ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response. by Weston, R, Peeters, H, Ahel, D

Structural insights into the function of ZRANB3 in replication stress response by Sebesta, M, Cooper, C, Ariza, A, Carnie, C, Ahel, D

Selective inhibition of divergent seryl-tRNA synthetases by serine analogues. by Ahel, D, Slade, D, Mocibob, M, Söll, D, Weygand-Durasevic, I

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. by Ahel, I, Ahel, D, Matsusaka, T, Clark, A, Pines, J, Boulton, S, West, S

Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential by Rack, JGM, Zorzini, V, Zhu, Z, Schuller, M, Ahel, D, Ahel, I

Structure of the unusual seryl-tRNA synthetase reveals a distinct zinc-dependent mode of substrate recognition. by Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Söll, D, Weygand-Durasevic, I, Ban, N

DNA repair factor APLF is a histone chaperone. by Mehrotra, P, Ahel, D, Ryan, D, Weston, R, Wiechens, N, Kraehenbuehl, R, Owen-Hughes, T, Ahel, I

DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates by Zhu, K, Suskiewicz, MJ, Hloušek-Kasun, A, Meudal, H, Mikoč, A, Aucagne, V, Ahel, D, Ahel, I

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. by Ahel, D, Horejsí, Z, Wiechens, N, Polo, SE, Garcia-Wilson, E, Ahel, I, Flynn, H, Skehel, M, West, S, Jackson, S, Owen-Hughes, T, Boulton, S

HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation by Suskiewicz, MJ, Zobel, F, Ogden, TEH, Fontana, P, Ariza, A, Yang, J-C, Zhu, K, Bracken, L, Hawthorne, WJ, Ahel, D, Neuhaus, D, Ahel, I

Serine-linked PARP1 auto-modification controls PARP inhibitor response. by Prokhorova, E, Zobel, F, Smith, R, Zentout, S, Gibbs-Seymour, I, Schützenhofer, K, Peters, A, Groslambert, J, Zorzini, V, Agnew, T, Brognard, J, Nielsen, ML, Ahel, D, Huet, S, Suskiewicz, MJ, Ahel, I

Updated protein domain annotation of the PARP protein family sheds new light on biological function by Suskiewicz, MJ, Munnur, D, Strømland, Ø, Yang, J-C, Easton, LE, Chatrin, C, Zhu, K, Baretić, D, Goffinont, S, Schuller, M, Wu, W-F, Elkins, JM, Ahel, D, Sanyal, S, Neuhaus, D, Ahel, I

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal by Rack, JGM, Liu, Q, Zorzini, V, Voorneveld, J, Ariza, A, Honarmand Ebrahimi, K, Reber, JM, Krassnig, SC, Ahel, D, van der Marel, GA, Mangerich, A, McCullagh, JSO, Filippov, DV, Ahel, I

PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation by Kar, P, Chatrin, C, Đukić, N, Suyari, O, Schuller, M, Zhu, K, Prokhorova, E, Bigot, N, Ahel, J, Elsborg, JD, Nielsen, ML, Clausen, T, Huet, S, Niepel, M, Sanyal, S, Ahel, D, Smith, R, Ahel, I

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease by Prokhorova, E, Agnew, T, Wondisford, AR, Tellier, M, Kaminski, N, Beijer, D, Holder, J, Groslambert, J, Suskiewicz, MJ, Zhu, K, Reber, JM, Krassnig, SC, Palazzo, L, Murphy, S, Nielsen, ML, Mangerich, A, Ahel, D, Baets, J, O'Sullivan, RJ, Ahel, I

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD by Hewitt, G, Borel, V, Segura-Bayona, S, Takaki, T, Ruis, P, Bellelli, R, Lehmann, LC, Sommerova, L, Vancevska, A, Tomas-Loba, A, Zhu, K, Cooper, C, Fugger, K, Patel, H, Goldstone, R, Schneider-Luftman, D, Herbert, E, Stamp, G, Brough, R, Pettitt, S, Lord, CJ, West, SC, Ahel, I, Ahel, D, Chapman, JR, Deindl, S, Boulton, SJ

Cellular and biochemical characterisation of ERCC6L2 by Armstrong, L

Other Authors: “…Ahel, D…”