Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-ones by Mohamed-Kamal Ibrahim, Khaled El-Adl, Ahmed A. Al-Karmalawy

Get full text

Chemical and biological assessment of Alternaria alternata as an endophytic fungus isolated from Thymus vulgaris by Aml Ghanem, Ahmed A. Al-Karmalawy, Noha E. Morsy, Mahmoud Elsabahy, Ahmed M. Rayan

Get full text

Pyridazine Based Compounds with PARP-1 Inhibitory Activity by Norhan A. Abdelrahman, Mai Y. Jaballah, Ahmed A. Al-Karmalawy, Khaled A. M. Abouzid

Get full text

A Comprehensive Overview of Organ Inflammatory Responses: Genesis, Possible Mechanisms, and Mediators of Inflammation by Samar A. Antar, Ayman M. Mahmoud, Walied Abdo, Cherry Gad, Ahmed A. Al-Karmalawy

Get full text

Editorial: Recent advances in the research and development of kinase-inhibitory anticancer molecules by Ahmed A. Al-Karmalawy, Ahmed A. Al-Karmalawy, Hussein I. El-Subbagh, Hussein I. El-Subbagh, Liliya Logoyda, Roman B. Lesyk, Mohammed I. El-Gamal, Mohammed I. El-Gamal, Mohammed I. El-Gamal

Get full text

Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from Jasminum humile by Khaled Ahmed Mansour, Ahmed Elbermawi, Ahmed A. Al-Karmalawy, Mohamed-Farid Lahloub, Mona El-Neketi

Get full text

Nanobiotechnological Approaches to Enhance Potato Resistance against Potato Leafroll Virus (PLRV) Using Glycyrrhizic Acid Ammonium Salt and Salicylic Acid Nanoparticles by Tahsin Shoala, Ahmed A. Al-Karmalawy, Mousa O. Germoush, Salha M. ALshamrani, Mohamed A. Abdein, Nabil S. Awad

Get full text

Potential Valorization of Edible Nuts By-Products: Exploring the Immune-Modulatory and Antioxidants Effects of Selected Nut Shells Extracts in Relation to Their Metabolic Profiles by Mohamed A. Salem, Nora M. Aborehab, Ahmed A. Al-Karmalawy, Alisdair R. Fernie, Saleh Alseekh, Shahira M. Ezzat

Get full text

Metabolites profiling, in-vitro and molecular docking studies of five legume seeds for Alzheimer’s disease by Rana M. Ibrahim, Passent M. Abdel-Baki, Osama G. Mohamed, Ahmed A. Al-Karmalawy, Ashootosh Tripathi, Riham A. El-Shiekh

Get full text

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protea... by Mohamed Elagawany, Ayman Abo Elmaaty, Ahmed Mostafa, Noura M. Abo Shama, Eman Y. Santali, Bahaa Elgendy, Ahmed A. Al-Karmalawy

Get full text

In Silico Prediction of a Multitope Vaccine against <i>Moraxella catarrhalis</i>: Reverse Vaccinology and Immunoinformatics by Mohamed A. Soltan, Nada Elbassiouny, Helmy Gamal, Eslam B. Elkaeed, Refaat A. Eid, Muhammad Alaa Eldeen, Ahmed A. Al-Karmalawy

Get full text

Identification of Ureidocoumarin-Based Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors via Drug Repurposing Approach, Biological Evaluation, and In Silico Studies by Ashraf K. El-Damasy, Hyun Ji Kim, Ahmed A. Al-Karmalawy, Radwan Alnajjar, Mohamed M. Khalifa, Eun-Kyoung Bang, Gyochang Keum

Get full text

Design of new captopril mimics as promising ACE inhibitors: ADME, pharmacophore, molecular docking and dynamics simulation with MM-PBSA and PCA calculations by Amany Belal, Mohamed A. Elanany, Ahmed A. Al-Karmalawy, Ahmed Elkamhawy, Mohammed A. S. Abourehab, Heba I. Ghamry, Ahmed B. M. Mehany

Get full text

Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers by Samar El-Kalyoubi, Mohamed M. Khalifa, Mahmoud T. Abo-Elfadl, Ahmed A. El-Sayed, Ahmed Elkamhawy, Kyeong Lee, Ahmed A. Al-Karmalawy

Get full text

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors by Amany Belal, Nagwa M. Abdel Gawad, Ahmed B. M. Mehany, Mohammed A. S. Abourehab, Hazem Elkady, Ahmed A. Al‐Karmalawy, Ahmed S. Ismael

Get full text

Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead Optimization by Ayman Abo Elmaaty, Mohammed I. A. Hamed, Muhammad I. Ismail, Eslam B. Elkaeed, Hamada S. Abulkhair, Muhammad Khattab, Ahmed A. Al-Karmalawy

Get full text

Synthesis of New Organoselenium-Based Succinanilic and Maleanilic Derivatives and In Silico Studies as Possible SARS-CoV-2 Main Protease Inhibitors by Saad Shaaban, Yasair S. Al-Faiyz, Ghayah M. Alsulaim, Mohamed Alaasar, Nasser Amri, Hussein Ba-Ghazal, Ahmed A. Al-Karmalawy, Aly Abdou

Get full text

Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter by Amany Belal, Mohammed S. Elballal, Ahmed A. Al-Karmalawy, Ahmed A. Al-Karmalawy, Ahmed H. E. Hassan, Eun Joo Roh, Eun Joo Roh, Mohammed M. Ghoneim, Mohamed A. M. Ali, Mohamed A. M. Ali, Ahmad J. Obaidullah, Jawaher M. Alotaibi, Salwa Shaaban, Salwa Shaaban, Mohamed A. Elanany

Get full text

In Silico and In Vivo Evaluation of SARS-CoV-2 Predicted Epitopes-Based Candidate Vaccine by Mahmoud M. Shehata, Sara H. Mahmoud, Mohammad Tarek, Ahmed A. Al-Karmalawy, Amal Mahmoud, Ahmed Mostafa, Mahmoud M. Elhefnawi, Mohamed A. Ali

Get full text

Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations by Amany Belal, Aly Abdou, Samar F. Miski, Mohamed A. M. Ali, Heba I. Ghamry, Ahmad J. Obaidullah, Ahmad J. Obaidullah, Mohamed Y. Zaky, Ahmed H. E. Hassan, Ahmed H. E. Hassan, Eun Joo Roh, Eun Joo Roh, Ahmed A. Al-Karmalawy, Ahmed A. Al-Karmalawy, Mona H. Ibrahim

Get full text