New lives for old: evolution of pseudoenzyme function illustrated by iRhoms. por Adrain, C, Freeman, M

Regulation of receptor tyrosine kinase ligand processing. por Adrain, C, Freeman, M

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. por Adrain, C, Zettl, M, Christova, Y, Taylor, N, Freeman, M

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation por Christova, Y, Adrain, C, Bambrough, P, Ibrahim, A, Freeman, M

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation. por Christova, Y, Adrain, C, Bambrough, P, Ibrahim, A, Freeman, M

Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. por Zettl, M, Adrain, C, Strisovsky, K, Lastun, V, Freeman, M

Mammalian EGF receptor activation by the rhomboid protease RHBDL2. por Adrain, C, Strisovsky, K, Zettl, M, Hu, L, Lemberg, M, Freeman, M

New efficient, practical method for producing ‘Compreg’ OPW through integrated objective approach por Bakar, Edi Suhaimi, Abare, Al-Hasan Yakubu, Yong, Adrain C. C., Ashaari, Zaidon

Obter o texto integral

Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis por Johnson, N, Březinová, J, Stephens, E, Burbridge, E, Freeman, M, Adrain, C, Strisovsky, K

EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel por Gaspar, CJ, Vieira, LC, Santos, CC, Christianson, JC, Jakubec, D, Strisovsky, K, Adrain, C, Domingos, PM

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα por Wunderle, L, Knopf, J, Kühnle, N, Morlé, A, Hehn, B, Adrain, C, Strisovsky, K, Freeman, M, Lemberg, M