Theoretical Model of EphA2-Ephrin A1 Inhibition by Wiktoria Jedwabny, Alessio Lodola, Edyta Dyguda-Kazimierowicz

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Homology Models of Melatonin Receptors: Challenges and Recent Advances by Silvia Rivara, Gilberto Spadoni, Annalida Bedini, Alessio Lodola, Daniele Pala

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Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase by Andrea Ghidini, Laura Scalvini, Francesca Palese, Alessio Lodola, Marco Mor, Daniele Piomelli

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Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. by Carmine Giorgio, Iftiin Hassan Mohamed, Lisa Flammini, Elisabetta Barocelli, Matteo Incerti, Alessio Lodola, Massimiliano Tognolini

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A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations. by Alessio Lodola, Davide Branduardi, Marco De Vivo, Luigi Capoferri, Marco Mor, Daniele Piomelli, Andrea Cavalli

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Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids by Lorenzo Guidetti, Riccardo Castelli, Laura Scalvini, Francesca Ferlenghi, Miriam Corrado, Carmine Giorgio, Massimiliano Tognolini, Alessio Lodola

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Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists by Donatella Callegari, Daniele Pala, Laura Scalvini, Massimiliano Tognolini, Matteo Incerti, Silvia Rivara, Marco Mor, Alessio Lodola

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A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence by Claudio Festuccia, Miriam Corrado, Alessandra Rossetti, Riccardo Castelli, Alessio Lodola, Giovanni Luca Gravina, Massimiliano Tognolini, Carmine Giorgio

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MT2 selective melatonin receptor antagonists: design and structure-activity relationships by Silvia Rivara, Marco Mor, Simone Lorenzi, Alessio Lodola, Pier Vincenzo Plazzi Gilberto Spadoni, Annalida Bedini, Giorgio Tarzia

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Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavaila... by Francesca Ferlenghi, Carmine Giorgio, Matteo Incerti, Lorenzo Guidetti, Paola Chiodelli, Marco Rusnati, Massimiliano Tognolini, Federica Vacondio, Marco Mor, Alessio Lodola

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UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling by Carmine Giorgio, Marika Allodi, Simone Palese, Andrea Grandi, Massimiliano Tognolini, Riccardo Castelli, Alessio Lodola, Lisa Flammini, Anna Maria Cantoni, Elisabetta Barocelli, Simona Bertoni

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Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC ^min/J Mice by Miriam Corrado, Carmine Giorgio, Elisabetta Barocelli, Giuseppe Vittucci Marzetti, Anna Maria Cantoni, Rosanna Di Lecce, Matteo Incerti, Riccardo Castelli, Alessio Lodola, Massimiliano Tognolini

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Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats. by Federica Vacondio, Michele Bassi, Claudia Silva, Riccardo Castelli, Caterina Carmi, Laura Scalvini, Alessio Lodola, Valentina Vivo, Lisa Flammini, Elisabetta Barocelli, Marco Mor, Silvia Rivara

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Analysis of ADAM12-Mediated Ephrin-A1 Cleavage and Its Biological Functions by Katsuaki Ieguchi, Takeshi Tomita, Toshifumi Takao, Tsutomu Omori, Taishi Mishima, Isao Shimizu, Massimiliano Tognolini, Alessio Lodola, Takuya Tsunoda, Shinichi Kobayashi, Satoshi Wada, Yoshiro Maru

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Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells by Aurora Diotallevi, Laura Scalvini, Gloria Buffi, Yolanda Pérez-Pertejo, Mauro De Santi, Michele Verboni, Gianfranco Favi, Mauro Magnani, Alessio Lodola, Simone Lucarini, Luca Galluzzi

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Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD by Andrea Grandi, Irene Zini, Simone Palese, Carmine Giorgio, Massimiliano Tognolini, Francesco Marchesani, Stefano Bruno, Lisa Flammini, Anna Maria Cantoni, Riccardo Castelli, Alessio Lodola, Antonella Fusari, Elisabetta Barocelli, Simona Bertoni

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Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor by Alessio Lodola, Silvia Rivara, Elisabetta Barocelli, Francesca De Franco, Paola Vicini, Antimo Gioiello, Carmine Giorgio, Iftiin Hassan-Mohamed, Riccardo Castelli, Daniele Pala, Matteo Incerti, Marco Mor, Massimiliano Tognolini, Simonetta Russo

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Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell L... by Claudia Fumarola, Nicole Bozza, Riccardo Castelli, Francesca Ferlenghi, Giuseppe Marseglia, Alessio Lodola, Mara Bonelli, Silvia La Monica, Daniele Cretella, Roberta Alfieri, Roberta Minari, Maricla Galetti, Maricla Galetti, Marcello Tiseo, Marcello Tiseo, Andrea Ardizzoni, Marco Mor, Pier Giorgio Petronini

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Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models by Silvia La Monica, Federica Vacondio, Kamal Eltayeb, Alessio Lodola, Francesco Volta, Martina Viglioli, Francesca Ferlenghi, Francesca Galvani, Maricla Galetti, Mara Bonelli, Claudia Fumarola, Andrea Cavazzoni, Lisa Flammini, Michela Verzè, Roberta Minari, Pier Giorgio Petronini, Marcello Tiseo, Marco Mor, Roberta Alfieri

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Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2 by Francisco J. Medrano, Sergio de la Hoz-Rodríguez, Sergio Martí, Kemel Arafet, Tanja Schirmeister, Stefan J. Hammerschmidt, Christin Müller, Águeda González-Martínez, Elena Santillana, John Ziebuhr, Antonio Romero, Collin Zimmer, Annabelle Weldert, Robert Zimmermann, Alessio Lodola, Katarzyna Świderek, Vicent Moliner, Florenci V. González

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