L‐BAIBA Synergizes with Sub‐Optimal Mechanical Loading to Promote New Bone Formation nork Matt Prideaux, Alberto Smargiassi, Gang Peng, Marco Brotto, Alexander G Robling, Lynda F Bonewald

Testu osoa

Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth. nork Noah J Mathis, Emily N Adaniya, Lauren M Smith, Alexander G Robling, Karl J Jepsen, Stephen H Schlecht

Testu osoa

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting nork Roy B Choi, Whitney A Bullock, April M Hoggatt, Gabriela G Loots, Damian C Genetos, Alexander G Robling

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The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells nork Karl J Lewis, Xin Yi, Christian S Wright, Emily Z Pemberton, Whitney A Bullock, William R Thompson, Alexander G Robling

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Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo nork Whitney A. Bullock, April M. Hoggatt, Daniel J. Horan, Andrew J. Elmendorf, Amy Y. Sato, Teresita Bellido, Gabriela G. Loots, Fredrick M. Pavalko, Alexander G. Robling

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The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. nork Xiaohua Wu, Shi Chen, Yongzheng He, Steven D Rhodes, Khalid S Mohammad, Xiaohong Li, Xianlin Yang, Li Jiang, Grzegorz Nalepa, Paige Snider, Alexander G Robling, D Wade Clapp, Simon J Conway, Theresa A Guise, Feng-Chun Yang

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Control of bone mass and remodeling by PTH receptor signaling in osteocytes. nork Charles A O'Brien, Lilian I Plotkin, Carlo Galli, Joseph J Goellner, Arancha R Gortazar, Matthew R Allen, Alexander G Robling, Mary Bouxsein, Ernestina Schipani, Charles H Turner, Robert L Jilka, Robert S Weinstein, Stavros C Manolagas, Teresita Bellido

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Independent validation of experimental results requires timely and unrestricted access to animal models and reagents. nork Cassandra R Diegel, Steven Hann, Ugur M Ayturk, Jennifer C W Hu, Kyung-Eun Lim, Casey J Droscha, Zachary B Madaj, Gabrielle E Foxa, Isaac Izaguirre, VAI Vivarium and Transgenics Core, Alexander G Robling, Matthew L Warman, Bart O Williams

Testu osoa

An osteocalcin-deficient mouse strain without endocrine abnormalities. nork Cassandra R Diegel, Steven Hann, Ugur M Ayturk, Jennifer C W Hu, Kyung-Eun Lim, Casey J Droscha, Zachary B Madaj, Gabrielle E Foxa, Isaac Izaguirre, Vai Vivarium And Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L Dowd, Alexander G Robling, Matthew L Warman, Bart O Williams

Testu osoa

Gabapentin Disrupts Binding of Perlecan to the α₂δ₁ Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation nork Perla C. Reyes Fernandez, Christian S. Wright, Adrianna N. Masterson, Xin Yi, Tristen V. Tellman, Andrei Bonteanu, Katie Rust, Megan L. Noonan, Kenneth E. White, Karl J. Lewis, Uma Sankar, Julia M. Hum, Gregory Bix, Danielle Wu, Alexander G. Robling, Rajesh Sardar, Mary C. Farach-Carson, William R. Thompson

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Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth. nork Aina He, Songhai Tian, Oded Kopper, Daniel J Horan, Peng Chen, Roderick T Bronson, Ren Sheng, Hao Wu, Lufei Sui, Kun Zhou, Liang Tao, Quan Wu, Yujing Huang, Zan Shen, Sen Han, Xueqing Chen, Hong Chen, Xi He, Alexander G Robling, Rongsheng Jin, Hans Clevers, Dongxi Xiang, Zhe Li, Min Dong

Testu osoa

Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease nork Rafiou Agoro, Intawat Nookaew, Megan L. Noonan, Yamil G. Marambio, Sheng Liu, Wennan Chang, Wennan Chang, Hongyu Gao, Hongyu Gao, Lainey M. Hibbard, Corinne E. Metzger, Daniel Horan, William R. Thompson, Xiaoling Xuei, Yunlong Liu, Yunlong Liu, Chi Zhang, Chi Zhang, Alexander G. Robling, Lynda F. Bonewald, Lynda F. Bonewald, Jun Wan, Kenneth E. White, Kenneth E. White

Testu osoa