Dissecting the biological heterogeneity of HER2-positive breast cancer by Francesco Schettini, Aleix Prat

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Case Report: A Case Study Documenting the Activity of Atezolizumab in a PD-L1-Negative Triple-Negative Breast Cancer by Fara Brasó-Maristany, Fara Brasó-Maristany, Miriam Sansó, Miriam Sansó, Nuria Chic, Nuria Chic, Débora Martínez, Débora Martínez, Blanca González-Farré, Blanca González-Farré, Esther Sanfeliu, Esther Sanfeliu, Lucio Ghiglione, Esther Carcelero, Javier Garcia-Corbacho, Javier Garcia-Corbacho, Marcelo Sánchez, Dolors Soy, Pedro Jares, Vicente Peg, Cristina Saura, Cristina Saura, Cristina Saura, Montserrat Muñoz, Montserrat Muñoz, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Ana Vivancos

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A perspective on the development and lack of interchangeability of the breast cancer intrinsic subtypes by Francesco Schettini, Fara Brasó-Maristany, Nicole M. Kuderer, Aleix Prat

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Interaction of host immunity with HER2-targeted treatment and tumor heterogeneity in HER2-positive breast cancer by Gaia Griguolo, Tomás Pascual, Maria Vittoria Dieci, Valentina Guarneri, Aleix Prat

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Intrinsic subtypes and therapeutic decision-making in hormone receptor-positive/HER2-negative metastatic breast cancer with visceral crisis: A case report by Francesco Schettini, Francesco Schettini, Francesco Schettini, Elia Seguí, Elia Seguí, Benedetta Conte, Esther Sanfeliu, Esther Sanfeliu, Esther Sanfeliu, Blanca Gonzalez-Farre, Blanca Gonzalez-Farre, Pedro Jares, Pedro Jares, Sergi Vidal-Sicart, Sergi Ganau, Isaac Cebrecos, Isaac Cebrecos, Fara Brasó-Maristany, Montserrat Muñoz, Montserrat Muñoz, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Maria Vidal, Maria Vidal, Maria Vidal, Maria Vidal

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First Nationwide Molecular Screening Program in Spain for Patients With Advanced Breast Cancer: Results From the AGATA SOLTI-1301 Study by Sonia Pernas, Sonia Pernas, Patricia Villagrasa, Ana Vivancos, Maurizio Scaltriti, Jordi Rodón, Jordi Rodón, Octavio Burgués, Paolo Nuciforo, Jordi Canes, Laia Paré, Marta Dueñas, Marta Dueñas, Maria Vidal, Maria Vidal, Maria Vidal, Juan Miguel Cejalvo, Juan Miguel Cejalvo, Juan Miguel Cejalvo, Antonia Perelló, Antonio Llommbard-Cussac, Joan Dorca, Alvaro Montaño, Tomás Pascual, Mafalda Oliveira, Mafalda Oliveira, Gloria Ribas, Gloria Ribas, Inmaculada Rapado, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Eva Ciruelos, Eva Ciruelos

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Unlocking the potential of engineered immune cell therapy for solid tumors by Víctor Albarrán-Fernández, Laura Angelats, Julio Delgado, Alena Gros, Álvaro Urbano-Ispizua, Sònia Guedan, Aleix Prat

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Cell Plasticity-Related Phenotypes and Taxanes Resistance in Castration-Resistant Prostate Cancer by Natalia Jiménez, Natalia Jiménez, Òscar Reig, Òscar Reig, Òscar Reig, Ruth Montalbo, Ruth Montalbo, Maria Milà-Guasch, Lluis Nadal-Dieste, Lluis Nadal-Dieste, Giancarlo Castellano, Juan José Lozano, Iván Victoria, Iván Victoria, Iván Victoria, Albert Font, Alejo Rodriguez-Vida, Joan Carles, Cristina Suárez, Montserrat Domènech, Núria Sala-González, Pedro Luis Fernández, Leonardo Rodríguez-Carunchio, Sherley Díaz, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat, Mercedes Marín-Aguilera, Mercedes Marín-Aguilera, Mercedes Marín-Aguilera, Begoña Mellado, Begoña Mellado, Begoña Mellado, Begoña Mellado

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PROCURE European consensus on breast cancer multigene signatures in early breast cancer management by Giuseppe Curigliano, Fatima Cardoso, Michael Gnant, Nadia Harbeck, Judy King, Anne-Vibeke Laenkholm, Frédérique Penault-Llorca, Aleix Prat

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Modelling hypersensitivity to trastuzumab defines biomarkers of response in HER2 positive breast cancer by Laura Díaz-Gil, Fara Brasó-Maristany, Claudriana Locatelli, Ariana Centa, Balász Győrffy, Alberto Ocaña, Aleix Prat, Atanasio Pandiella

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The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment by Adam Skibinski, Jerrica L. Breindel, Aleix Prat, Patricia Galván, Elizabeth Smith, Andreas Rolfs, Piyush B. Gupta, Joshua LaBaer, Charlotte Kuperwasser

