Models of Variability and Circadian Rhythm in Heart Rate, Blood Pressure, and QT Interval for Healthy Subjects Who Received Placebo in Phase I Trials 由 Mukul Minocha, Hong Li, Yi‐Lin Chiu, David Carter, Ahmed A. Othman

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Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers 由 Ganesh Cherala, Cara Nelson, Ying Guo, Anubhav Mathur, Thomas Tarnowski, Ahmed A. Othman

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Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers 由 Islam R. Younis, Brian J. Kirby, Andrew N. Billin, Deqing Xiao, Qinghua Song, Timothy R. Watkins, Ahmed A. Othman

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Pharmacokinetics, pharmacodynamics, and safety of GS‐3583, a FLT3 agonist Fc fusion protein, from single‐ascending‐dose phase I study in healthy participants 由 Anees M. Dauki, Nishanthan Rajakumaraswamy, Torsten Trowe, Winnie Weng, Kai‐Wen Lin, Emon Elboudjwarej, Ann Ran‐Ran Qin, Christian Schwabe, Michelle R. Kuhne, Ahmed A. Othman

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Phase 1 first-in-human study of dalutrafusp alfa, an anti–CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors 由 Michael Gordon, Anthony W Tolcher, James Strauss, Marianna Zavodovskaya, Anna Seto, Tianling Chen, Susanna Stinson, Kathleen M Mahoney, Chia-Hsiang Hsueh, Shuyan Zhai, Thomas Tarnowski, Juliane M Jürgensmeier, Ahmed A Othman

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Oral PD-L1 inhibitor GS-4224 selectively engages PD-L1 high cells and elicits pharmacodynamic responses in patients with advanced solid tumors 由 Nicholas Waldron, P Rod Dunbar, Sanjeev Deva, Oh Kyu Yoon, John Ling, Kai-Wen Lin, Dung Thai, Latesh Lad, Ahmed A Othman, Jared M Odegard, Adele Y Wang, Jonathan Nazareno, Edmond Ang

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