Alison Goate

Alison Mary Goate is the Jean C. and James W. Crystal Professor and Chair of the Department of Genetics and Genomic Sciences and Director of the Loeb Center for Alzheimer's Disease at Icahn School of Medicine at Mount Sinai, New York City. She was previously professor of genetics in psychiatry, professor of genetics, and professor of neurology at Washington University School of Medicine.

The Goate Lab studies the genetics and molecular bases of Alzheimer's disease, frontotemporal dementia, and alcoholism. Provided by Wikipedia
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  1. 1
    Autosomal Dominant Alzheimer’s Disease Mutations in Human Microglia Are Not Sufficient to Trigger Amyloid Pathology in WT Mice but Might Affect Pathology in 5XFAD Mice

    Autosomal Dominant Alzheimer’s Disease Mutations in Human Microglia Are Not Sufficient to Trigger Amyloid Pathology in WT Mice but Might Affect Pathology in 5XFAD Mice by Carmen Romero-Molina, Sarah M. Neuner, Marcelina Ryszawiec, Alice Pébay, Dominantly Inherited Alzheimer Network, Edoardo Marcora, Alison Goate

    Published 2024-02-01
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  2. 2
    APOE3 AND APOE4 HIPSC-DERIVED ASTROCYTES DIFFERENTIALLY CONTRIBUTE TO ALZHEIMER’S PATHOLOGY IN CHIMERIC MICE

    APOE3 AND APOE4 HIPSC-DERIVED ASTROCYTES DIFFERENTIALLY CONTRIBUTE TO ALZHEIMER’S PATHOLOGY IN CHIMERIC MICE by Joan Cruz-Sesé, María Alfonso-Triguero, Jon Olano-Bringas, Leire Ruiz, Nuria Galbis, Pranav Preman, An Snellinx, Julia Tcw, Elena Alberdi, Alison Goate, Bart De Strooper, Amaia Mendiguren Arranz

    Published 2023-10-01
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  3. 3
    P430: Application of ACMG/AMP variant classification guidelines to Alzheimer’s disease-associated genetic variation

    P430: Application of ACMG/AMP variant classification guidelines to Alzheimer’s disease-associated genetic variation by Alexa Dickson, Meagan Corliss, Jonathan Heusel, Ellen Ziegemeier, Jorge Llibre-Guerra, Alison Goate, Carlos Cruchaga, Alan Renton, Celeste Karch, Victoria Fernandez Hernandez, Gregory Day, Laura Courtney, Eric McDade, Randall Bateman, Kevin Bowling

    Published 2023-01-01
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  4. 4
    Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models

    Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models by James A. Gregory, Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern, Natalie Barretto, Nadine Schrode, Güney Akbalik, Kristy Kang, Esther Cheng, Kathryn Bowles, Steven Lotz, Susan Goderie, Celeste M. Karch, Sally Temple, Alison Goate, Kristen J. Brennand, Hemali Phatnani

    Published 2020-06-01
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  5. 5
    Sex specific molecular networks and key drivers of Alzheimer’s disease

    Sex specific molecular networks and key drivers of Alzheimer’s disease by Lei Guo, Jiqing Cao, Jianwei Hou, Yonghe Li, Min Huang, Li Zhu, Larry Zhang, Yeji Lee, Mariana Lemos Duarte, Xianxiao Zhou, Minghui Wang, Chia-Chen Liu, Yuka Martens, Michael Chao, Alison Goate, Guojun Bu, Vahram Haroutunian, Dongming Cai, Bin Zhang

    Published 2023-06-01
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  6. 6
    Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease

    Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease by Diane Xue, William S. Bush, Alan E. Renton, Edoardo A. Marcora, Joshua C. Bis, Brian W. Kunkle, The Alzheimer's Disease Sequencing Project, Eric Boerwinkle, Anita L. DeStefano, Lindsay Farrer, Alison Goate, Richard Mayeux, Margaret Pericak‐Vance, Gerard Schellenberg, Sudha Seshadri, Ellen Wijsman, Jonathan L. Haines, Elizabeth E. Blue

    Published 2021-01-01
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  7. 7
    Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease

    Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease by Min Qiao, Annie J. Lee, Dolly Reyes‐Dumeyer, Giuseppe Tosto, Kelley Faber, Alison Goate, Alan Renton, Michael Chao, Brad Boeve, Carlos Cruchaga, Margaret Pericak‐Vance, Jonathan L. Haines, Roger Rosenberg, Debby Tsuang, Robert A. Sweet, David A. Bennett, Robert S. Wilson, Tatiana Foroud, Richard Mayeux, Badri N. Vardarajan

    Published 2023-05-01
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  8. 8
    New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop

    New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop by Maria A. Telpoukhovskaia, Thomas J. Murdy, Olivia J. Marola, Kevin Charland, Michael MacLean, Tain Luquez, Alexandra M. Lish, Sarah Neuner, Amy Dunn, Kristen D. Onos, Jesse Wiley, Derek Archer, Matthew J. Huentelman, Matthias Arnold, Vilas Menon, Alison Goate, Linda J. Van Eldik, Paul R. Territo, Gareth R. Howell, Gregory W. Carter, Kristen M. S. O'Connell, Catherine C. Kaczorowski, the 2022 JAX CADR Workshop

    Published 2024-01-01
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  9. 9
    Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

    Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease by Lihua Wang, Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li, Zhaohua Wang, Muhammad Ali, Chengran Yang, Menghan Liu, William Brock, Marta Marquié, Mercè Boada, Ignacio Alvarez, Miquel Aguilar, Pau Pastor, Agustín Ruiz, Raquel Puerta, Adelina Orellana, Jarod Rutledge, Hamilton Oh, Michael D Greicius, Yann Le Guen, Richard J. Perrin, Tony Wyss-Coray, Angela Jefferson, Timothy J. Hohman, Neill Graff-Radford, Hiroshi Mori, Alison Goate, Johannes Levin, Yun Ju Sung, Carlos Cruchaga

    Published 2024-01-01
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  10. 10
    COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder

    COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder by Jacquelyn L. Meyers, Vivia V. McCutcheon, Kristina A. Horne-Osipenko, Lawrence R. Waters, Peter Barr, Grace Chan, David B. Chorlian, Emma C. Johnson, Sally I-Chun Kuo, John R. Kramer, Danielle M. Dick, Samuel Kuperman, Chella Kamarajan, Gayathri Pandey, Dzov Singman, Stacey Subbie-Saenz de Viteri, Jessica E. Salvatore, Laura J. Bierut, Tatiana Foroud, Alison Goate, Victor Hesselbrock, John Nurnberger, Martin H. Plaweck, Marc A. Schuckit, Arpana Agrawal, Howard J. Edenberg, Kathleen K. Bucholz, Bernice Porjesz

    Published 2023-10-01
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  11. 11
    Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease

    Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease by Muhammad Ali, Derek B. Archer, Priyanka Gorijala, Daniel Western, Jigyasha Timsina, Maria V. Fernández, Ting-Chen Wang, Claudia L. Satizabal, Qiong Yang, Alexa S. Beiser, Ruiqi Wang, Gengsheng Chen, Brian Gordon, Tammie L. S. Benzinger, Chengjie Xiong, John C. Morris, Randall J. Bateman, Celeste M. Karch, Eric McDade, Alison Goate, Sudha Seshadri, Richard P. Mayeux, Reisa A. Sperling, Rachel F. Buckley, Keith A. Johnson, Hong-Hee Won, Sang-Hyuk Jung, Hang-Rai Kim, Sang Won Seo, Hee Jin Kim, Elizabeth Mormino, Simon M. Laws, Kang-Hsien Fan, M. Ilyas Kamboh, Prashanthi Vemuri, Vijay K. Ramanan, Hyun-Sik Yang, Allen Wenzel, Hema Sekhar Reddy Rajula, Aniket Mishra, Carole Dufouil, Stephanie Debette, Oscar L. Lopez, Steven T. DeKosky, Feifei Tao, Michael W. Nagle, Knight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), Alzheimer’s Disease Neuroimaging Initiative (ADNI), ADNI-DOD, A4 Study Team, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, Timothy J. Hohman, Yun Ju Sung, Logan Dumitrescu, Carlos Cruchaga

    Published 2023-04-01
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