Optimising laboratory monitoring of chronic conditions in primary care: a quality improvement framework by Alex J Walker, Richard Croker, Jessica Watson, Andy Brogan, Darunee Whiting, Tom Lewis

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Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data by Ben Goldacre, Carl Reynolds, Anna Powell-Smith, Alex J Walker, Tom A Yates, Richard Croker, Liam Smeeth

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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribin... by Helen J Curtis, Brian MacKenna, Bhavana Reddy, Alex J Walker, Sebastian Bacon, Rafael Perera, Ben Goldacre

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Data-Driven Identification of Potentially Successful Intervention Implementations Using 5 Years of Opioid Prescribing Data: Retrospective Database Study by Lisa EM Hopcroft, Helen J Curtis, Richard Croker, Felix Pretis, Peter Inglesby, David Evans, Sebastian Bacon, Ben Goldacre, Alex J Walker, Brian MacKenna

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Data-Driven Identification of Unusual Prescribing Behavior: Analysis and Use of an Interactive Data Tool Using 6 Months of Primary Care Data From 6500 Practices in England by Lisa EM Hopcroft, Jon Massey, Helen J Curtis, Brian Mackenna, Richard Croker, Andrew D Brown, Thomas O'Dwyer, Orla Macdonald, David Evans, Peter Inglesby, Sebastian CJ Bacon, Ben Goldacre, Alex J Walker

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Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP by Agnieszka Lemanska, Colm Andrews, Louis Fisher, Seb Bacon, Adam E Frampton, Amir Mehrkar, Peter Inglesby, Simon Davy, Keith Roberts, Praveetha Patalay, Ben Goldacre, Brian MacKenna, The OpenSAFELY Collaborative, Alex J Walker

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Identifying Patterns of Clinical Interest in Clinicians’ Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review by Brian MacKenna, Helen J Curtis, Lisa E M Hopcroft, Alex J Walker, Richard Croker, Orla Macdonald, Stephen J W Evans, Peter Inglesby, David Evans, Jessica Morley, Sebastian C J Bacon, Ben Goldacre

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First dose COVID-19 vaccine coverage amongst adolescents and children in England: an analysis of 3.21 million patients' primary care records in situ using OpenSAFELY [version 2; pe... by Frank Hester, John Parry, Sam Harper, Colm D. Andrews, Christopher Bates, Peter Inglesby, Alex J. Walker, Lisa E. Hopcroft, Laurie A. Tomlinson, Helen J. Curtis, Sebastian C. Bacon, Andrew D. Brown, Caroline E. Morton, Viyaasan Mahalingasivam, Rosalind M. Eggo, Edward P. K. Parker, William J. Hulme, Ben Goldacre, Brian MacKenna, Jonathan Cockburn, Jessica Morley, Amir Mehrkar

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Studying the Long-term Impact of COVID-19 in Kids (SLICK). Healthcare use and costs in children and young people following community-acquired SARS-CoV-2 infection: protocol for an... by Ashley Akbari, James Farrell, Aziz Sheikh, Ben Goldacre, Alex J Walker, Ewen M Harrison, Laurie A Tomlinson, Ronan Lyons, Sinead Brophy, Jennifer Preston, Colin R Simpson, Nazir I Lone, Louisa Pollock, Annemarie B Docherty, J Kenneth Baillie, Malcolm G Semple, Peter S Hall, Olivia V Swann, Sohan Seth, Thomas C Williams, Srinivasa V Katikireddi, Michael J Seaborne, J. Samantha Ainsworth, Freya F Semple

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Factors associated with COVID-19 vaccine uptake in people with kidney disease: an OpenSAFELY cohort study by Ben Goldacre, Sam Harper, Alex J Walker, William J Hulme, Dorothea Nitsch, Laurie A Tomlinson, Bang Zheng, Helen J Curtis, Amir Mehrkar, Jonathan Cockburn, John Parry, Frank Hester, Retha Steenkamp, Elizabeth J Williamson, Shalini Santhakumaran, Jonathan AC Sterne, John Tazare, Michelle Willicombe, Fiona Loud, Viyaasan Mahalingasivam, Louis Fisher, Linda Nab, Christopher Bates, Edward PK Parker, Edward J Carr, Amelia CA Green, Elsie MF Horne, Susan Lyon

