Strongly Truncated Dnaaf4 Plays a Conserved Role in Drosophila Ciliary Dynein Assembly as Part of an R2TP-Like Co-Chaperone Complex With Dnaaf6 by Jennifer Lennon, Petra zur Lage, Alex von Kriegsheim, Andrew P. Jarman

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H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci [version 4; peer review: 2 approved... by Jayakumar Sundarraj, Gillian C.A. Taylor, Alex von Kriegsheim, Madapura M Pradeepa

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Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib by Aoife Nolan, Cinzia Raso, Walter Kolch, Alex von Kriegsheim, Kieran Wynne, David Matallanas

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Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols by Stefan Schildknecht, Alex von Kriegsheim, Ksenija Vujacic-Mirski, Fabio Di Lisa, Volker Ullrich, Andreas Daiber

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Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities by Milad Ghomlaghi, Mandy Theocharous, Nhan Hoang, Sung-Young Shin, Alex von Kriegsheim, Eric O’ Neill, Tao Zhang, Lan K. Nguyen

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The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly by Petra zur Lage, Zhiyan Xi, Jennifer Lennon, Iain Hunter, Wai Kit Chan, Alfonso Bolado Carrancio, Alex von Kriegsheim, Andrew P. Jarman

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Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons by Lewis Macdonald, Gillian C Taylor, Jennifer Margaret Brisbane, Ersi Christodoulou, Lucy Scott, Alex von Kriegsheim, Janet Rossant, Bin Gu, Andrew J Wood

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Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways by Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

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Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration by Alfonso Bolado-Carrancio, Oleksii S Rukhlenko, Elena Nikonova, Mikhail A Tsyganov, Anne Wheeler, Amaya Garcia-Munoz, Walter Kolch, Alex von Kriegsheim, Boris N Kholodenko

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A Novel C1q Domain-Containing Protein Isolated from the Mollusk <i>Modiolus kurilensis</i> Recognizing Glycans Enriched with Acidic Galactans and Mannans by Andrei V. Grinchenko, Alex von Kriegsheim, Nikita A. Shved, Anna E. Egorova, Diana V. Ilyaskina, Tatiana D. Karp, Nikolay V. Goncharov, Irina Y. Petrova, Vadim V. Kumeiko

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Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE by Miguel Cavadas, Ioanna Oikonomidi, Catarina J. Gaspar, Emma Burbridge, Marina Badenes, Inês Félix, Alfonso Bolado, Tianyi Hu, Andrea Bileck, Christopher Gerner, Pedro M. Domingos, Alex von Kriegsheim, Colin Adrain

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Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function by Fiona Haward, Magdalena M Maslon, Patricia L Yeyati, Nicolas Bellora, Jan N Hansen, Stuart Aitken, Jennifer Lawson, Alex von Kriegsheim, Dagmar Wachten, Pleasantine Mill, Ian R Adams, Javier F Caceres

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Correction: A novel role of MNT as a negative regulator of REL and the NF-κB pathway by Judit Liaño-Pons, M. Carmen Lafita-Navarro, Lorena García-Gaipo, Carlota Colomer, Javier Rodríguez, Alex von Kriegsheim, Peter J. Hurlin, Fabiana Ourique, M. Dolores Delgado, Anna Bigas, Lluis Espinosa, Javier León

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A novel role of MNT as a negative regulator of REL and the NF-κB pathway by Judit Liaño-Pons, M. Carmen Lafita-Navarro, Lorena García-Gaipo, Carlota Colomer, Javier Rodríguez, Alex von Kriegsheim, Peter J. Hurlin, Fabiana Ourique, M. Dolores Delgado, Anna Bigas, M. Lluis Espinosa, Javier León

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An Integrated Global Analysis of Compartmentalized HRAS Signaling by Tapesh Santra, Ana Herrero, Javier Rodriguez, Alex von Kriegsheim, Luis F. Iglesias-Martinez, Thomas Schwarzl, Des Higgins, Thin-Thin Aye, Albert J.R. Heck, Fernando Calvo, Lorena Agudo-Ibáñez, Piero Crespo, David Matallanas, Walter Kolch

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Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism by Dylan Gerard Ryan, Ming Yang, Hiran A Prag, Giovanny Rodriguez Blanco, Efterpi Nikitopoulou, Marc Segarra-Mondejar, Christopher A Powell, Tim Young, Nils Burger, Jan Lj Miljkovic, Michal Minczuk, Michael P Murphy, Alex von Kriegsheim, Christian Frezza

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iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE by Ioanna Oikonomidi, Emma Burbridge, Miguel Cavadas, Graeme Sullivan, Blanka Collis, Heike Naegele, Danielle Clancy, Jana Brezinova, Tianyi Hu, Andrea Bileck, Christopher Gerner, Alfonso Bolado, Alex von Kriegsheim, Seamus J Martin, Florian Steinberg, Kvido Strisovsky, Colin Adrain

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Characterisation of a nucleo-adhesome by Adam Byron, Billie G. C. Griffith, Ana Herrero, Alexander E. P. Loftus, Emma S. Koeleman, Linda Kogerman, John C. Dawson, Niamh McGivern, Jayne Culley, Graeme R. Grimes, Bryan Serrels, Alex von Kriegsheim, Valerie G. Brunton, Margaret C. Frame

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Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice by Jonas Eckrich, Katie Frenis, Giovanny Rodriguez-Blanco, Yue Ruan, Subao Jiang, Maria Teresa Bayo Jimenez, Marin Kuntic, Matthias Oelze, Omar Hahad, Huige Li, Adrian Gericke, Sebastian Steven, Sebastian Strieth, Alex von Kriegsheim, Thomas Münzel, Benjamin Philipp Ernst, Andreas Daiber

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Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer by Helen F. Titmarsh, Helen F. Titmarsh, Alex von Kriegsheim, Jimi C. Wills, Richard A. O’Connor, Kevin Dhaliwal, Margaret C. Frame, Samuel B. Pattle, David A. Dorward, David A. Dorward, Adam Byron, Adam Byron, Ahsan R. Akram, Ahsan R. Akram

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