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“Positioning of tucatinib in the new clinical scenario of HER2-positive metastatic breast cancer: An Italian and Spanish consensus paper” by Pierfranco Conte, Eva Ciruelos, Giuseppe Curigliano, Michelino De Laurentiis, Lucia Del Mastro, Alessandra Gennari, Antonio Llombart, Miguel Martìn, Francesca Poggio, Aleix Prat, Fabio Puglisi, Cristina Saura

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Neoadjuvant nivolumab + palbociclib + anastrozole for oestrogen receptor-positive/human epidermal growth factor receptor 2-negative primary breast cancer: Results from CheckMate 7A... by Guy Jerusalem, Aleix Prat, Roberto Salgado, Mattea Reinisch, Cristina Saura, Manuel Ruiz-Borrego, Petros Nikolinakos, Felipe Ades, Jeiry Filian, Ning Huang, Antonella Mazzei-Abba, Sara M. Tolaney

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Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation by Sarah Phillips, Aleix Prat, Maja Sedic, Theresa Proia, Ania Wronski, Sohini Mazumdar, Adam Skibinski, Stephanie H. Shirley, Charles M. Perou, Grace Gill, Piyush B. Gupta, Charlotte Kuperwasser

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Tumor biomarkers and efficacy in patients treated with trastuzumab emtansine + pertuzumab versus standard of care in HER2-positive early breast cancer: an open-label, phase III stu... by Sanne L. de Haas, Dennis J. Slamon, Miguel Martin, Michael F. Press, Gail D. Lewis, Chiara Lambertini, Aleix Prat, Vanesa Lopez-Valverde, Thomas Boulet, Sara A. Hurvitz

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SOLTI-1805 TOT-HER3 Study Concept: A Window-of-Opportunity Trial of Patritumab Deruxtecan, a HER3 Directed Antibody Drug Conjugate, in Patients With Early Breast Cancer by Tomás Pascual, Tomás Pascual, Tomás Pascual, Mafalda Oliveira, Mafalda Oliveira, Mafalda Oliveira, Eva Ciruelos, Eva Ciruelos, Meritxell Bellet Ezquerra, Meritxell Bellet Ezquerra, Meritxell Bellet Ezquerra, Cristina Saura, Cristina Saura, Cristina Saura, Joaquin Gavilá, Joaquin Gavilá, Sonia Pernas, Sonia Pernas, Montserrat Muñoz, Montserrat Muñoz, Montserrat Muñoz, Maria J. Vidal, Maria J. Vidal, Maria J. Vidal, Mireia Margelí Vila, Mireia Margelí Vila, Juan M. Cejalvo, Juan M. Cejalvo, Blanca González-Farré, Blanca González-Farré, Blanca González-Farré, Martin Espinosa-Bravo, Josefina Cruz, Francisco Javier Salvador-Bofill, Juan Antonio Guerra, Ana María Luna Barrera, Miriam Arumi de Dios, Stephen Esker, Pang-Dian Fan, Olga Martínez-Sáez, Guillermo Villacampa, Guillermo Villacampa, Laia Paré, Juan M. Ferrero-Cafiero, Patricia Villagrasa, Aleix Prat, Aleix Prat, Aleix Prat, Aleix Prat

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Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna® by Richard Buus, Zsolt Szijgyarto, Eugene F. Schuster, Hui Xiao, Ben P. Haynes, Ivana Sestak, Jack Cuzick, Laia Paré, Elia Seguí, Nuria Chic, Aleix Prat, Mitch Dowsett, Maggie Chon U. Cheang

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Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer by Gaia Griguolo, Maria Vittoria Dieci, Laia Paré, Federica Miglietta, Daniele Giulio Generali, Antonio Frassoldati, Luigi Cavanna, Giancarlo Bisagni, Federico Piacentini, Enrico Tagliafico, Katia Cagossi, Guido Ficarra, Aleix Prat, Pierfranco Conte, Valentina Guarneri

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582 Analysis of the HR+/HER2- breast cancer tumor microenvironment following immune priming with pelareorep and atezolizumab using imaging mass cytometry – Results from the AWARE-1... by Kevin Kelly, Matt Coffey, Tomás Pascual, Aleix Prat, Luis Manso, Thomas Heineman, Fernando Salvador, Joaquín Gavilá, Houra Loghmani, Richard Trauger, Akil Merchant, Julian Olea, Homa Dadrastoussi, Eduardo Fernandez Hernandez, Hugo Lara Martinez, Kaijin Wu

Neoadjuvant sunitinib plus exemestane in post-menopausal women with hormone receptor-positive/HER2-negative early-stage breast cancer (SUT_EXE-08): a phase I/II trial by Bartomeu Fullana, Serafín Morales, Anna Petit, Ania Alay, Helena Verdaguer, Fina Climent, Valentí Navarro-Perez, Mónica Cejuela, Patricia Galvan, Anna Gumà, Antonio Llombart-Cussac, David Cordero, Oriol Casanovas, Aleix Prat, Miguel Gil-Gil, Sonia Pernas

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