Alessandro Sette
Alessandro Sette is an Italian immunologist. He was born on August 11, 1960, in Rome, Italy, to Pietro Sette, a prominent Italian businessman and politician, and Renata Sette. Sette is a professor at La Jolla Institute for Immunology (LJI). He is an adjunct professor at the University of California, San Diego. Sette studies the specific epitopes that the immune system recognizes in cancer, autoimmunity, allergy, and infectious diseases.In 1988, Sette moved to San Diego to conduct research at San Diego biotech Cytel. He then co-founded Epimmune. In 2003, Sette joined the faculty of La Jolla Institute for Immunology.
Sette co-leads the Immune Epitope Database (IEDB), an NIAID-funded online database that catalogues epitopes involved in immune system recognition of allergens, infectious diseases, autoantigens, and transplanted tissue in humans and various species.
In 2020, Sette published the first study of SARS-CoV-2 epitopes targeted by the human immune system. He has co-led research into CD8+ and CD4+ T cell responses in COVID-19 patients and studied CD8+ T cell cross-reactivity to SARS-CoV-2 epitopes and other coronaviruses. Provided by Wikipedia
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The Importance of Measuring SARS-CoV-2-Specific T-Cell Responses in an Ongoing Pandemic by Linda Petrone, Alessandro Sette, Rory D. de Vries, Delia Goletti
Published 2023-06-01
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SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-1... by Alessandra Franco, Jaeyoon Song, Christina Chambers, Alessandro Sette, Alba Grifoni
Published 2023-12-01
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T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and Numerous SARS-CoV-2-Specific CD4-... by Christina D. Chambers, Jaeyoon Song, Ricardo da Silva Antunes, Alessandro Sette, Alessandra Franco
Published 2024-02-01
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Imprinting of Gut-Homing Receptors on Mtb-Specific Th1* Cells Is Associated with Reduced Lung Homing after Gavage BCG Vaccination of Rhesus Macaques by Stella G. Hoft, Keith D. Kauffman, Shunsuke Sakai, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Daniel F. Hoft, Richard Herbert, Daniel L. Barber
Published 2023-04-01
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T Cells in Multisystem Inflammatory Syndrome in Children (MIS-C) Have a Predominant CD4+ T Helper Response to SARS-CoV-2 Peptides and Numerous Virus-Specific CD4− CD8− Double-Negat... by Li-En Hsieh, Jaeyoon Song, Alba Grifoni, Chisato Shimizu, Adriana H. Tremoulet, Kirsten B. Dummer, Jane C. Burns, Alessandro Sette, Alessandra Franco
Published 2022-06-01
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Virus-Specific Stem Cell Memory CD8+ T Cells May Indicate a Long-Term Protection against Evolving SARS-CoV-2 by Milena Aleksova, Yana Todorova, Radoslava Emilova, Magdalena Baymakova, Nina Yancheva, Radina Andonova, Anelia Zasheva, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Maria Nikolova
Published 2023-03-01
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NVX-CoV2373 vaccination induces functional SARS-CoV-2–specific CD4+ and CD8+ T cell responses by Carolyn Rydyznski Moderbacher, Christina Kim, Jose Mateus, Joyce Plested, Mingzhu Zhu, Shane Cloney-Clark, Daniela Weiskopf, Alessandro Sette, Louis Fries, Gregory Glenn, Shane Crotty
Published 2022-10-01
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T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer’s disease by Jason M. Grayson, Samantha M. Short, C. Jiah Lee, Nuri Park, Caitlyn Marsac, Alessandro Sette, Cecillia S. Lindestam Arlehamn, Xiaoyan I. Leng, Samuel N. Lockhart, Suzanne Craft
Published 2023-09-01
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Combined antiviral therapy as effective and feasible option in allogenic hematopoietic stem cell transplantation during SARS-COV-2 infection: a case report by Serena Vita, Alessandra D’Abramo, Andrea Coppola, Chiara Farroni, Anna Paola Iori, Francesca Faraglia, Alessandro Sette, Alba Grifoni, Cecilia Lindestam Arlehamn, Michele Bibas, Delia Goletti, Emanuele Nicastri
Published 2024-02-01
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Characterization of the immune impairment of patients with tuberculosis and COVID-19 coinfection by Saeid Najafi-Fard, Alessandra Aiello, Assunta Navarra, Gilda Cuzzi, Valentina Vanini, Giovanni Battista Migliori, Gina Gualano, Carlotta Cerva, Alba Grifoni, Alessandro Sette, Francesco Vaia, Fabrizio Palmieri, Delia Goletti
Published 2023-05-01
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Corrigendum: Cross-reactive humoral and CD4+ T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population by Fabiola Martel, Juliana Cuervo-Rojas, Juana Ángel, Beatriz Ariza, John Mario González, Carolina Ramírez-Santana, Yeny Acosta-Ampudia, Luisa Murcia-Soriano, Norma Montoya, Claudia Cecilia Cardozo-Romero, Sandra Liliana Valderrama-Beltrán, Magda Cepeda, Julio César Castellanos, Carlos Gómez-Restrepo, Federico Perdomo-Celis, Andreu Gazquez, Alexandria Dickson, James D. Brien, José Mateus, Alba Grifoni, Alessandro Sette, Alessandro Sette, Daniela Weiskopf, Manuel A. Franco
Published 2023-08-01
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Cross-reactive humoral and CD4+ T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population by Fabiola Martel, Juliana Cuervo-Rojas, Juana Ángel, Beatriz Ariza, John Mario González, Carolina Ramírez-Santana, Yeny Acosta-Ampudia, Luisa Murcia-Soriano, Norma Montoya, Claudia Cecilia Cardozo-Romero, Sandra Liliana Valderrama-Beltrán, Magda Cepeda, Julio César Castellanos, Carlos Gómez-Restrepo, Federico Perdomo-Celis, Andreu Gazquez, Alexandria Dickson, James D. Brien, José Mateus, Alba Grifoni, Alessandro Sette, Alessandro Sette, Daniela Weiskopf, Manuel A. Franco
Published 2023-07-01
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Early and Polyantigenic CD4 T Cell Responses Correlate with Mild Disease in Acute COVID-19 Donors by Alison Tarke, Marina Potesta, Stefania Varchetta, Daniela Fenoglio, Marco Iannetta, Loredana Sarmati, Dalila Mele, Chiara Dentone, Matteo Bassetti, Carla Montesano, Mario U. Mondelli, Gilberto Filaci, Alba Grifoni, Alessandro Sette
Published 2022-06-01
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Metabolic dysregulation impairs lymphocyte function during severe SARS-CoV-2 infection by Sanjeev Gurshaney, Anamaria Morales-Alvarez, Kevin Ezhakunnel, Andrew Manalo, Thien-Huong Huynh, Jun-Ichi Abe, Nhat-Tu Le, Daniela Weiskopf, Alessandro Sette, Daniel S. Lupu, Stephen J. Gardell, Hung Nguyen
Published 2023-04-01
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Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus by Flavia Chiuppesi, John A. Zaia, Miguel-Angel Gutierrez-Franco, Sandra Ortega-Francisco, Minh Ly, Mindy Kha, Taehyun Kim, Shannon Dempsey, Swagata Kar, Alba Grifoni, Alessandro Sette, Felix Wussow, Don J. Diamond
Published 2024-02-01
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