Targeted therapeutic mild hypercapnia after cardiac arrest by Glenn M. Eastwood, Alistair Nichol, Matt P. Wise

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Clinician-researcher's perspectives on clinical research during the COVID19 pandemic. by Sarah L Silverberg, Lisa M Puchalski Ritchie, Nina Gobat, Alistair Nichol, Srinivas Murthy

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Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysis by David McConnell, Marie Harte, Cathal Walsh, Desmond Murphy, Alistair Nichol, Michael Barry, Roisin Adams

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In‐Depth Extracorporeal Cardiopulmonary Resuscitation in Adult Out‐of‐Hospital Cardiac Arrest by Mark Dennis, Sean Lal, Paul Forrest, Alistair Nichol, Lionel Lamhaut, Richard J. Totaro, Brian Burns, Claudio Sandroni

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Advancing preparedness for clinical research during infectious disease epidemics by Nina Gobat, John Amuasi, Yazdan Yazdanpanah, Louise Sigfid, Hugh Davies, John-Paul Byrne, Gail Carson, Christopher Butler, Alistair Nichol, Herman Goossens

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The NAPRESSIM trial: the use of low-dose, prophylactic naloxone infusion to prevent respiratory depression with intrathecally administered morphine in elective hepatobiliary surger... by David Cosgrave, Marie Galligan, Era Soukhin, Victoria McMullan, Siobhan McGuinness, Anand Puttappa, Niamh Conlon, John Boylan, Rabia Hussain, Peter Doran, Alistair Nichol

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Preparing accessible and understandable clinical research participant information leaflets and consent forms: a set of guidelines from an expert consensus conference by Eleanor Coleman, Lydia O’Sullivan, Rachel Crowley, Moira Hanbidge, Seán Driver, Thilo Kroll, Aoife Kelly, Alistair Nichol, Orlaith McCarthy, Prasanth Sukumar, Peter Doran

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Development of the Consumer Involvement & Engagement Toolkit: a digital resource to build capacity for undertaking patient-centred clinical trials in Australia by Tanya Symons, Janelle Bowden, Anne McKenzie, Julia M Fallon-Ferguson, Leanne Y Weekes, James Ansell, Rinki Murphy, Shilpa Jesudason, Manoj Saxena, Alistair Nichol, Nicola Straiton

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Correction: Prophylaxis in healthcare workers during a pandemic: a model for a multi-centre international randomised controlled trial using Bayesian analyses by Pepa Bruce, Kate Ainscough, Lee Hatter, Irene Braithwaite, Lindsay R. Berry, Mark Fitzgerald, Thomas Hills, Kathy Brickell, David Cosgrave, Alex Semprini, Susan Morpeth, Scott Berry, Peter Doran, Paul Young, Richard Beasley, Alistair Nichol

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Prophylaxis in healthcare workers during a pandemic: a model for a multi-centre international randomised controlled trial using Bayesian analyses by Pepa Bruce Metadata, Kate Ainscough, Lee Hatter, Irene Braithwaite, Lindsay R. Berry, Mark Fitzgerald, Thomas Hills, Kathy Brickell, David Cosgrave, Alex Semprini, Susan Morpeth, Scott Berry, Peter Doran, Paul Young, Richard Beasley, Alistair Nichol

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Correction: Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups—practical guidance to support better practice by Shoba Dawson, Katie Banister, Katie Biggs, Seonaidh Cotton, Declan Devane, Heidi Gardner, Katie Gillies, Gosala Gopalakrishnan, Talia Isaacs, Kamlesh Khunti, Alistair Nichol, Adwoa Parker, Amy M. Russell, Victoria Shepherd, Frances Shiely, Gillian Shorter, Bella Starling, Hywel Williams, Andrew Willis, Miles D. Witham, Shaun Treweek

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Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups—practical guidance to support better practice by Shoba Dawson, Katie Banister, Katie Biggs, Seonaidh Cotton, Declane Devane, Heidi Gardner, Katie Gillies, Gosala Gopalakrishnan, Talia Isaacs, Kamlesh Khunti, Alistair Nichol, Adwoa Parker, Amy M. Russell, Victoria Shepherd, Frances Shiely, Gillian Shorter, Bella Starling, Hywel Williams, Andrew Willis, Miles D. Witham, Shaun Treweek

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Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC-WHO clinical characterisation protocol. by Marina Wainstein, Samual MacDonald, Daniel Fryer, Kyle Young, Valeria Balan, Husna Begum, Aidan Burrell, Barbara Wanjiru Citarella, J Perren Cobb, Sadie Kelly, Kalynn Kennon, James Lee, Laura Merson, Srinivas Murthy, Alistair Nichol, Malcolm G Semple, Samantha Strudwick, Steven A Webb, Patrick Rossignol, Rolando Claure-Del Granado, Sally Shrapnel, ISARIC Clinical Characterisation Group