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OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic by Ben Goldacre, David Evans, Sam Harper, Alex J Walker, Richard Croker, Liam Smeeth, Rohini Mathur, Krishnan Bhaskaran, Henry Drysdale, Ian Douglas, Harriet Forbes, Elizabeth Williamson, Brian MacKenna, William Hulme, Anna Schultze, Christopher T Rentsch, Seb Bacon, Chris Bates, Helen J Curtis, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, Laurie Tomlinson, Rosalind M Eggo, John Parry, Frank Hester, Simon Davy, Angel Yun Wong, Caroline Morton, George Hickman, Tom Ward

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Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients’ records at source using OpenSAFELY by The OpenSAFELY Collaborative, Colm D. Andrews, Rohini Mathur, Jon Massey, Robin Park, Helen J. Curtis, Lisa Hopcroft, Amir Mehrkar, Seb Bacon, George Hickman, Rebecca Smith, David Evans, Tom Ward, Simon Davy, Peter Inglesby, Iain Dillingham, Steven Maude, Thomas O’Dwyer, Ben F. C. Butler-Cole, Lucy Bridges, Chris Bates, John Parry, Frank Hester, Sam Harper, Jonathan Cockburn, Ben Goldacre, Brian MacKenna, Laurie A. Tomlinson, Alex J. Walker, William J. Hulme

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Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in O... by Richard J McManus, Ben Goldacre, David Evans, Alex J Walker, Christopher Wood, Jessica Morley, Brian MacKenna, Christopher T Rentsch, Seb Bacon, Chris Bates, Helen J Curtis, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, Laurie Tomlinson, John Parry, Frank Hester, Amelia Green, Miriam Samuel, Rose Higgins, Andrew D Brown, Viyaasan Mahalingasivam, Caroline Morton, Rebecca M Smith, Louis Fisher, Lisa Hopcroft, Jon Massey, Iain Dillingham, Steven Maude, Milan Wiedemann, Colm Andrews, Christine Cunningham, Victoria Speed, Caroline Walters

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Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration dat... by Krishnan Bhaskaran, Christopher T Rentsch, George Hickman, William J Hulme, Anna Schultze, Helen J Curtis, Kevin Wing, Charlotte Warren-Gash, Laurie Tomlinson, Chris J Bates, Rohini Mathur, Brian MacKenna, Viyaasan Mahalingasivam, Angel Wong, Alex J Walker, Caroline E Morton, Daniel Grint, Amir Mehrkar, Rosalind M Eggo, Peter Inglesby, Ian J Douglas, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, John Parry, Frank Hester, Sam Harper, Stephen Jw Evans, Sebastian Bacon, Liam Smeeth, Ben Goldacre

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Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using fede... by Paul Griffiths, Ben Goldacre, David Evans, Sam Harper, Orla Macdonald, Alex J Walker, Richard Croker, Anthony J Avery, Caroline E Morton, Jessica Morley, Brian MacKenna, William Hulme, Sarah Rodgers, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, John Parry, Frank Hester, James Barrett, Amelia Green, Helen Curtis, Sebastian Bacon, Simon Davy, George Hickman, Tom Ward, Louis Fisher, Jon Massey, Iain Dillingham, Christopher Bates, Lisa EM Hopcroft, Kerry Oliver, Dai Evans, Becky Smith, Shaun O’Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Aaron Fowles, Nasreen Parkes

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Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform [version 1; peer review: 2 ap... by Richard Croker, Anna Schultze, Simon Davy, David Evans, John Parry, Angel YS. Wong, Alex J. Walker, Kevin Wing, Sam Harper, Liam Smeeth, Helen J. Curtis, Caroline E. Morton, Caroline Minassian, Helen I. McDonald, Emily Nightingale, Ian J Douglas, Ketaki Bhate, William J. Hulme, Emma Powell, Dorothea Nitsch, Frank Hester, Amy Mulick, Stephen JW. Evans, Charlotte Warren-Gash, Rosalind M. Eggo, Elizabeth J. Williamson, Krishnan Bhaskaran, John Tazare, Laurie A. Tomlinson, Chris Bates, Harriet Forbes, Peter Inglesby, Ben Goldacre, Brian MacKenna, Jonathan Cockburn, Rohini Mathur, Seb Bacon, George Hickman, Christopher T. Rentsch, Amir Mehrkar

