Engagement of major histocompatibility complex class I and class II molecules up-regulates intercellular adhesion of human B cells via a CD11/CD18-independent mechanism. by Alcover, A, Juillard, V, Acuto, O

The tyrosine kinase activity of p56lck is increased in human T cells activated via CD2. by Danielian, S, Fagard, R, Alcover, A, Acuto, O, Fischer, S

Lysine 271 in the transmembrane domain of the T-cell antigen receptor beta chain is necessary for its assembly with the CD3 complex but not for alpha/beta dimerization. by Alcover, A, Mariuzza, R, Ermonval, M, Acuto, O

The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2. by Danielian, S, Fagard, R, Alcover, A, Acuto, O, Fischer, S

Evidence for an extended structure of the T-cell co-receptor CD8 alpha as deduced from the hydrodynamic properties of soluble forms of the extracellular region. by Boursier, J, Alcover, A, Herve, F, Laisney, I, Acuto, O

CD3Ti+ human thymocyte-derived clones displaying a differential response to activation via CD3Ti and CD2. by Testi, R, Alcover, A, Spagnoli, G, Reinherz, E, Acuto, O

Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck. by Danielian, S, Alcover, A, Polissard, L, Stefanescu, M, Acuto, O, Fischer, S, Fagard, R

A soluble form of the human CD8 alpha chain expressed in the baculovirus system: biochemical characterization and binding to MHC class I. by Alcover, A, Hervé, F, Boursier, J, Spagnoli, G, Olive, D, Mariuzza, R, Acuto, O

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. by Michel, F, Mangino, G, Attal-Bonnefoy, G, Tuosto, L, Alcover, A, Roumier, A, Olive, D, Acuto, O

Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes. by Alcover, A, Alberini, C, Acuto, O, Clayton, L, Transy, C, Spagnoli, G, Moingeon, P, Lopez, P, Reinherz, E

The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation. by Roumier, A, Olivo-Marin, J, Arpin, M, Michel, F, Martin, M, Mangeat, P, Acuto, O, Dautry-Varsat, A, Alcover, A