The Promising Link Among Tumor Mutational Burden, Immune-Related Adverse Events, and Immune Checkpoint Inhibitors Efficacy in SCLC by Alessio Cortellini, MD

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The interplay between cholesterol (and other metabolic conditions) and immune-checkpoint immunotherapy: shifting the concept from the “inflamed tumor” to the “inflamed patient”... by Melissa Bersanelli, Alessio Cortellini, Sebastiano Buti

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Family history of cancer and DNA damage response genes: Two sides of the same coin? by Alessio Cortellini, Melissa Bersanelli, Corrado Ficorella, Sebastiano Buti

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Targeting KRAS in Solid Tumors: Current Challenges and Future Opportunities of Novel KRAS Inhibitors by Alice Indini, Erika Rijavec, Michele Ghidini, Alessio Cortellini, Francesco Grossi

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Effects of immune checkpoint inhibitor associated endocrinopathies on cancer survival by Lisa Yang, Sruthi Murthy, Alessio Cortellini, Alessio Cortellini, Emma A. Lim, Michael Gonzalez, David J. Pinato, David J. Pinato, Mariana Abdel-Malek, Sarah Mahmoud, Niamh M. Martin, Niamh M. Martin

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Are anti-PD1 and anti-PD-L1 alike? The non-small-cell lung cancer paradigm by Giuseppe Luigi Banna, Ornella Cantale, Melissa Bersanelli, Marzia Del Re, Alex Friedlaender, Alessio Cortellini, Alfredo Addeo

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Rare bone toxicity associated with vismodegib by Valeria Ciciarelli, MD, Alessio Cortellini, MD, Alessandra Ventura, MD, Carlota Gutiérrez García-Rodrigo, MD, Corrado Ficorella, MD, Maria Concetta Fargnoli, MD

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Immunotherapy-related adverse events in real-world patients with advanced non-small cell lung cancer on chemoimmunotherapy: a Spinnaker study sub-analysis by Shobana Anpalakhan, Prerana Huddar, Roya Behrouzi, Alessio Signori, Judith Cave, Charles Comins, Alessio Cortellini, Alessio Cortellini, Alfredo Addeo, Carles Escriu, Hayley McKenzie, Gloria Barone, Lisa Murray, David J. Pinato, David J. Pinato, Christian Ottensmeier, Sara Campos, Sethupathi Muthuramalingam, Samuel Chan, Fabio Gomes, Giuseppe L. Banna

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Predictive value of skeletal muscle mass for immunotherapy with nivolumab in non‐small cell lung cancer patients: A “hypothesis‐generator” preliminary report by Alessio Cortellini, Lucilla Verna, Giampiero Porzio, Federico Bozzetti, Pierpaolo Palumbo, Carlo Masciocchi, Katia Cannita, Alessandro Parisi, Davide Brocco, Nicola Tinari, Corrado Ficorella

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Looking for A Place for Dose-Dense TMZ Regimens in GBM Patients: An Experience with MGMT Exploratory Evaluation by Luca Napoleoni, Alessio Cortellini, Katia Cannita, Alessandro Parisi, Antonella Dal Mas, Giuseppe Calvisi, Olga Venditti, Paola Lanfiuti Baldi, Valentina Cocciolone, Alessandro Ricci, Corrado Ficorella

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Tryptophan Catabolism as Immune Mechanism of Primary Resistance to Anti-PD-1 by Andrea Botticelli, Silvia Mezi, Giulia Pomati, Bruna Cerbelli, Edoardo Cerbelli, Michela Roberto, Raffaele Giusti, Alessio Cortellini, Luana Lionetto, Simone Scagnoli, Ilaria Grazia Zizzari, Marianna Nuti, Maurizio Simmaco, Paolo Marchetti

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Immunotherapy for Metastatic Non-Small Cell Lung Cancer: Therapeutic Advances and Biomarkers by Marco Russano, Giulia La Cava, Alessio Cortellini, Fabrizio Citarella, Alessandro Galletti, Giuseppina Rita Di Fazio, Valentina Santo, Leonardo Brunetti, Alessia Vendittelli, Iacopo Fioroni, Francesco Pantano, Giuseppe Tonini, Bruno Vincenzi