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Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through... by Louis Fisher, Helen J Curtis, Richard Croker, Milan Wiedemann, Victoria Speed, Christopher Wood, Andrew Brown, Lisa EM Hopcroft, Rose Higgins, Jon Massey, Peter Inglesby, Caroline E Morton, Alex J Walker, Jessica Morley, Amir Mehrkar, Seb Bacon, George Hickman, Orla Macdonald, Tom Lewis, Marion Wood, Martin Myers, Miriam Samuel, Robin Conibere, Wasim Baqir, Harpreet Sood, Charles Drury, Kiren Collison, Chris Bates, David Evans, Iain Dillingham, Tom Ward, Simon Davy, Rebecca M Smith, William Hulme, Amelia Green, John Parry, Frank Hester, Sam Harper, Jonathan Cockburn, Shaun O'Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Brian MacKenna, Ben Goldacre

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Impact of vaccination on the association of COVID-19 with cardiovascular diseases: An OpenSAFELY cohort study by Genevieve I. Cezard, Rachel E. Denholm, Rochelle Knight, Yinghui Wei, Lucy Teece, Renin Toms, Harriet J. Forbes, Alex J. Walker, Louis Fisher, Jon Massey, Lisa E. M. Hopcroft, Elsie M. F. Horne, Kurt Taylor, Tom Palmer, Marwa Al Arab, Jose Ignacio Cuitun Coronado, Samantha H. Y. Ip, Simon Davy, Iain Dillingham, Sebastian Bacon, Amir Mehrkar, Caroline E. Morton, Felix Greaves, Catherine Hyams, George Davey Smith, John Macleod, Nishi Chaturvedi, Ben Goldacre, William N. Whiteley, Angela M. Wood, Jonathan A. C. Sterne, Venexia Walker, On behalf of the Longitudinal Health and Wellbeing and Data and Connectivity UK COVID-19 National Core Studies, CONVALESCENCE study and the OpenSAFELY collaborative

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Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform [version 2; peer review: 2 approved] by Richard Croker, Anna Schultze, Frank Hester, John Parry, Rafael Perera, Sam Harper, Rosalind M. Eggo, Liam Smeeth, Ewout Steyerberg, Caroline Minassian, Ruth Keogh, Karla Diaz-Ordaz, Stephen J.W. Evans, Elizabeth J. Williamson, Krishnan Bhaskaran, John Tazare, Helen I McDonald, Alex J. Walker, Sebastian Bacon, Laurie A. Tomlinson, Helen J. Curtis, Chris Bates, Caroline E. Morton, Harriet Forbes, Amir Mehrkar, Emily Nightingale, Brian D Nicholson, Richard Grieve, Dave Evans, Peter Inglesby, David Harrison, Ben Goldacre, David Leon, Jonathan Cockburn, Brian MacKenna, Rohini Mathur, Will J. Hulme, Nicholas G. Davies, Ian J. Douglas, Jessica Morley, Angel Wong, Christopher T. Rentsch

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Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descripti... by Ben Goldacre, David Evans, Sam Harper, Orla Macdonald, Alex J Walker, Richard Croker, William J Hulme, Colm D Andrews, Laurie A Tomlinson, Krishnan Bhaskaran, Henry Drysdale, Nicholas J DeVito, Ian J Douglas, Caroline E Morton, Jessica Morley, Bang Zheng, Brian MacKenna, Stephen J W Evans, Christopher T Rentsch, Helen J Curtis, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, John Parry, Frank Hester, Rose Higgins, Simon Davy, John Tazare, Viyaasan Mahalingasivam, George Hickman, Tom Ward, Rebecca M Smith, Amelia C A Green, Louis Fisher, Sebastian C J Bacon, Robin Y Park, Jon Massey, Iain Dillingham, Linda Nab, Christopher Bates, Lisa E M Hopcroft, Milan Wiedemann

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