Revisiting the MMTV Zoonotic Hypothesis to Account for Geographic Variation in Breast Cancer Incidence nork Alexandre F. R. Stewart, Hsiao-Huei Chen

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Activation of tyrosine phosphatases in the progression of Alzheimer's disease nork Alexandre F. R. Stewart, Hsiao-Huei Chen

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Interferon regulatory factor 2 binding protein 2: a new player of the innate immune response for stroke recovery nork Hsiao-Huei Chen, Alexandre F. R. Stewart

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N-methyl-D-aspartate receptor functions altered by neuronal PTP1B activation in Alzheimer’s disease and schizophrenia models nork Alexandre F R. Stewart, Hsiao-Huei Chen

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Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury nork Shelly A Cruz, Zhaohong Qin, Alexandre F. R. Stewart, Hsiao-Huei Chen

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Ketamine's schizophrenia-like effects are prevented by targeting PTP1B nork Zhaohong Qin, Li Zhang, Michael A. Zasloff, Alexandre F.R. Stewart, Hsiao-Huei Chen

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Neuronal protein-tyrosine phosphatase 1B hinders sensory-motor functional recovery and causes affective disorders in two different focal ischemic stroke models nork Shelly A Cruz, Zhaohong Qin, Konrad M Ricke, Alexandre F.R. Stewart, Hsiao-Huei Chen

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Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors nork Li Zhang, Zhaohong Qin, Konrad M. Ricke, Shelly A. Cruz, Alexandre F. R. Stewart, Hsiao-Huei Chen

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Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice nork Ragnar O. Vilmundarson, Ragnar O. Vilmundarson, Ragnar O. Vilmundarson, Niloufar Heydarikhorneh, Niloufar Heydarikhorneh, Niloufar Heydarikhorneh, An Duong, An Duong, An Duong, Tiffany Ho, Tiffany Ho, Tiffany Ho, Kianoosh Keyhanian, Kianoosh Keyhanian, Kianoosh Keyhanian, Kianoosh Keyhanian, Fariborz Soheili, Fariborz Soheili, Fariborz Soheili, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Alexandre F. R. Stewart, Alexandre F. R. Stewart, Alexandre F. R. Stewart

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Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease nork Li Zhang, Zhaohong Qin, Fariba Sharmin, Wei Lin, Konrad M. Ricke, Michael A. Zasloff, Alexandre F.R. Stewart, Hsiao-Huei Chen

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Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2. nork Allen C T Teng, Naif A M Al-Montashiri, Brian L M Cheng, Philip Lou, Pinar Ozmizrak, Hsiao-Huei Chen, Alexandre F R Stewart

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Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury nork Shelly A. Cruz, Shelly A. Cruz, Shelly A. Cruz, Aswin Hari, Aswin Hari, Aswin Hari, Zhaohong Qin, Zhaohong Qin, Pascal Couture, Pascal Couture, Pascal Couture, Hua Huang, Hua Huang, Hua Huang, Diane C. Lagace, Diane C. Lagace, Diane C. Lagace, Alexandre F. R. Stewart, Alexandre F. R. Stewart, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen

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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease nork Jaana A. Hartiala, W. H. Wilson Tang, Zeneng Wang, Amanda L. Crow, Alexandre F. R. Stewart, Robert Roberts, Ruth McPherson, Jeanette Erdmann, Christina Willenborg, Stanley L. Hazen, Hooman Allayee

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SPG7 Variant Escapes Phosphorylation-Regulated Processing by AFG3L2, Elevates Mitochondrial ROS, and Is Associated with Multiple Clinical Phenotypes nork Naif A.M. Almontashiri, Hsiao-Huei Chen, Ryan J. Mailloux, Takashi Tatsuta, Allen C.T. Teng, Ahmad B. Mahmoud, Tiffany Ho, Nicolas A.S. Stewart, Peter Rippstein, Mary Ellen Harper, Robert Roberts, Christina Willenborg, Jeanette Erdmann, Annalisa Pastore, Heidi M. McBride, Thomas Langer, Alexandre F.R. Stewart

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Correction: Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease. nork Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F. R. Stewart, Cornelius Boerkoel, Stephen W. Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger

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Rare copy number variants contribute to congenital left-sided heart disease. nork Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F R Stewart, Cornelius Boerkoel, Stephen W Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger

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Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. nork Ville-Petteri Mäkinen, Mete Civelek, Qingying Meng, Bin Zhang, Jun Zhu, Candace Levian, Tianxiao Huan, Ayellet V Segrè, Sujoy Ghosh, Juan Vivar, Majid Nikpay, Alexandre F R Stewart, Christopher P Nelson, Christina Willenborg, Jeanette Erdmann, Stefan Blakenberg, Christopher J O'Donnell, Winfried März, Reijo Laaksonen, Stephen E Epstein, Sekar Kathiresan, Svati H Shah, Stanley L Hazen, Muredach P Reilly, Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium, Aldons J Lusis, Nilesh J Samani, Heribert Schunkert, Thomas Quertermous, Ruth McPherson, Xia Yang, Themistocles L Assimes

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Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease. nork Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz

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Correction: Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease. nork Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz

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A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. nork J Brent Richards, Dawn Waterworth, Stephen O'Rahilly, Marie-France Hivert, Ruth J F Loos, John R B Perry, Toshiko Tanaka, Nicholas John Timpson, Robert K Semple, Nicole Soranzo, Kijoung Song, Nuno Rocha, Elin Grundberg, Josée Dupuis, Jose C Florez, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Robert Sladek, Yurii Aulchenko, David Evans, Gerard Waeber, Jeanette Erdmann, Mary-Susan Burnett, Naveed Sattar, Joseph Devaney, Christina Willenborg, Aroon Hingorani, Jaquelin C M Witteman, Peter Vollenweider, Beate Glaser, Christian Hengstenberg, Luigi Ferrucci, David Melzer, Klaus Stark, John Deanfield, Janina Winogradow, Martina Grassl, Alistair S Hall, Josephine M Egan, John R Thompson, Sally L Ricketts, Inke R König, Wibke Reinhard, Scott Grundy, H-Erich Wichmann, Phil Barter, Robert Mahley, Y Antero Kesaniemi, Daniel J Rader, Muredach P Reilly, Stephen E Epstein, Alexandre F R Stewart, Cornelia M Van Duijn, Heribert Schunkert, Keith Burling, Panos Deloukas, Tomi Pastinen, Nilesh J Samani, Ruth McPherson, George Davey Smith, Timothy M Frayling, Nicholas J Wareham, James B Meigs, Vincent Mooser, Tim D Spector, GIANT Consortium

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