. Nahm

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First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study by Lauren Julia Brown, Lauren Julia Brown, Lauren Julia Brown, Lauren Julia Brown, Victor Khou, Victor Khou, Victor Khou, Chris Brown, Marliese Alexander, Marliese Alexander, Dasantha Jayamanne, Dasantha Jayamanne, Dasantha Jayamanne, Joe Wei, Lauren Gray, Wei Yen Chan, Wei Yen Chan, Samuel Smith, Susan Harden, Susan Harden, Antony Mersiades, Antony Mersiades, Lydia Warburton, Lydia Warburton, Malinda Itchins, Malinda Itchins, Malinda Itchins, Jenny H. Lee, Jenny H. Lee, Nick Pavlakis, Nick Pavlakis, Nick Pavlakis, Stephen J. Clarke, Stephen J. Clarke, Stephen J. Clarke, Michael Boyer, Michael Boyer, Adnan Nagrial, Adnan Nagrial, Adnan Nagrial, Eric Hau, Eric Hau, Eric Hau, Eric Hau, Ines Pires da Silva, Ines Pires da Silva, Ines Pires da Silva, Steven Kao, Steven Kao, Benjamin Y. Kong, Benjamin Y. Kong, Benjamin Y. Kong, Benjamin Y. Kong

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Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma by Jordan F Hastings, Alvaro Gonzalez Rajal, Sharissa L Latham, Jeremy ZR Han, Rachael A McCloy, Yolande EI O'Donnell, Monica Phimmachanh, Alexander D Murphy, Adnan Nagrial, Dariush Daneshvar, Venessa Chin, D Neil Watkins, Andrew Burgess, David R Croucher

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LOREALAUS: LOrlatinib REAL-World AUStralian Experience in Advanced ALK-Rearranged NSCLC by Marliese Alexander, B.Pharm(Hons), MPH, PhD, Joe Wei, MD, Sagun Parakh, MD, Thomas John, MD, Steven Kao, MD, Adnan Nagrial, MD, Samantha Bowyer, MD, Lydia Warburton, MD, Melissa Moore, MD, Brett G.M. Hughes, MD, Timothy D. Clay, MD, Nick Pavlakis, MD, Benjamin J. Solomon, MD, Malinda Itchins, MD

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Retrospective Evaluation of the Use of Pembrolizumab in Malignant Mesothelioma in a Real-World Australian Population by Tamkin Ahmadzada, BE, Wendy A. Cooper, BScMed, M.B.B.S., PhD, FRCPA, Mikaela Holmes, BBiomedSc, Annabelle Mahar, M.B.B.S., FRCPA, Helen Westman, MPH, Anthony J. Gill, MD, FRCPA, Ina Nordman, M.B.B.S., FRACP, M(Med)Sc, Po Yee Yip, MbChB., FRACP, PhD, Abhijit Pal, BSc (Hons), M.B.B.S., FRACP, Rob Zielinski, FRACP, M.B.B.S., Hons, Nick Pavlakis, BSc, M.B.B.S., MMed (Clin Epi), PhD, FRACP, Adnan Nagrial, M.B.B.S., PhD, Dariush Daneshvar, MD, FRCPA, Daniel Brungs, M.B.B.S., MMed (Clin Epi), FRCPA, Deme Karikios, BSc, M.B.B.S., FRACP, PhD, Vesna Aleksova, BMedSc, Juliet Burn, M.B.B.S., FRCPA, MIAC, Rebecca Asher, MSc, Georges E. Grau, MD, PhD, Elham Hosseini-Beheshti, MSc, PhD, Glen Reid, PhD, Stephen Clarke, MD, PhD, FRACP, Steven Kao, BHB, MbChB., PhD, FRACP

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