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Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis by Francesco Pantano, Flavia Tramontana, Michele Iuliani, Giulia Leanza, Sonia Simonetti, Alessandra Piccoli, Annalisa Paviglianiti, Alessio Cortellini, Gian Paolo Spinelli, Umile Giuseppe Longo, Rocky Strollo, Bruno Vincenzi, Giuseppe Tonini, Nicola Napoli, Daniele Santini

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Efficacy and safety of frontline systemic therapy for advanced HCC: A network meta-analysis of landmark phase III trials by Claudia Angela Maria Fulgenzi, Bernhard Scheiner, James Korolewicz, Charalampos-Vlasios Stikas, Alessandra Gennari, Bruno Vincenzi, Mark R. Openshaw, Marianna Silletta, Matthias Pinter, Alessio Cortellini, Lorenza Scotti, Antonio D’Alessio, David J. Pinato

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32 C-reactive protein (CRP) as a prognostic biomarker in advanced non-small cell lung cancer treated with immune checkpoint inhibitors. Results from a multi-center international ob... by Abdul Rafeh Naqash, Mahvish Muzaffar, Shravanti Macherla, Alessio Cortellini, James Clark, Emma Mi, Sanna Livanainen, Daria Gramenitskaya, Kevin O’Brien, Jussi Koivunen, Sweta Jonnalagadda, Shanker Polsani, Rahim Jiwani, Nitika Sharma, Chipman Stroud, Paul Walker, David Pinato

PRIME-HCC: phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma by David J. Pinato, Alessio Cortellini, Ajithkumar Sukumaran, Tom Cole, Madhava Pai, Nagy Habib, Duncan Spalding, Mikael H. Sodergren, Maria Martinez, Tony Dhillon, Paul Tait, Robert Thomas, Caroline Ward, Hemant Kocher, Vincent Yip, Sarah Slater, Rohini Sharma

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The Effects of GCSF Primary Prophylaxis on Survival Outcomes and Toxicity in Patients with Advanced Non-Small Cell Lung Cancer on First-Line Chemoimmunotherapy: A Sub-Analysis of t... by Shobana Anpalakhan, Prerana Huddar, Roya Behrouzi, Alessio Signori, Judith Cave, Charles Comins, Alessio Cortellini, Alfredo Addeo, Carles Escriu, Hayley McKenzie, Gloria Barone, Lisa Murray, Gagan Bhatnagar, David J. Pinato, Christian Ottensmeier, Fabio Gomes, Giuseppe Luigi Banna

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The Impact of Locoregional Treatment on Response to Nivolumab in Advanced Platinum Refractory Head and Neck Cancer: The Need Trial by Andrea Botticelli, Silvia Mezi, Giulia Pomati, Paolo Sciattella, Bruna Cerbelli, Michela Roberto, Giulia Mammone, Alessio Cirillo, Alessandra Cassano, Carmela Di Dio, Alessio Cortellini, Laura Pizzuti, Graziana Ronzino, Massimiliano Salati, Patrizia Vici, Antonella Polimeni, Marco Carlo Merlano, Marianna Nuti, Paolo Marchetti

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Association between antibiotics and adverse oncological outcomes in patients receiving targeted or immune-based therapy for hepatocellular carcinoma by David J. Pinato, Xiaoxue Li, Pallavi Mishra-Kalyani, Antonio D’Alessio, Claudia A.M. Fulgenzi, Bernhard Scheiner, Matthias Pinter, Guo Wei, Julie Schneider, Donna R. Rivera, Richard Pazdur, Marc R. Theoret, Sandra Casak, Steven Lemery, Lola Fashoyin-Aje, Alessio Cortellini, Lorraine Pelosof

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The role of diabetes in metastatic melanoma patients treated with nivolumab plus relatlimab by Domenico Mallardo, Rachel Woodford, Alexander M. Menzies, Lisa Zimmer, Andrew williamson, Egle Ramelyte, Florentia Dimitriou, Alexandre Wicky, Roslyn Wallace, Mario Mallardo, Alessio Cortellini, Alfredo Budillon, Victoria Atkinson, Shahneen Sandhu, Michielin Olivier, Reinhard Dummer, Paul Lorigan, Dirk Schadendorf, Georgina V. Long, Ester Simeone, Paolo A. Ascierto

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