A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery - the FOCCUS study by Cuthbertson, B, Campbell, M, Stott, SA, Elders, A, Hernández, R, Boyers, D, Norrie, J, Kinsella, J, Brittenden, J, Cook, J, Rae, D, Cotton, S, Alcorn, D, Addison, J, Grant, A