Diagnostic and Therapeutic Challenges in the Management of Intermediate and Frail Elderly Multiple Myeloma Patients by Francesca Bonello, Mario Boccadoro, Alessandra Larocca

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Clinical Applications and Future Directions of Minimal Residual Disease Testing in Multiple Myeloma by Stefania Oliva, Mattia D'Agostino, Mario Boccadoro, Alessandra Larocca

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New Strategies for the Treatment of Older Myeloma Patients by Alessandra Larocca, Lorenzo Cani, Giuseppe Bertuglia, Benedetto Bruno, Sara Bringhen

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Moving Toward Continuous Therapy in Multiple Myeloma by Francesca Bonello, Giusy Cetani, Luca Bertamini, Francesca Gay, Alessandra Larocca

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Normalization of the Immunological Microenvironment and Sustained Minimal Residual Disease Negativity: Do We Need Both for Long-Term Control of Multiple Myeloma? by Giuseppe Bertuglia, Lorenzo Cani, Alessandra Larocca, Francesca Gay, Mattia D’Agostino

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Immune dysfunctions affecting bone marrow Vγ9Vδ2 T cells in multiple myeloma: Role of immune checkpoints and disease status by Claudia Giannotta, Barbara Castella, Barbara Castella, Ezio Tripoli, Ezio Tripoli, Daniele Grimaldi, Ilaria Avonto, Mattia D’Agostino, Alessandra Larocca, Joanna Kopecka, Mariella Grasso, Chiara Riganti, Massimo Massaia, Massimo Massaia

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The prevalence and outcomes of frail older adults in clinical trials in multiple myeloma: A systematic review by Hira Mian, Arleigh McCurdy, Smith Giri, Shakira Grant, Bram Rochwerg, Erica Winks, Ashley E. Rosko, Monika Engelhardt, Charlotte Pawlyn, Gordon Cook, Graham Jackson, Sara Bringhen, Thierry Facon, Alessandra Larocca, Sonja Zweegman, Tanya M. Wildes

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Management of patients with multiple myeloma beyond the clinical-trial setting: understanding the balance between efficacy, safety and tolerability, and quality of life by Evangelos Terpos, Joseph Mikhael, Roman Hajek, Ajai Chari, Sonja Zweegman, Hans C. Lee, María-Victoria Mateos, Alessandra Larocca, Karthik Ramasamy, Martin Kaiser, Gordon Cook, Katja C. Weisel, Caitlin L. Costello, Jennifer Elliott, Antonio Palumbo, Saad Z. Usmani

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Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma by Cecilia Bandini, Elisabetta Mereu, Tina Paradzik, Maria Labrador, Monica Maccagno, Michela Cumerlato, Federico Oreglia, Lorenzo Prever, Veronica Manicardi, Elisa Taiana, Domenica Ronchetti, Mattia D’Agostino, Francesca Gay, Alessandra Larocca, Lenka Besse, Giorgio Roberto Merlo, Emilio Hirsch, Alessia Ciarrocchi, Giorgio Inghirami, Antonino Neri, Roberto Piva

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Octogenarian newly diagnosed multiple myeloma patients without geriatric impairments: the role of age >80 in the IMWG frailty score by Mattia D’Agostino, Alessandra Larocca, Massimo Offidani, Anna Marina Liberati, Gianluca Gaidano, Maria Teresa Petrucci, Daniele Derudas, Andrea Capra, Renato Zambello, Nicola Cascavilla, Paolo de Fabritiis, Vanessa Innao, Francesca Bonello, Francesca Patriarca, Giulia Benevolo, Nicola Giuliani, Gabriele Aitoro, Tommasina Guglielmelli, Francesco Di Raimondo, Paolo Corradini, Pellegrino Musto, Roman Hájek, Pieter Sonneveld, Mario Boccadoro, Sara Bringhen

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P1680: HEALTH-RELATED QUALITY OF LIFE IN TRANSPLANT-INELIGIBLE REAL-LIFE MULTIPLE MYELOMA PATIENTS TREATED WITH FIXED-DURATION BORTEZOMIB-MELPHALAN-PREDNISONE VS. CONTINUOUS LENALI... by Mattia D’agostino, Sara Bringhen, Nicola Giuliani, Elisabetta Antonioli, Renato Zambello, Francesco Cattel, Roberto Ria, Alessandro Allegra, Giovanna Leonardi, Angelo Belotti, Piero Galieni, Gloria Margiotta-Casaluci, Maria Cantonetti, Valentina Cotugno, Barbara Gamberi, Fabrizio Pane, Anna Marina Liberati, Patrizia Tosi, Maide Maria Cavalli, Donato Mannina, Giulia Benevolo, Silvia Mangiacavalli, Andrea Evangelista, Giovannino Ciccone, Mario Boccadoro, Benedetto Bruno, Alessandra Larocca

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Ixazomib-based induction regimens plus ixazomib maintenance in transplant-ineligible, newly diagnosed multiple myeloma: the phase II, multi-arm, randomized UNITO-EMN10 trial by Roberto Mina, Antonietta Pia Falcone, Sara Bringhen, Anna Marina Liberati, Norbert Pescosta, Maria Teresa Petrucci, Giovannino Ciccone, Andrea Capra, Francesca Patriarca, Delia Rota-Scalabrini, Francesca Bonello, Caterina Musolino, Michele Cea, Renato Zambello, Paola Tacchetti, Angelo Belotti, Claudia Cellini, Laura Paris, Mariella Grasso, Sara Aquino, Lorenzo De Paoli, Giovanni De Sabbata, Stelvio Ballanti, Massimo Offidani, Mario Boccadoro, Federico Monaco, Paolo Corradini, Alessandra Larocca

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Prognostic or predictive value of circulating cytokines and angiogenic factors for initial treatment of multiple myeloma in the GIMEMA MM0305 randomized controlled trial by Ilaria Saltarella, Fortunato Morabito, Nicola Giuliani, Carolina Terragna, Paola Omedè, Antonio Palumbo, Sara Bringhen, Lorenzo De Paoli, Enrica Martino, Alessandra Larocca, Massimo Offidani, Francesca Patriarca, Chiara Nozzoli, Tommasina Guglielmelli, Giulia Benevolo, Vincenzo Callea, Luca Baldini, Mariella Grasso, Giovanna Leonardi, Manuela Rizzo, Antonietta Pia Falcone, Daniela Gottardi, Vittorio Montefusco, Pellegrino Musto, Maria Teresa Petrucci, Franco Dammacco, Mario Boccadoro, Angelo Vacca, Roberto Ria

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