Prophylactic and Therapeutic Effect of Kynurenine for Experimental Autoimmune Encephalomyelitis (EAE) Disease by Gayathri Sundaram, Alban Bessede, David Gilot, Ananda Staats Pires, Larry S Sherman, Bruce J Brew, Gilles J Guillemin

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Phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced breast cancer by Sophie Cousin, Maud Toulmonde, Michèle Kind, Jean-Philippe Guegan, Alban Bessede, Coralie Cantarel, Carine Bellera, Antoine Italiano

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1132 Stimulated tumor cells (STC) vaccine induce response in colorectal cancer by Yan Wang, Antoine Italiano, Alban Bessede, Corinne Tortorelli, Benoit Pinteur, Lionel Chalus, Paul Bravetti, George Alzeeb, Arnaud Peyronnier

782-G The correlation of tumor immune microenvironment with response to neoadjuvant chemotherapy response in undifferentiated pleiomorphic sarcomas: an analysis of the NEOSARCOMICS... by Jean-Michel Coindre, Antoine Italiano, Maud Toulmonde, Alban Bessede, Florent Peyraud, Jean-Philippe Guégan, Lucile Vanhersecke, Julien Vibert, Mariella Spalato-Ceruso

Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas by Pilvi Maliniemi, Kirsi Laukkanen, Liisa Väkevä, Katja Dettmer, Tuomas Lipsanen, Leila Jeskanen, Alban Bessede, Peter J. Oefner, Marshall E. Kadin, Annamari Ranki

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Randomized phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced soft-tissue sarcoma by Maud Toulmonde, Sophie Cousin, Michèle Kind, Jean-Philippe Guegan, Alban Bessede, Francois Le Loarer, Raul Perret, Coralie Cantarel, Carine Bellera, Antoine Italiano

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Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives by Florent Peyraud, Florent Peyraud, Florent Peyraud, Jean-Philippe Guegan, Dominique Bodet, Sophie Cousin, Sophie Cousin, Alban Bessede, Antoine Italiano, Antoine Italiano, Antoine Italiano

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In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains by Fabio Cavaliere, Loic Cerf, Benjamin Dehay, Paula Ramos-Gonzalez, Francesca De Giorgi, Mathieu Bourdenx, Alban Bessede, Jose A. Obeso, Carlos Matute, François Ichas, Erwan Bezard

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Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study by Amandine Crombé, Frédéric Bertolo, Lucile Vanhersecke, Jean-Philippe Guegan, Alban Bessede, Raul Perret, François Le Loarer, Vanessa Chaire, Jean-Michel Coindre, Carlo Lucchesi, Antoine Italiano

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817 DT095895, a selective EP4 receptor antagonist with monotherapy efficacy in syngeneic mouse model(s) and best-in-class properties by Anne-Laure Blayo, Laurène Deshons, Alexia Dumont, Christel Franchet, Célia Halter, Ludovic Herbin, Gaël Hommet, Stanislas Mayer, Alban Bessede, Imane Nafia, Marjorie Sidhoum, Xavier Leroy, Stéphan Schann

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophos... by Maud Toulmonde, Jean-Philippe Guegan, Mariella Spalato-Ceruso, Florent Peyraud, Michèle Kind, Lucile Vanhersecke, François Le Loarer, Raul Perret, Coralie Cantarel, Carine Bellera, Alban Bessede, Antoine Italiano

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1519 Avelumab combined with regorafenib in solid tumors with tertiary lymphoid structures: a phase 2 REGOMUNE trial cohort by Antoine Adenis, Antoine Italiano, Carine Bellera, Philippe Cassier, Alban Bessede, Rastilav Bahleda, Jean-Philippe Metges, Sophie Cousin, Jean-Philippe Guégan, Coralie Cantarel, Michèle Kind, Jean Palussiere, Lucile Vanhersecke

Pembrolizumab combined with low-dose cyclophosphamide and intra-tumoral injection of the toll-like receptor 4 agonist G100 in patients with advanced pretreated soft tissue sarcoma:... by Mariella Spalato-Ceruso, Fanny Bouteiller, Jean-Philippe Guegan, Maud Toulmonde, Alban Bessede, Michèle Kind, Sophie Cousin, Xavier Buy, Jean Palussiere, François Le Loarer, Berengere Dadone-Montaudie, Marina Pulido, Antoine Italiano

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Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study by Cheng-Ming Sun, Maud Toulmonde, Mariella Spalato-Ceruso, Florent Peyraud, Alban Bessede, Michèle Kind, Sophie Cousin, Xavier Buy, Jean Palussiere, Antoine Bougouin, Catherine Sautès-Fridman, Hervé Wolf Fridman, Marina Pulido, Antoine Italiano

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IDO Targeting in Sarcoma: Biological and Clinical Implications by Imane Nafia, Maud Toulmonde, Doriane Bortolotto, Assia Chaibi, Dominique Bodet, Christophe Rey, Valerie Velasco, Claire B. Larmonier, Loïc Cerf, Julien Adam, François Le Loarer, Ariel Savina, Alban Bessede, Antoine Italiano, Antoine Italiano

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1521 Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer: a joint analysis of the REGOMUNE and RE... by Kohei Shitara, Antoine Adenis, Antoine Hollebecque, Antoine Italiano, Shohei Koyama, Hiroyoshi Nishikawa, Carlos Gomez-Roca, Philippe Cassier, Alban Bessede, Jean-Philippe Metges, Sophie Cousin, Jean-Philippe Guégan, Shota Fukuoka, Lola-Jade Palmieri

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma by Sébastien Corre, Nina Tardif, Nicolas Mouchet, Héloïse M. Leclair, Lise Boussemart, Arthur Gautron, Laura Bachelot, Anthony Perrot, Anatoly Soshilov, Aljosja Rogiers, Florian Rambow, Erwan Dumontet, Karin Tarte, Alban Bessede, Gilles J. Guillemin, Jean-Christophe Marine, Michael S. Denison, David Gilot, Marie-Dominique Galibert

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CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells by Abdul S. Qadir, Jean Philippe Guégan, Christophe Ginestier, Assia Chaibi, Alban Bessede, Emmanuelle Charafe-Jauffret, Manon Macario, Vincent Lavoué, Thibault de la Motte Rouge, Calvin Law, Jacob Vilker, Hongbin Wang, Emily Stroup, Matthew J. Schipma, Bryan Bridgeman, Andrea E. Murmann, Zhe Ji, Patrick Legembre, Marcus E. Peter

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