Mandibular ameloblastoma reconstruction: a case report with 10-year follow-up by Julio Alberto Villanueva-Maffei, Matías Dallaserra-Albertini, Stefan Domancic-Alucema, Gabriel Zamorano-Young, Sebastián Zapata-Baeza

Get full text

The Blockade of Tumoral IL1β-Mediated Signaling in Normal Colonic Fibroblasts Sensitizes Tumor Cells to Chemotherapy and Prevents Inflammatory CAF Activation by Natalia Guillén Díaz-Maroto, Gemma Garcia-Vicién, Giovanna Polcaro, María Bañuls, Nerea Albert, Alberto Villanueva, David G. Molleví

Get full text

Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans by Carmen Martínez-Fernández, Milana Bergamino, Alfonso Schiavi, David Brena, Natascia Ventura, Sebastian Honnen, Alberto Villanueva, Ernest Nadal, Julián Cerón

Get full text

Gene Expression Profiling as a Potential Tool for Precision Oncology in Non-Small Cell Lung Cancer by Sara Hijazo-Pechero, Ania Alay, Raúl Marín, Noelia Vilariño, Cristina Muñoz-Pinedo, Alberto Villanueva, David Santamaría, Ernest Nadal, Xavier Solé

Get full text

Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses by Helena Mazuelas, Itziar Uriarte-Arrazola, Juana Fernández-Rodríguez, Miriam Magallón-Lorenz, Alberto Villanueva, Conxi Lázaro, Bernat Gel, Eduard Serra, Meritxell Carrió

Get full text

MEK and MCL-1 sequential inhibition synergize to enhance rhabdomyosarcoma treatment by Clara Alcon, Fernando Martín, Estela Prada, Jaume Mora, Aroa Soriano, Gabriela Guillén, Soledad Gallego, Josep Roma, Josep Samitier, Alberto Villanueva, Joan Montero

Get full text

RSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machinery. by Laura Fontrodona, Montserrat Porta-de-la-Riva, Tomás Morán, Wei Niu, Mònica Díaz, David Aristizábal-Corrales, Alberto Villanueva, Simó Schwartz, Valerie Reinke, Julián Cerón

Get full text

Hepatic Carcinoma—Associated Fibroblasts Promote an Adaptative Response in Colorectal Cancer Cells That Inhibit Proliferation and Apoptosis: Nonresistant Cells Die by Nonapoptotic... by Mireia Berdiel-Acer, Monika E. Bohem, Adriana López-Doriga, August Vidal, Ramon Salazar, Maria Martínez-Iniesta, Cristina Santos, Xavier Sanjuan, Alberto Villanueva, David G. Molleví

Get full text

Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin by Francisco Javier García-Rodríguez, Carmen Martínez-Fernández, David Brena, Dmytro Kukhtar, Xènia Serrat, Ernest Nadal, Mike Boxem, Sebastian Honnen, Antonio Miranda-Vizuete, Alberto Villanueva, Julián Cerón

Get full text

1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model by Kayleigh Slater, Kayleigh Slater, Rosa Bosch, Kaelin Francis Smith, Kaelin Francis Smith, Chowdhury Arif Jahangir, Chowdhury Arif Jahangir, Sandra Garcia-Mulero, Sandra Garcia-Mulero, Arman Rahman, Arman Rahman, Fiona O’Connell, Josep M. Piulats, Valerie O’Neill, Noel Horgan, Sarah E. Coupland, Jacintha O’Sullivan, William M. Gallagher, William M. Gallagher, Alberto Villanueva, Alberto Villanueva, Breandán N. Kennedy, Breandán N. Kennedy

Get full text

Correction: Characterization of a Natural Mutator Variant of Human DNA Polymerase λ which Promotes Chromosomal Instability by Compromising NHEJ. by Gloria Terrados, Jean-Pascal Capp, Yvan Canitrot, Miguel García-Díaz, Katarzyna Bebenek, Tomas Kirchhoff, Alberto Villanueva, François Boudsocq, Valérie Bergoglio, Christophe Cazaux, Thomas A. Kunkel, Jean-Sébastien Hoffmann, Luis Blanco

