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scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria od Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

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Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm od Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Daniel Ssozi, Daniel Ssozi, Marina Ainciburu, Jonathan Good, Jonathan Good, Jenny Noel, Jenny Noel, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Charles P. Couturier, Charles P. Couturier, Charles P. Couturier, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Sary F. Aranki, Hari R. Mallidi, Gabriel K. Griffin, Gabriel K. Griffin, Gabriel K. Griffin, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Peter van Galen, Peter van Galen, Peter van Galen, Peter van Galen

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Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response od Hylton E. Rodel, Hylton E. Rodel, Isabella A. T. M. Ferreira, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Yashica Ganga, Mallory Bernstein, Shi-Hsia Hwa, Shi-Hsia Hwa, Kievershen Nargan, Gila Lustig, Gilla Kaplan, Mahdad Noursadeghi, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Adrie J. C. Steyn, Adrie J. C. Steyn, Adrie J. C. Steyn, Alex Sigal, Alex Sigal, Alex Sigal, Alex Sigal

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Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets od Emily Berger, Deniz Yorukoglu, Lillian Zhang, Sarah K. Nyquist, Alex K. Shalek, Manolis Kellis, Ibrahim Numanagić, Bonnie Berger

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Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip od Amir Bein, Seongmin Kim, Girija Goyal, Wuji Cao, Cicely Fadel, Arash Naziripour, Sanjay Sharma, Ben Swenor, Nina LoGrande, Atiq Nurani, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Andrew W. Navia, Andrew W. Navia, Andrew W. Navia, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, Carly G. K. Ziegler, José Ordovas Montañes, José Ordovas Montañes, José Ordovas Montañes, Pranav Prabhala, Min Sun Kim, Rachelle Prantil-Baun, Melissa Rodas, Amanda Jiang, Lucy O’Sullivan, Gladness Tillya, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Donald E. Ingber, Donald E. Ingber, Donald E. Ingber

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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity od Dania Zhivaki, Francesco Borriello, Ohn A. Chow, Benjamin Doran, Ira Fleming, Derek J. Theisen, Paris Pallis, Alex K. Shalek, Caroline L. Sokol, Ivan Zanoni, Jonathan C. Kagan

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Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection od Aaron J. Wilk, Joshua O. Marceau, Samuel W. Kazer, Ira Fleming, Vincent N. Miao, Jennyfer Galvez-Reyes, Jason T. Kimata, Alex K. Shalek, Susan Holmes, Julie Overbaugh, Catherine A. Blish

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Functional compensation precedes recovery of tissue mass following acute liver injury od Chad M. Walesky, Kellie E. Kolb, Carolyn L. Winston, Jake Henderson, Benjamin Kruft, Ira Fleming, Sungjin Ko, Satdarshan P. Monga, Florian Mueller, Udayan Apte, Alex K. Shalek, Wolfram Goessling

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Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration od Madhvi Menon, Shahin Mohammadi, Jose Davila-Velderrain, Brittany A. Goods, Tanina D. Cadwell, Yu Xing, Anat Stemmer-Rachamimov, Alex K. Shalek, John Christopher Love, Manolis Kellis, Brian P. Hafler

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Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses od Florian Douam, Carly G. K. Ziegler, Gabriela Hrebikova, Bruno Fant, Robert Leach, Lance Parsons, Wei Wang, Jenna M. Gaska, Benjamin Y. Winer, Brigitte Heller, Alex K. Shalek, Alexander Ploss

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HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control od Rabiah Fardoos, Rabiah Fardoos, Sarah K. Nyquist, Sarah K. Nyquist, Osaretin E. Asowata, Samuel W. Kazer, Alveera Singh, Abigail Ngoepe, Jennifer Giandhari, Ntombifuthi Mthabela, Dirhona Ramjit, Samita Singh, Farina Karim, Søren Buus, Frank Anderson, J. Zachary Porterfield, J. Zachary Porterfield, J. Zachary Porterfield, J. Zachary Porterfield, Andile L. Sibiya, Rishan Bipath, Kumeshan Moodley, Warren Kuhn, Warren Kuhn, Bonnie Berger, Son Nguyen, Tulio de Oliveira, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Philip Goulder, Philip Goulder, Philip Goulder, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alasdair Leslie, Alasdair Leslie, Henrik N. Kløverpris, Henrik N. Kløverpris, Henrik N. Kløverpris

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Linking single-cell measurements of mass, growth rate, and gene expression od Robert J. Kimmerling, Sanjay M. Prakadan, Alejandro J. Gupta, Nicholas L. Calistri, Mark M. Stevens, Selim Olcum, Nathan Cermak, Riley S. Drake, Kristine Pelton, Frederik De Smet, Keith L. Ligon, Alex K. Shalek, Scott R. Manalis

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