Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma. by Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Thierry Rème, Jennifer Torrent, Jean François Rossi, Hartmut Goldschmidt, Bernard Klein

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Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells. by Alboukadel Kassambara, Matthieu Schoenhals, Jérôme Moreaux, Jean-Luc Veyrune, Thierry Rème, Hartmut Goldschmidt, Dirk Hose, Bernard Klein

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Comparison of Immune Response Assessment in Colon Cancer by Immunoscore (Automated Digital Pathology) and Pathologist Visual Scoring by Isabelle Boquet, Alboukadel Kassambara, Alfred Lui, Alicia Tanner, Marie Latil, Yoann Lovera, Fanny Arnoux, Fabienne Hermitte, Jérôme Galon, Aurelie Catteau

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70 Deciphering the relationship between lymphocytes and macrophages within the tumor micro-environment using a workflow combining RNA transcripts detection and multiplex IHC on Bri... by Jerome Galon, Jacques Fieschi, Aurelie Collignon, Alex Trinh, Marion Olive, Maïté Chamourin, Alboukadel Kassambara, Lucie Sudre, Anthony Lebret, Giovanni Bussoti

RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma by Elina Alaterre, Veronika Vikova, Alboukadel Kassambara, Angélique Bruyer, Nicolas Robert, Guilhem Requirand, Caroline Bret, Charles Herbaux, Laure Vincent, Guillaume Cartron, Olivier Elemento, Jérôme Moreaux

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Dissecting tumor lymphocyte infiltration to predict benefit from immune-checkpoint inhibitors in metastatic colorectal cancer: lessons from the AtezoT RIBE study by Chiara Cremolini, Daniele Rossini, Sara Lonardi, Filippo Pietrantonio, Gianluca Masi, Roberto Moretto, Alessandra Boccaccino, Jerome Galon, Jacques Fieschi, Stefano Tamberi, Gabriella Fontanini, Lisa Salvatore, Clara Ugolini, Alboukadel Kassambara, Emiliano Tamburini, Veronica Conca, Aurélie Catteau, Carlotta Antoniotti, Mirella Giordano, Agnese Proietti, Anello Marcello Poma

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Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung can... by François Ghiringhelli, Frederic Bibeau, Laurent Greillier, Jean-David Fumet, Alis Ilie, Florence Monville, Caroline Laugé, Aurélie Catteau, Isabelle Boquet, Amine Majdi, Erwan Morgand, Youssef Oulkhouir, Nicolas Brandone, Julien Adam, Thomas Sbarrato, Alboukadel Kassambara, Jacques Fieschi, Stéphane Garcia, Anne Laure Lepage, Pascale Tomasini, Jérôme Galon

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460 Spatial distribution of infiltrating T lymphocytes with Immunoscore® CR T cells exhaustion test helps stratification of NSCLC patients treated with PD1/PDL1 inhibitors in the P... by Noémie Resseguier, Julien Mazières, Fabrice Barlesi, Maurice Pérol, Thomas Sbarrato, Fanny Arnoux, Stéphane Garcia, Jacques Fieschi-Meric, Vanina Leca, Alboukadel Kassambara, Lamia Ghezali, Pernelle Outters, Christelle Cotteaux-Lautard, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Luc Odier, Stéphane Hominal, Laurent Greillier

782-C Regulatory T-cell tumor infiltration is associated to better outcome in advanced NSCLC patients under ≥2nd line anti-PD1/L1 monotherapy in the PIONeeR project by Lilian Laborde, Julien Mazières, Fabrice Barlesi, Jacques Fieschi, Maurice Pérol, Vanina Leca, Alboukadel Kassambara, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Stéphane Hominal, Laurent Greillier, Marcellin Landri, Margot Vasseur, Chafik Hamdad, Margaux Mercadal, Laurent Vanhille, Sebastien Benzekry, Stephanie Martinez, Patrice Ray, Lionel Falchero, Antoine Serre, Nicolas Cloarec, Ahmed Frikha, Pierre Bory