1060 Optimally engineered IL18 Fc-fusion proteins balance potency and pharmacokinetics to promote strong anti-tumor activity by Christine Bonzon, Rumana Rashid, Irene Leung, Nicole Rodriguez, Alex Nisthal, Ruschelle Love, Sung-Hyung Lee, Panida Lertkiatmongkol, Sher Karki, Kendra N Avery, Norman J Barlow, Seung Y Chu, Gregory L Moore, John R Desjarlais