Adrian Krainer (scientist)

Krainer in 2018 Adrian Robert Krainer is a Uruguayan-American biochemist and molecular geneticist known for his research into RNA gene-splicing. He helped create a drug for patients with spinal muscular atrophy. Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory in Laurel Hollow, New York. Provided by Wikipedia
Showing 1 - 12 results of 12 for search 'Adrian R. Krainer', query time: 0.04s Refine Results
  1. 1
    Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC

    Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC by Shipra Das, Olga Anczuków, Martin Akerman, Adrian R. Krainer

    Published 2012-02-01
    Get full text
    Article
  2. 2
    Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor

    Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor by Juergen Scharner, Sabrina Qi, Frank Rigo, C. Frank Bennett, Adrian R. Krainer

    Published 2019-06-01
    Get full text
    Article
  3. 3
    Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy

    Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy by Young Jin Kim, Tomoki Nomakuchi, Foteini Papaleonidopoulou, Lucia Yang, Qian Zhang, Adrian R. Krainer

    Published 2022-05-01
    Get full text
    Article
  4. 4
    Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).

    Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). by Michelle L Hastings, Eric Allemand, Dominik M Duelli, Michael P Myers, Adrian R Krainer

    Published 2007-06-01
    Get full text
    Article
  5. 5
    Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.

    Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon. by Yimin Hua, Timothy A Vickers, Brenda F Baker, C Frank Bennett, Adrian R Krainer

    Published 2007-04-01
    Get full text
    Article
  6. 6
    Identification of synaptic targets of Drosophila pumilio.

    Identification of synaptic targets of Drosophila pumilio. by Gengxin Chen, Wanhe Li, Qing-Shuo Zhang, Michael Regulski, Nishi Sinha, Jody Barditch, Tim Tully, Adrian R Krainer, Michael Q Zhang, Josh Dubnau

    Published 2008-02-01
    Get full text
    Article
  7. 7
    Specificity, synergy, and mechanisms of splice-modifying drugs

    Specificity, synergy, and mechanisms of splice-modifying drugs by Yuma Ishigami, Mandy S. Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M. Hanson, David M. McCandlish, Adrian R. Krainer, Justin B. Kinney

    Published 2024-02-01
    Get full text
    Article
  8. 8
    Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia

    Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia by Masahiko Ajiro, Tomonari Awaya, Young Jin Kim, Kei Iida, Masatsugu Denawa, Nobuo Tanaka, Ryo Kurosawa, Shingo Matsushima, Saiko Shibata, Tetsunori Sakamoto, Rolenz Studer, Adrian R. Krainer, Masatoshi Hagiwara

    Published 2021-07-01
    Get full text
    Article
  9. 9
    Author Correction: Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia

    Author Correction: Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia by Masahiko Ajiro, Tomonari Awaya, Young Jin Kim, Kei Iida, Masatsugu Denawa, Nobuo Tanaka, Ryo Kurosawa, Shingo Matsushima, Saiko Shibata, Tetsunori Sakamoto, Lorenz Studer, Adrian R. Krainer, Masatoshi Hagiwara

    Published 2021-10-01
    Get full text
    Article
  10. 10
    HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism

    HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism by Sebastien M. Weyn-Vanhentenryck, Aldo Mele, Qinghong Yan, Shuying Sun, Natalie Farny, Zuo Zhang, Chenghai Xue, Margaret Herre, Pamela A. Silver, Michael Q. Zhang, Adrian R. Krainer, Robert B. Darnell, Chaolin Zhang

    Published 2014-03-01
    Get full text
    Article
  11. 11
    Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

    Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis by SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura Urbanski, Adam Geier, Anil K. Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K. Muthuswamy, Adrian R. Krainer, Olga Anczuków

    Published 2019-11-01
    Get full text
    Article
  12. 12
    Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

    Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers by Manaswini Sivaramakrishnan, Kathleen D. McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N. Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R. Krainer, Frédéric H.-T. Allain, Friedrich Metzger

    Published 2017-11-01
    Get full text
    Article

Search Tools: