Beyond the List: Bioagent-Agnostic Signatures Could Enable a More Flexible and Resilient Biodefense Posture Than an Approach Based on Priority Agent Lists Alone by Owen P. Leiser, Errett C. Hobbs, Amy C. Sims, George W. Korch, Karen L. Taylor

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Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. by Aartjan J W te Velthuis, Sjoerd H E van den Worm, Amy C Sims, Ralph S Baric, Eric J Snijder, Martijn J van Hemert

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Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation by Joshua M. Thornbrough, Babal K. Jha, Boyd Yount, Stephen A. Goldstein, Yize Li, Ruth Elliott, Amy C. Sims, Ralph S. Baric, Robert H. Silverman, Susan R. Weiss

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Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung by Fuyi Xu, Jun Gao, Jun Gao, Silke Bergmann, Amy C. Sims, David G. Ashbrook, Ralph S. Baric, Ralph S. Baric, Yan Cui, Colleen B. Jonsson, Kui Li, Robert W. Williams, Klaus Schughart, Klaus Schughart, Klaus Schughart, Lu Lu

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Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis by Vineet D. Menachery, Lisa E. Gralinski, Hugh D. Mitchell, Kenneth H. Dinnon, Sarah R. Leist, Boyd L. Yount, Rachel L. Graham, Eileen T. McAnarney, Kelly G. Stratton, Adam S. Cockrell, Kari Debbink, Amy C. Sims, Katrina M. Waters, Ralph S. Baric

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Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury by Amy C. Sims, Hugh D. Mitchell, Lisa E. Gralinski, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Mariam Lam, M. Leslie Fulcher, Ande West, Richard D. Smith, Scott H. Randell, Thomas O. Metz, Timothy P. Sheahan, Katrina M. Waters, Ralph S. Baric

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Metatranscriptomics analysis reveals a novel transcriptional and translational landscape during Middle East respiratory syndrome coronavirus infection by Ethan J. Fritch, Wes Sanders, Amy C. Sims, Laura E. Herring, Natalie K. Barker, Athena A. Schepmoes, Karl K. Weitz, Jordan R. Texier, Dirk P. Dittmer, Lee M. Graves, Richard D. Smith, Katrina M. Waters, Nathaniel J. Moorman, Ralph S. Baric, Rachel L. Graham

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MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses by Ernesto S. Nakayasu, Carrie D. Nicora, Amy C. Sims, Kristin E. Burnum-Johnson, Young-Mo Kim, Jennifer E. Kyle, Melissa M. Matzke, Anil K. Shukla, Rosalie K. Chu, Athena A. Schepmoes, Jon M. Jacobs, Ralph S. Baric, Bobbie-Jo Webb-Robertson, Richard D. Smith, Thomas O. Metz

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV by Timothy P. Sheahan, Amy C. Sims, Sarah R. Leist, Alexandra Schäfer, John Won, Ariane J. Brown, Stephanie A. Montgomery, Alison Hogg, Darius Babusis, Michael O. Clarke, Jamie E. Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y. Feng, Tomas Cihlar, Robert Jordan, Mark R. Denison, Ralph S. Baric

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Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses by Vineet D. Menachery, Amie J. Eisfeld, Alexandra Schäfer, Laurence Josset, Amy C. Sims, Sean Proll, Shufang Fan, Chengjun Li, Gabriele Neumann, Susan C. Tilton, Jean Chang, Lisa E. Gralinski, Casey Long, Richard Green, Christopher M. Williams, Jeffrey Weiss, Melissa M. Matzke, Bobbie-Jo Webb-Robertson, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Richard D. Smith, Katrina M. Waters, Michael G. Katze, Yoshihiro Kawaoka, Ralph S. Baric

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A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. by Hugh D Mitchell, Amie J Eisfeld, Amy C Sims, Jason E McDermott, Melissa M Matzke, Bobbi-Jo M Webb-Robertson, Susan C Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L Ellis, Jean H Chang, Robert A Heegel, Maria L Luna, Athena A Schepmoes, Anil K Shukla, Thomas O Metz, Gabriele Neumann, Arndt G Benecke, Richard D Smith, Ralph S Baric, Yoshihiro Kawaoka, Michael G Katze, Katrina M Waters

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A compendium of multi-omics data illuminating host responses to lethal human virus infections by Amie J. Eisfeld, Lindsey N. Anderson, Shufang Fan, Kevin B. Walters, Peter J. Halfmann, Danielle Westhoff Smith, Larissa B. Thackray, Qing Tan, Amy C. Sims, Vineet D. Menachery, Alexandra Schäfer, Timothy P. Sheahan, Adam S. Cockrell, Kelly G. Stratton, Bobbie-Jo M. Webb-Robertson, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Young-Mo Kim, Carrie D. Nicora, Zuleyma Peralta, Alhaji U. N’jai, Foday Sahr, Harm van Bakel, Michael S. Diamond, Ralph S. Baric, Thomas O. Metz, Richard D. Smith, Yoshihiro Kawaoka, Katrina M. Waters

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Multi-omics of NET formation and correlations with CNDP1, PSPB, and L-cystine levels in severe and mild COVID-19 infections by Lisa M. Bramer, Robert D. Hontz, Amie J. Eisfeld, Amy C. Sims, Young-Mo Kim, Kelly G. Stratton, Carrie D. Nicora, Marina A. Gritsenko, Athena A. Schepmoes, Osamu Akasaka, Michiko Koga, Takeya Tsutsumi, Morio Nakamura, Ichiro Nakachi, Rie Baba, Hiroki Tateno, Shoji Suzuki, Hideaki Nakajima, Hideaki Kato, Kazunari Ishida, Makoto Ishii, Yoshifumi Uwamino, Keiko Mitamura, Vanessa L. Paurus, Ernesto S. Nakayasu, Isaac K. Attah, Andrew G. Letizia, Katrina M. Waters, Thomas O. Metz, Karen Corson, Yoshihiro Kawaoka, Vincent R. Gerbasi, Hiroshi Yotsuyanagi, Kiyoko Iwatsuki-Horimoto

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