Mendelian randomization in cardiometabolic disease: challenges in evaluating causality af Holmes, M, Ala-Korpela, M, Smith, G

Genetic support for a causal role of insulin resistance on circulating branched-chain amino acids and inflammation af Wang, Q, Holmes, M, Davey Smith, G, Ala-Korpela, M

A phenome-wide bidirectional Mendelian randomization analysis of atrial fibrillation af Wang, Q, Richardson, TG, Sanderson, E, Tudball, MJ, Ala-Korpela, M, Davey Smith, G, Holmes, MV

DHA mediates the protective effect of fish consumption on new episodes of depression among women af Reeves, J, Otahal, P, Magnussen, C, Dwyer, T, Kangas, A, Soininen, P, Ala-Korpela, M, Venn, A, Smith, K

Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study: Metabolism af Preiss, D, Rankin, N, Welsh, P, Holman, R, Kangas, A, Soininen, P, Würtz, P, Ala-Korpela, M, Sattar, N

Low-grade, systemic inflammation in adolescents: association with early-life factors, gender, and lifestyle. af Pirkola, J, Vääräsmäki, M, Ala-Korpela, M, Bloigu, A, Canoy, D, Hartikainen, A, Leinonen, M, Miettola, S, Paldanius, M, Tammelin, T, Järvelin, MR, Pouta, A

Circulating amino acids and the risk of macrovascular, microvascular and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial af Welsh, P, Rankin, N, Li, Q, Mark, P, Würtz, P, Ala-Korpela, M, Marre, M, Poulter, N, Hamet, P, Chalmers, J, Woodward, M, Sattar, N

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis af Wang, Q, Oliver-Williams, C, Raitakari, OT, Viikari, J, Lehtimäki, T, Kähönen, M, Järvelin, M-R, Salomaa, V, Perola, M, Danesh, J, Kettunen, J, Butterworth, AS, Holmes, MV, Ala-Korpela, M

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study af Karjalainen, MK, Holmes, MV, Wang, Q, Anufrieva, O, Kähönen, M, Lehtimäki, T, Havulinna, AS, Kristiansson, K, Salomaa, V, Perola, M, Viikari, JS, Raitakari, OT, Järvelin, M-R, Ala-Korpela, M, Kettunen, J

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics af Tynkkynen, T, Wang, Q, Ekholm, J, Anufrieva, O, Ohukainen, P, Vepsäläinen, J, Männikkö, M, Keinänen-Kiukaanniemi, S, Holmes, M, Goodwin, M, Ring, S, Chambers, J, Kooner, J, Järvelin, M, Kettunen, J, Hill, M, Davey Smith, G, Ala-Korpela, M

Lipids, lipoproteins and metabolites and risk of incident myocardial infarction and stroke subtypes af Holmes, M, Millwood, I, Kartsonaki, C, Hill, M, Bennett, D, Boxall, R, Guo, Y, Xu, X, Bian, Z, Hu, R, Walters, R, Chen, J, Ala-Korpela, M, Parish, S, Clarke, R, Peto, R, Collins, R, Li, L, Chen, Z

A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease af Prokić, I, Lahousse, L, de Vries, M, Liu, J, Kalaoja, M, Vonk, JM, van der Plaat, DA, van Diemen, CC, van der Spek, A, Zhernakova, A, Fu, J, Ghanbari, M, Ala-Korpela, M, Kettunen, J, Havulinna, AS, Perola, M, Salomaa, V, Lind, L, Ärnlöv, J, Stricker, BHC, Brusselle, GG, Boezen, HM, van Duijn, CM, Amin, N

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment af Sliz, E, Kettunen, J, Holmes, MV, Williams, CO, Boachie, C, Wanq, Q, Mänikkö, M, Sebert, S, Walters, R, Lin, K, Millwood, IY, Clarke, RJ, Li, L, Rankin, N, Welsh, P, Delles, C, Jukema, JW, Trompet, S, Ford, I, Perola, M, Salomaa, V, Järvelin, M-R, Chen, Z, Lawlor, DA, Ala-Korpela, M, Danesh, J, Smith, GD, Sattar, N, Butterworth, A, Würtz, P

