Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies by Alessandra Zarantonello, Henrik Pedersen, Nick S. Laursen, Gregers R. Andersen

Get full text

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System by Nick S. Laursen, Dennis V. Pedersen, Heidi Gytz, Alessandra Zarantonello, Jens Magnus Bernth Jensen, Annette G. Hansen, Steffen Thiel, Gregers R. Andersen

Get full text

Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family by Nadia Sukusu Nielsen, Alessandra Zarantonello, Seandean Lykke Harwood, Kathrine Tejlgård Jensen, Katarzyna Kjøge, Ida B. Thøgersen, Leif Schauser, Jesper Lykkegaard Karlsen, Gregers R. Andersen, Jan J. Enghild

Get full text

Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation by Alexandra Gerogianni, Alexandra Gerogianni, Jordan D. Dimitrov, Alessandra Zarantonello, Victoria Poillerat, Satheesh Chonat, Satheesh Chonat, Kerstin Sandholm, Karin E. McAdam, Kristina N. Ekdahl, Kristina N. Ekdahl, Kristina N. Ekdahl, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, Camilla Mohlin, Camilla Mohlin, Lubka T. Roumenina, Per H. Nilsson, Per H. Nilsson, Per H. Nilsson

Get full text