H2AFZ: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment by Laura Bongiovanni, Anneloes Andriessen, Serenella Silvestri, Ilaria Porcellato, Chiara Brachelente, Alain de Bruin, Alain de Bruin

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Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma by Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog

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Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish by Suma Choorapoikayil, Bart Weijts, Rianne Kers, Alain de Bruin, Jeroen den Hertog

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Correction: Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4. by Bart G. M. W. Weijts, Andreas van Impel, Stefan Schulte-Merker, Alain de Bruin

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Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4. by Bart G M W Weijts, Andreas van Impel, Stefan Schulte-Merker, Alain de Bruin

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DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease by Bhagyashree S. Joshi, Sameh A. Youssef, Reinier Bron, Alain de Bruin, Harm H. Kampinga, Inge S. Zuhorn

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Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells by Inez Johanna, Trudy Straetemans, Sabine Heijhuurs, Tineke Aarts-Riemens, Håkan Norell, Laura Bongiovanni, Alain de Bruin, Zsolt Sebestyen, Jürgen Kuball

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Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice by Klaske M. Schukken, Yinan Zhu, Petra L. Bakker, Mirjam H. Koster, Liesbeth Harkema, Sameh A. Youssef, Alain de Bruin, Floris Foijer

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Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages. by Lei Deng, Lorena Itatí Ibañez, Veronique Van den Bossche, Kenny Roose, Sameh A Youssef, Alain de Bruin, Walter Fiers, Xavier Saelens

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Lack of major genome instability in tumors of p53 null rats. by Roel Hermsen, Pim Toonen, Ewart Kuijk, Sameh A Youssef, Raoul Kuiper, Sebastiaan van Heesch, Alain de Bruin, Edwin Cuppen, Marieke Simonis

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Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in HepatocytesSummary by Ali Saeed, Paulina Bartuzi, Janette Heegsma, Daphne Dekker, Niels Kloosterhuis, Alain de Bruin, Johan W. Jonker, Bart van de Sluis, Klaas Nico Faber

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Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals by Nainoa Richardson, Isabelle Gillot, Elodie P Gregoire, Sameh A Youssef, Dirk de Rooij, Alain de Bruin, Marie-Cécile De Cian, Marie-Christine Chaboissier

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Correction: Par1b Induces Asymmetric Inheritance of Plasma Membrane Domains via LGN-Dependent Mitotic Spindle Orientation in Proliferating Hepatocytes. by Christiaan L. Slim, Francisco Lázaro-Diéguez, Marjolein Bijlard, Mathilda J. M. Toussaint, Alain de Bruin, Quansheng Du, Anne Müsch, Sven C. D. van IJzendoorn

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Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes. by Christiaan L Slim, Francisco Lázaro-Diéguez, Marjolein Bijlard, Mathilda J M Toussaint, Alain de Bruin, Quansheng Du, Anne Müsch, Sven C D van Ijzendoorn

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Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage by Hendrika A. Segeren, Lotte M. van Rijnberk, Eva Moreno, Frank M. Riemers, Elsbeth A. van Liere, Ruixue Yuan, Richard Wubbolts, Alain de Bruin, Bart Westendorp

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Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context by Eva Moreno, Shusil K. Pandit, Mathilda J. M. Toussaint, Laura Bongiovanni, Liesbeth Harkema, Saskia C. van Essen, Elsbeth A. van Liere, Bart Westendorp, Alain de Bruin

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Atypical E2f functions are critical for pancreas polyploidization. by Ramadhan B Matondo, Eva Moreno, Mathilda J M Toussaint, Peter C J Tooten, Saskia C van Essen, Elsbeth A van Liere, Sameh A Youssef, Laura Bongiovanni, Alain de Bruin

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The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency. by Erwin Reiling, Martijn E T Dollé, Sameh A Youssef, Moonsook Lee, Bhawani Nagarajah, Marianne Roodbergen, Piet de With, Alain de Bruin, Jan H Hoeijmakers, Jan Vijg, Harry van Steeg, Paul Hasty

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Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia by Marcela Doktorova, Irene Zwarts, Tim van Zutphen, Theo H. van Dijk, Vincent W. Bloks, Liesbeth Harkema, Alain de Bruin, Michael Downes, Ronald M. Evans, Henkjan J. Verkade, Johan W. Jonker

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Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice by Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl

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