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Statistical analysis plan for the POLAR-RCT: The Prophylactic hypOthermia trial to Lessen trAumatic bRain injury-Randomised Controlled Trial by Jeffrey Presneill, Dashiell Gantner, Alistair Nichol, Colin McArthur, Andrew Forbes, Jessica Kasza, Tony Trapani, Lynnette Murray, Stephen Bernard, Peter Cameron, Gilles Capellier, Olivier Huet, Lynette Newby, Stephen Rashford, Jeffrey V. Rosenfeld, Tony Smith, Michael Stephenson, Dinesh Varma, Shirley Vallance, Tony Walker, Steve Webb, D. James Cooper, On behalf of the POLAR investigators and the ANZICS Clinical Trials Group

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Biomarkers of brain injury after cardiac arrest; a statistical analysis plan from the TTM2 trial biobank investigators by Marion Moseby-Knappe, Helena Levin, Kaj Blennow, Susann Ullén, Henrik Zetterberg, Gisela Lilja, Josef Dankiewicz, Janus Christian Jakobsen, Alice Lagebrant, Hans Friberg, Alistair Nichol, Kate Ainschough, Glenn M. Eastwood, Matt P. Wise, Matthew Thomas, Thomas Keeble, Alain Cariou, Christoph Leithner, Christian Rylander, Joachim Düring, Jan Bělohlávek, Anders Grejs, Ola Borgquist, Johan Undén, Maryline Simon, Vinzent Rolny, Alex Piehler, Tobias Cronberg, Niklas Nielsen

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Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest: a statistical analysis plan by Janus Christian Jakobsen, Josef Dankiewicz, Theis Lange, Tobias Cronberg, Gisela Lilja, Helena Levin, Jan Bělohlávek, Clifton Callaway, Alain Cariou, David Erlinge, Jan Hovdenes, Michael Joannidis, Per Nordberg, Mauro Oddo, Paolo Pelosi, Hans Kirkegaard, Glenn Eastwood, Christian Rylander, Manoj Saxena, Christian Storm, Fabio Silvio Taccone, Matthew P. Wise, Matt P. G. Morgan, Paul Young, Alistair Nichol, Hans Friberg, Susann Ullén, Niklas Nielsen

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Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital C... by Chiara Robba, Rafael Badenes, Denise Battaglini, Lorenzo Ball, Filippo Sanfilippo, Iole Brunetti, Janus Christian Jakobsen, Gisela Lilja, Hans Friberg, Pedro David Wendel-Garcia, Paul J. Young, Glenn Eastwood, Michelle S. Chew, Johan Unden, Matthew Thomas, Michael Joannidis, Alistair Nichol, Andreas Lundin, Jacob Hollenberg, Naomi Hammond, Manoj Saxena, Annborn Martin, Miroslav Solar, Fabio Silvio Taccone, Josef Dankiewicz, Niklas Nielsen, Anders Morten Grejs, Florian Ebner, Paolo Pelosi, TTM2 Trial collaborators

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An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients by Gianluigi Li Bassi, Jacky Y. Suen, Heidi J. Dalton, Nicole White, Sally Shrapnel, Jonathon P. Fanning, Benoit Liquet, Samuel Hinton, Aapeli Vuorinen, Gareth Booth, Jonathan E. Millar, Simon Forsyth, Mauro Panigada, John Laffey, Daniel Brodie, Eddy Fan, Antoni Torres, Davide Chiumello, Amanda Corley, Alyaa Elhazmi, Carol Hodgson, Shingo Ichiba, Carlos Luna, Srinivas Murthy, Alistair Nichol, Pauline Yeung Ng, Mark Ogino, Antonio Pesenti, Huynh Trung Trieu, John F. Fraser, the COVID-19 Critical Care Consortium

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Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, obs... by Luis Felipe Reyes, Srinivas Murthy, Esteban Garcia-Gallo, Laura Merson, Elsa D. Ibáñez-Prada, Jordi Rello, Yuli V. Fuentes, Ignacio Martin-Loeches, Fernando Bozza, Sara Duque, Fabio S. Taccone, Robert A. Fowler, Christiana Kartsonaki, Bronner P. Gonçalves, Barbara Wanjiru Citarella, Diptesh Aryal, Erlina Burhan, Matthew J. Cummings, Christelle Delmas, Rodrigo Diaz, Claudia Figueiredo-Mello, Madiha Hashmi, Prasan Kumar Panda, Miguel Pedrera Jiménez, Diego Fernando Bautista Rincon, David Thomson, Alistair Nichol, John C. Marshall, Piero L. Olliaro, the ISARIC Characterization Group

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Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis by Gianluigi Li Bassi, Kristen Gibbons, Jacky Y. Suen, Heidi J. Dalton, Nicole White, Amanda Corley, Sally Shrapnel, Samuel Hinton, Simon Forsyth, John G. Laffey, Eddy Fan, Jonathon P. Fanning, Mauro Panigada, Robert Bartlett, Daniel Brodie, Aidan Burrell, Davide Chiumello, Alyaa Elhazmi, Mariano Esperatti, Giacomo Grasselli, Carol Hodgson, Shingo Ichiba, Carlos Luna, Eva Marwali, Laura Merson, Srinivas Murthy, Alistair Nichol, Mark Ogino, Paolo Pelosi, Antoni Torres, Pauline Yeung Ng, John F. Fraser, The COVID-19 Critical Care Consortium

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