Interleukin-10 regulates TNF-alpha-converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism. 由 Brennan, F, Green, P, Amjadi, P, Robertshaw, H, Alvarez-Iglesias, M, Takata, M

The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. 由 Sacre, S, Andreakos, E, Kiriakidis, S, Amjadi, P, Lundberg, A, Giddins, G, Feldmann, M, Brennan, F, Foxwell, B

Regulatory T-cell suppression is restored following methotrexate-mediated demethylation of the Foxp3 upstream enhancer in patients with rheumatoid arthritis 由 Cribbs, A, Kennedy, A, Penn, H, Amjadi, P, Green, P, Read, J, Brennan, F, Gregory, B, Williams, R

Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells. 由 Beavis, P, Gregory, B, Green, P, Cribbs, A, Kennedy, A, Amjadi, P, Palfreeman, A, Feldmann, M, Brennan, F

Treg Cell Function in Rheumatoid Arthritis Is Compromised by CTLA-4 Promoter Methylation Resulting in a Failure to Activate the Indoleamine 2,3-Dioxygenase Pathway 由 Cribbs, A, Kennedy, A, Penn, H, Read, J, Amjadi, P, Green, P, Syed, K, Manka, S, Brennan, F, Gregory, B, Williams, R

Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway. 由 Cribbs, A, Kennedy, A, Penn, H, Read, J, Amjadi, P, Green, P, Syed, K, Manka, S, Brennan, F, Gregory, B, Williams, R

Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function. 由 Brennan, F, Smith, N, Owen, S, Li, C, Amjadi, P, Green, P, Andersson, A, Palfreeman, A, Hillyer, P, Foey, A, Beech, J, Feldmann, M

Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis. 由 Andersson, A, Sumariwalla, P, McCann, F, Amjadi, P, Chang, C, McNamee, K, Tornehave, D, Haase, C, Agersø, H, Stennicke, V, Ahern, D, Ursø, B, Trowsdale, J, Feldmann, M, Brennan, F

TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues. 由 Zhang, Z, Gorman, C, Vermi, A, Monaco, C, Foey, A, Owen, S, Amjadi, P, Vallance, A, McClinton, C, Marelli-Berg, F, Isomäki, P, Russell, A, Dazzi, F, Vyse, T, Brennan, F, Cope, A