Often neglected steps in transforming drug solubility from single measurement in pure water to physiologically-appropriate solubility-pH Autor Alex Avdeef

Získat plný text

Mechanistically transparent models for predicting aqueous solubility of rigid, slightly flexible, and very flexible drugs (MW<2000) Accuracy near that of random forest regression Autor Alex Avdeef

Získat plný text

Anomalous salting-out, self-association and pKa effects in the practically-insoluble bromothymol blue Autor Alex Avdeef

Získat plný text

Integration of In Silico, In Vitro and In Situ Tools for the Preformulation and Characterization of a Novel Cardio-Neuroprotective Compound during the Early Stages of Drug Developm... Autor Claudia Miranda, Alejandro Ruiz-Picazo, Paula Pomares, Isabel Gonzalez-Alvarez, Marival Bermejo, Marta Gonzalez-Alvarez, Alex Avdeef, Miguel-Ángel Cabrera-Pérez

Získat plný text

Effects of Different Weak Small Organic Acids on Clofazimine Solubility in Aqueous Media Autor Igor A. Topalović, Olivera S. Marković, Miloš P. Pešić, Mufaddal H. Kathawala, Martin Kuentz, Alex Avdeef, Abu T. M. Serajuddin, Tatjana Ž. Verbić

Získat plný text

Understanding the pH Dependence of Supersaturation State—A Case Study of Telmisartan Autor Szabina Kádár, Dóra Csicsák, Petra Tőzsér, Attila Farkas, Tamás Pálla, Arash Mirzahosseini, Blanka Tóth, Gergő Tóth, Béla Fiser, Péter Horváth, János Madarász, Alex Avdeef, Krisztina Takács-Novák, Bálint Sinkó, Enikő Borbás, Gergely Völgyi

Získat plný text