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study af Chambers, JC, Loh, M, Lehne, B, Drong, A, Kriebel, J, Motta, V, Wahl, S, Elliott, HR, Rota, F, Scott, WR, Zhang, W, Tan, S-T, Campanella, G, Chadeau-Hyam, M, Yengo, L, Richmond, RC, Adamowicz-Brice, M, Afzal, U, Bozaoglu, K, Mok, ZY, Ng, HK, Pattou, F, Prokisch, H, Rozario, MA, Tarantini, L, Abbott, J, Ala-Korpela, M, Albetti, B, Ammerpohl, O, Bertazzi, PA, Blancher, C, Caiazzo, R, Danesh, J, Gaunt, TR, de Lusignan, S, Gieger, C, Illig, T, Jha, S, Jones, S, Jowett, J, Kangas, AJ, Kasturiratne, A, Kato, N, Kotea, N, Kowlessur, S, Pitkäniemi, J, Punjabi, P, Saleheen, D, Schafmayer, C, Soininen, P, Tai, ES, Thorand, B, Tuomilehto, J, Wickremasinghe, AR, Kyrtopoulos, SA, Aitman, TJ, Herder, C, Hampe, J, Cauchi, S, Relton, CL, Froguel, P, Soong, R, Vineis, P, Jarvelin, MR, Scott, J, Grallert, H, Bollati, V, Elliott, P, McCarthy, MI, Kooner, JS

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. af Surakka, I, Isaacs, A, Karssen, L, Laurila, P, Middelberg, R, Tikkanen, E, Ried, J, Lamina, C, Mangino, M, Igl, W, Hottenga, J, Lagou, V, van der Harst, P, Mateo Leach, I, Esko, T, Kutalik, Z, Wainwright, N, Struchalin, M, Sarin, A, Kangas, A, Viikari, J, Perola, M, Rantanen, T, Petersen, A, Soininen, P, Johansson, A, Soranzo, N, Heath, A, Papamarkou, T, Prokopenko, I, Tönjes, A, Kronenberg, F, Döring, A, Rivadeneira, F, Montgomery, G, Whitfield, J, Kähönen, M, Lehtimäki, T, Freimer, N, Willemsen, G, de Geus, E, Palotie, A, Sandhu, MS, Waterworth, D, Metspalu, A, Stumvoll, M, Uitterlinden, A, Jula, A, Navis, G, Wijmenga, C, Wolffenbuttel, B, Taskinen, MR, Ala-Korpela, M, Kaprio, J, Kyvik, K, Boomsma, D, Pedersen, N, Gyllensten, U, Wilson, J, Rudan, I, Campbell, H, Pramstaller, P, Spector, T, Witteman, J, Eriksson, J, Salomaa, V, Oostra, B, Raitakari, O, Wichmann, H, Gieger, C, Järvelin, MR, Martin, N, Hofman, A, McCarthy, M, Peltonen, L, van Duijn, C, Aulchenko, Y, Ripatti, S

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. af Wahl, S, Drong, A, Lehne, B, Loh, M, Scott, W, Kunze, S, Tsai, P, Ried, J, Zhang, W, Yang, Y, Tan, S, Fiorito, G, Franke, L, Guarrera, S, Kasela, S, Kriebel, J, Richmond, R, Adamo, M, Afzal, U, Ala-Korpela, M, Albetti, B, Ammerpohl, O, Apperley, J, Beekman, M, Bertazzi, P, Black, S, Blancher, C, Bonder, M, Brosch, M, Carstensen-Kirberg, M, de Craen, A, de Lusignan, S, Dehghan, A, Elkalaawy, M, Fischer, K, Franco, O, Gaunt, T, Hampe, J, Hashemi, M, Isaacs, A, Jenkinson, A, Jha, S, Kato, N, Krogh, V, Laffan, M, Meisinger, C, Meitinger, T, Mok, Z, Motta, V, Ng, H, Nikolakopoulou, Z, Nteliopoulos, G, Panico, S, Pervjakova, N, Prokisch, H, Rathmann, W, Roden, M, Rota, F, Rozario, M, Sandling, J, Schafmayer, C, Schramm, K, Siebert, R, Slagboom, P, Soininen, P, Stolk, L, Strauch, K, Tai, E, Tarantini, L, Thorand, B, Tigchelaar, E, Tumino, R, Uitterlinden, A, van Duijn, C, van Meurs, J, Vineis, P, Wickremasinghe, A, Wijmenga, C, Yang, T, Yuan, W, Zhernakova, A, Batterham, R, Smith, G, Deloukas, P, Heijmans, B, Herder, C, Hofman, A, Lindgren, C, Milani, L, van der Harst, P, Peters, A, Illig, T, Relton, C, Waldenberger, M, Järvelin, M, Bollati, V, Soong, R, Spector, T, Scott, J, McCarthy, M, Elliott, P, Bell, J, Matullo, G, Gieger, C, Kooner, J, Grallert, H, Chambers, J