Membrane Interactions and Toxicity by Misfolded Protein Oligomers by Mario Gonzalez-Garcia, Giuliana Fusco, Alfonso De Simone, Alfonso De Simone

Get full text

Metal interactions of α-synuclein probed by NMR amide-proton exchange by Mario Gonzalez-Garcia, Giuliana Fusco, Alfonso De Simone, Alfonso De Simone

Get full text

Plasticity of Membrane Binding by the Central Region of α-Synuclein by Carlos Navarro-Paya, Maximo Sanz-Hernandez, Alfonso De Simone, Alfonso De Simone

Get full text

Editorial: Oligomers in amyloid-associated diseases—structural properties and toxicity by Neville Vassallo, Neville Vassallo, Sandrine Ongeri, Alfonso De Simone, Alfonso De Simone

Get full text

The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes by Giuliana Fusco, Francesco Bemporad, Fabrizio Chiti, Christopher M. Dobson, Alfonso De Simone, Alfonso De Simone

Get full text

Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins by Nicole Balasco, Luciana Esposito, Alfonso De Simone, Luigi Vitagliano

Get full text

Multi-scale simulations provide supporting evidence for the hypothesis of intramolecular protein translocation in GroEL/GroES complexes. by Ivan Coluzza, Alfonso De Simone, Franca Fraternali, Daan Frenkel

Get full text

In Silico Study of the Mechanism of Binding of the N-Terminal Region of α Synuclein to Synaptic-Like Membranes by Carlos Navarro-Paya, Maximo Sanz-Hernandez, Alfonso De Simone

Get full text

Thermal tuning of protein hydration in a hyperthermophilic enzyme by Giuliana Fusco, Carmen Biancaniello, Michail D. Vrettas, Alfonso De Simone

Get full text

Structure of a low-population intermediate state in the release of an enzyme product by Alfonso De Simone, Francesco A Aprile, Anne Dhulesia, Christopher M Dobson, Michele Vendruscolo

Get full text

Demonstration of Binding Induced Structural Plasticity in a SH2 Domain by Lorenzo Visconti, Angelo Toto, James A. Jarvis, Francesca Troilo, Francesca Malagrinò, Alfonso De Simone, Stefano Gianni

Get full text

Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy. by Nadia Tinto, Adriana Zagari, Marina Capuano, Alfonso De Simone, Valentina Capobianco, Gerardo Daniele, Michela Giugliano, Raffaella Spadaro, Adriana Franzese, Lucia Sacchetti

Get full text

Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation by Daniel K Weber, U Venkateswara Reddy, Songlin Wang, Erik K Larsen, Tata Gopinath, Martin B Gustavsson, Razvan L Cornea, David D Thomas, Alfonso De Simone, Gianluigi Veglia

Get full text

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity by Amberley D. Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco, Neeleema Seetaloo, Anass Chiki, Philippa J. Woodhams, Ioanna Mela, Hilal A. Lashuel, Jonathan J. Phillips, Alfonso De Simone, Frank Sobott, Gabriele S. Kaminski Schierle

Get full text

Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers by Laura Boi, Augusta Pisanu, Maria Francesca Palmas, Giuliana Fusco, Ezio Carboni, Maria Antonietta Casu, Valentina Satta, Maria Scherma, Elzbieta Janda, Ignazia Mocci, Giovanna Mulas, Anna Ena, Saturnino Spiga, Paola Fadda, Alfonso De Simone, Anna R. Carta

Get full text

The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior... by Maria Francesca Palmas, Michela Etzi, Augusta Pisanu, Chiara Camoglio, Claudia Sagheddu, Michele Santoni, Maria Francesca Manchinu, Mauro Pala, Giuliana Fusco, Alfonso De Simone, Luca Picci, Giovanna Mulas, Saturnino Spiga, Maria Scherma, Paola Fadda, Marco Pistis, Nicola Simola, Ezio Carboni, Anna R. Carta

Get full text

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction by Janin Lautenschläger, Amberley D. Stephens, Giuliana Fusco, Florian Ströhl, Nathan Curry, Maria Zacharopoulou, Claire H. Michel, Romain Laine, Nadezhda Nespovitaya, Marcus Fantham, Dorothea Pinotsi, Wagner Zago, Paul Fraser, Anurag Tandon, Peter St George-Hyslop, Eric Rees, Jonathan J. Phillips, Alfonso De Simone, Clemens F. Kaminski, Gabriele S. Kaminski Schierle

Get full text