Get full text

Zebrafish patient-derived xenograft models predict lymph node involvement and treatment outcome in non-small cell lung cancer by Zaheer Ali, Malin Vildevall, Gabriela Vazquez Rodriguez, Decky Tandiono, Ioannis Vamvakaris, Georgios Evangelou, Georgios Lolas, Konstantinos N. Syrigos, Alberto Villanueva, Michael Wick, Shenga Omar, Anna Erkstam, Julia Schueler, Anna Fahlgren, Lasse D. Jensen

Get full text

Patient-Derived Xenograft Models for Endometrial Cancer Research by Cristian P. Moiola, Carlos Lopez-Gil, Silvia Cabrera, Angel Garcia, Tom Van Nyen, Daniela Annibali, Tina Fonnes, August Vidal, Alberto Villanueva, Xavier Matias-Guiu, Camilla Krakstad, Frédéric Amant, Antonio Gil-Moreno, Eva Colas

Get full text

A Truncated Form of IKKα Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer by Pol Margalef, Vanessa Fernández-Majada, Alberto Villanueva, Ricard Garcia-Carbonell, Mar Iglesias, Laura López, María Martínez-Iniesta, Jordi Villà-Freixa, Mari Carmen Mulero, Montserrat Andreu, Ferran Torres, Marty W. Mayo, Anna Bigas, Lluis Espinosa

Get full text

Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer by Laia Coll-SanMartin, Veronica Davalos, David Piñeyro, Margalida Rosselló-Tortella, Alberto Bueno-Costa, Fernando Setien, Alberto Villanueva, Isabel Granada, Neus Ruiz-Xiviller, Annika Kotter, Mark Helm, Jun Yokota, Reika Kawabata-Iwakawa, Takashi Kohno, Manel Esteller

Get full text

1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature by Valentina Tonelotto, Marcel Costa-Garcia, Eve O’Reilly, Kaelin Francis Smith, Kayleigh Slater, Eugene T. Dillon, Marzia Pendino, Catherine Higgins, Paola Sist, Rosa Bosch, Sabina Passamonti, Josep M. Piulats, Alberto Villanueva, Federica Tramer, Luca Vanella, Michelle Carey, Breandán N. Kennedy

Get full text

Extramedullary multiple myeloma patient-derived orthotopic xenograft with a highly altered genome: combined molecular and therapeutic studies by Lourdes Farre, Gabriela Sanz, Neus Ruiz-Xivillé, Manuel Castro de Moura, Juan Francisco Martin-Tejera, Samuel Gonçalves-Ribeiro, Maria Martinez-Iniesta, Monica Calaf, Jose Luis Mosquera, José Ignacio Martín-Subero, Isabel Granada, Manel Esteller, Eva Domingo-Domenech, Fina Climent, Alberto Villanueva, Anna Sureda

Get full text

CDK6 is activated by the atypical cyclin I to promote E2F‐mediated gene expression and cancer cell proliferation by Eva Quandt, Núria Masip, Sara Hernández‐Ortega, Abril Sánchez‐Botet, Laura Gasa, Ainhoa Fernández‐Elorduy, Sara Plutta, Joan Marc Martínez‐Láinez, Samuel Bru, Pau M. Munoz‐Torres, Martin Floor, Jordi Villà‐Freixa, May C. Morris, August Vidal, Alberto Villanueva, Josep Clotet, Mariana P. C. Ribeiro

Get full text

Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities by Edgar Creus‐Bachiller, Juana Fernández‐Rodríguez, Miriam Magallón‐Lorenz, Sara Ortega‐Bertran, Susana Navas‐Rutete, Cleofe Romagosa, Tulio M. Silva, Maria Pané, Anna Estival, Diana Perez Sidelnikova, Mireia Morell, Helena Mazuelas, Meritxell Carrió, Tereza Lausová, David Reuss, Bernat Gel, Alberto Villanueva, Eduard Serra, Conxi Lázaro

Get full text

Oxidative stress‐induced FAK activation contributes to uterine serous carcinoma aggressiveness by Isabel C. Lopez‐Mejia, Jordi Pijuan, Raúl Navaridas, Maria Santacana, Sònia Gatius, Ana Velasco, Gerard Castellà, Anaïs Panosa, Elisa Cabiscol, Miquel Pinyol, Laura Coll, Núria Bonifaci, Laura Plata Peña, August Vidal, Alberto Villanueva, Eloi Gari, David Llobet‐Navàs, Lluis Fajas, Xavier Matias‐Guiu, Andrée Yeramian

Get full text